13 Resources on The Role of Histamine and Tourette Syndrome

Histamine is involved in immune responses and inflammation, helps regulate physiological function in the gut, and acts as a neurotransmitter. In recent years it has increasingly been linked to Tourette syndrome.

Research publications on the role of histamine neurotransmission in Tourette syndrome are listed below. Please also see these articles on our website:

Study Links Histamine, Genetics, Diet, and Behavior

Histamine Injections and Sublingual Drops in Allergy Treatment 

Research Articles:

• Increasing histamine neurotransmission in Gilles de la Tourette syndrome  Full article
• L-histidine decarboxylase and Tourette’s syndrome.  Full article
• Histidine decarboxylase deficiency causes Tourette syndrome: parallel findings in humans and mice. Abstract.
• Genetic susceptibility and neurotransmitters in Tourette syndrome.  Abstract
• Nondopaminergic neurotransmission in the pathophysiology of Tourette syndrome.  Abstract
• Support of the histaminergic hypothesis in Tourette syndrome: association of the histamine decarboxylase gene in a large sample of families.  Abstract
• The histaminergic network in the brain: basic organization and role in disease.  Abstract
• Searching for Tourette’s syndrome gene. Part 2. Patient’s genome variability.  Abstract
• Rare copy number variants in Tourette syndrome disrupt genes in histaminergic pathways and overlap with autism.  Abstract
• Increasing histamine neurotransmission in Gilles de la Tourette syndrome. (No abstract available; Pubmed)
• Treating mutation that causes low histamine levels may be behind some tic disorders.  (No abstract available; Pubmed)