Actos/pioglitazone

[faith]

Has anyone here heard of the drug Actos (pioglitazone) being used for autoimune diseases? This is the next thing our DAN doc wants us to try. It is supposed to be a drug used for diabetes, but apparently they have used it experimentally (not FDA approved) for autoimune diseases like MS, etc. I think the premise is that they believe that tics and tourettes is an autoimmune disease in which the bodies tissues attack itself, and the myelin of the nerves are injured and somehow this drug is supposed to aid in the repair of the myelin. But it takes quite a while, like about 9 months. (Carolyn, has your docs ever talked about this?)

 

I'm a little leary of this, because it is a drug. I asked about side effects and he said maybe a little weight gain or swelling around the undereyes. I don't know what to do. He said it wouldn't interfere with any other treatments so I wonder if I could have my son take it, but still persue other avenues.

 

I feel like I may have hit a little dead end or plateau with the Dan doctor. I asked about testing for metals (which we are doing with naturopath anyway) but he acted like he wanted to try other things first, and he only likes to do one thing at a time. I told him that I went ahead with the food sensitivity test with the naturo since we didn't really see anything with the elimination diet he put us on (and I was desperate!) and he said that was okay, but he feels its not a very accurate test. I think I will share with him whatever happens, and I also asked if he had any objections if the naturo did any homeopathic treatments, and he said no, (but I think he probably doesn't think much about that).

 

So I'm wondering if you all had any experiences with DAN docs vs. naturo's. Did you just get inputs from both or is best just to stick with the one? I guess no one doc can do all, and its best to get the best of both worlds, is how I feel. Just wondering how to proceed? Anyone have more success and options with naturo? We will have our consult tomorrow, so I hope she can better lead us.

 

Also, when I showed him my e-mail correspondence with the chiro/nutritionist doc who said that he believed the folinic acid was the wrong form to use for the methylation pathway, he said that "this guy is all wet, he's very wrong". He showed me the diagram of methylation paths and explained, and well now I just feel like the scarecrow from the wizard of oz trying to figure out which way to go!! Oh, well.

 

Any thoughts? Thanks

Faith

[Guest]

Faith,

 

My docs have never talked about Actos or tics being part of an autoimmune disease.

 

I haven't ever used a naturo doctor so I can't comment on them. I work with two doctors, one local (3 1/2 hours from me-that's local to me as we have no DAN docs around here) and one that is a great distance from me. Both of them are DAN doctors. I work with the long distance one for my allergy treatments, but the local one for chelation, yeast, supplements, etc. I find it challenging to work with two doctors for this because you find yourself deciding whether you should listen to doc 1 or doc 2 on this. For example, my allergy doc doesn't seem to be concerned with giving an anitibiotic here and there or a topical antibiotic for my so called acne which even my family doc thought was acne. It's not acne though as I found it was an allergy reaction to coconuts. On the other hand my chelation doc is very anti-med anything(except the antifungal Nystatin, but when I said I didn't want to do that he didn't push it any further). He didn't want me to do a topical antibiotic for my face, antibiotic for ear infections, etc. Even though they have similar goals the way they work is very different, and I tend to leave the allergy stuff to my allergy doctor and anything related to chelation (including supps., yeast, mb12, etc.) to my chelation doctor.

 

As for the folinic vs. folic, why don't you just give your son an experimental try with folic if you think folinic may not be the correct path for him. All kids are different. Maybe your son does respond to folic better, but you won't know unless you try. Check this post out about folinic vs. folic as Dr. Neubrander's brother who works in his clinic knows a lot about the treatments provided to his patients & answers many questions including this one: http://www.autismweb.com/forum/viewtopic.p...highlight=folic

It explains that folinic is the the more active form and the more active form of something can also sometimes mean more side effects, etc. Also do a search on that forum for more related questions and answers.

 

Carolyn

[Cum Passus]

Hi,

 

First forgive me for being stupid, but there is a personal message from kimwal I see at the top of this page right now is this for me? I wasn't sure as I don't know much about computers or the way forums work. If it is I just wanted to say the Natural Calm I baught at The Vitamin Shoppe. It was on sale Sat. for $16. If this was for someone else forget I said anything.

 

Faith,

 

I just wanted to let you know we went 11 months with no drugs, and came to a point when we had to do something, anything to calm our son down. he has been on Risperdal since Oct. and we just took him off the evening dose a couple of week ago to see if he still was calm from the Natural Calm. So far so good. We are going to slowly take him off the morning dose. I feel the meds helped to get him to a calm point so I could try natural stuff, and see how he was doing on them. He was waxing all the time and I was so upset I couldn't tell if anything natural was working. I'm so happy that I feel like I'm getting somewhere. My husband feels we should not seek out Dr. after Dr. because it is overwelming. He really believes we should let the TS run its course, and our son will be fine. Mind you this in his own opinion because he feels what his parents didn't know about TS when he was a child, didn't hurt him. He really wants me to just keep up with the healthy foods and use as little supp. as possable. I just wanted to give you his take on it, I feel a little more like a mother hen. wanting to spare him of all TS symptoms. But some times I look at how well my husband has out grown the TS I have to listen to him a little thinking maybe he is right?

 

C.P.

[Chemar]

CP

the PM would have to be for you as the pop up box only displays for the person it is intended for

Just go into the section at the top right that says New Messages and you can read it

 

 

 

Faith

I personally dont agree with this doct0rs premise about TS being an autoimmune disease

 

I will be back to post more later on this

[Chemar]

Faith

I am still totally puzzled by your doc's rationale and as to why on earth he feels a diabetes med that lowers blood glucose would benefit your growing child

 

http://www.actos.com/sub_sec1_about_actos.asp

[kim]

This might be helpful

 

http://special-needs.adoptionblogs.com/web...-boosting-actos

 

I have read of Actos use on the autism sites. If you goggle actos+inflammation or actos+myelin, you can get more info.

[faith]

Kim, you are a genius at finding info! I searched forever and never came up with that. Yes, this is exactly what I am referring to. (Chemar, please look at that link from Kim's post above). And as the blog mentions Dr. Boris, good old Dr. Boris once again, is our doc!

 

If my son were an autistic patient, I think I would have no problem trying that, but I don't know about our situation. The doc says it has been used for MS, ADHD with about 50-60% success (because I asked) but I don't think he did for anyone with tics/TS (because I asked!). So I think this is trial and error, not sure.

As I said, he didn't seem to want to go forward with anything else yet (why not test for metals -- yea, I asked! -- because I would think that would be a more plausible contributor, no?) I just wanted to see what he would say. I think his way is to do one thing at a time (as he says) and least invasive first. But..I need help now!

 

Anyway, I saw naturopath this morming with results of ALCAT food sensitivity and metals urine challenge.

I think I'll post on separate so as not to confuse the subject. Sorry to keep you in suspense! But I'm sure I'll have a whole other list of questions for that one!

 

Thanks

Faith

[Chemar]

thanks for that link Kim, tho sorry...I still do NOT agree about Tourette Syndrome being autoimmune

 

Correct me if I am wrong but most TS/tics patients need BOOSTING of their immune system..at least that is what the anecdotal evidence seems to indicate...ie when the immune system is built up, they seem to do better

 

In autoimmunity, the immune system is hyperactive and so boosting it would have detrimental effects and so cause an escalation in tics....not what a majority of folks seem to see

 

Dealing with autoimmunity in my son re the Crohn's disease has taught me a lot about autoimmune processes, and I personally just do not see the fit between this and TS..........perhaps with other tic disorders and certainly with PANDAS/PITANDS yes.............but with TS???? TS is known to be a malfunction in the dopaminergic system and centered in the basal ganglia.....and so far I havent seen any research that would suggest that this is related to the myelin sheath being damaged by an autoimmune reaction in genetic Tourette Syndrome

I realise that MUCH research still needs to be done and that I may be proved wrong on this....but for now, I just do not see the connection between autoimmunity and TS

[patty]

Faith,

 

We have seen alot of doctors in the past months, including two NDs, 3 chiropractors, .... In my opinion, when you start to wonder or doubt about what your doctor is doing and w/o much improvement over the course of the treatment, i think it is time to reevaluate if this is the right doctor for your son.

 

I believe the first step toward healing is finding a good doctor. I know this could be difficult depends upon where you live. I was very fortunate to come across some good doctors who referred other doctors who they think can help me. In looking back, my son had a few bad doctors, i was so desperate at that time, i didn't see it.

 

In the beginning, we saw 4/5 doctors at the time, it was stressful for my son as well as for myself. When my son was doing better, i decided to take a short break and then evaulate what to do next. That's when i decided to do one thing at a time. It helps to see what is helping and the dr. appt. are not as overwhelming.

 

Faith, i know you have been thru a lot of doctors and tried different things. Don't give up, for everything you tried that is not working only brings you a step closer to what will work because you have gone thru the elimination process.

 

Patty

[kim]

Faith,

 

I want to say, right off here, I am not trying to make any case for or against the use of Actos for your son.

This is what I suspect, and realize, I have ZERO medical background, I just read a lot . After you read this, I will perfectly understand, if you want to add me to your "ignore poster list." but let's try it anyway!

 

I wonder if any Pandas Moms or anyone else can comment on whether they think this study is specifically looking at a PANDAS subset? The sentence about common infections, are they talking specifically Strep?

 

http://www.ncbi.nlm.nih.gov/entrez/query.f...p;dopt=Abstract

 

Increased serum levels of interleukin-12 and tumor necrosis factor-alpha in Tourette's syndrome.Leckman JF, Katsovich L, Kawikova I, Lin H, Zhang H, Kronig H, Morshed S, Parveen S, Grantz H, Lombroso PJ, King RA.

Child Study Center, Yale University School of Medicine, New Haven, CT 06520-7900, USA. james.leckman@yale.edu

 

Now this part gets confusing in my mind. It looks to me, like Acto's is suspected to be helpful where autoimmune disease or inflammation (how closely are autoimmune and inflammation related?) are thought to be a problem. The cellular and humoral immune system, and the possibility of an overactive TH2 response (humoral..known to cause inflammation ie allergies, asthma etc.)may be something your Dr. is looking at. I'm sure, he has a lot of test results, and he may be basing the use of Actos on some marker, that indicates inflammation? Maybe he was hoping that the supplement plan that he has your son on, would straighten things out. Now he may be looking at trying to control symptoms, by reducing suspected inflammation? That is the question, I would ask him. There are many natural substances that can do that too.

 

Here is a published study on the use of Actos, by your Dr. B. Small study, looks pretty PANDAs specific to me?

 

http://www.pubmedcentral.nih.gov/articlere...tid=1781426#B42

Effect of pioglitazone treatment on behavioral symptoms in autistic children..Boris

 

Since your son tested positive to the MTHFR mutation, I'm sure that is playing into what he feels may be helpful also.

 

The bottom line is, do you trust this Dr? These decisions, are so hard. We are not scientists, and these things are so complex.

 

If I haven't confused you enough already, read this. Maybe you can comment, on what you see in your son, if anything, that relates to any of this. This is probaably not a great source of info, but it is quite simply written.

 

 

Pathogen defense mechanisms. When an immature immune cell is exposed to a virus, cancer, yeast, or intracellular bacteria (for example mycoplasma or chlamydia pneumonia), a Th1 response should be initiated. Viruses, especially herpes viruses such as EBV, CMV or HHV6, make proteins that mimic a particular cytokine. By this means the virus deceives the immune system into thinking that the threat is not coming from a virus. The immune system counters with too little of a Th1 response, the virus remains concealed and the infection becomes active or chronic. It is now thought that many, if not most, pathogens have this defensive ability.

Immune system imbalance. In the above example, the virus has increased its chances of survival by diverting an immune system which is out of balance. It would have been able to respond more accurately if it were healthier. Immune system health is influenced by how we eat and think, our exposure to chemicals and our genetic heritage.

 

There are many natural agents available to help restore balance in an underactive Th1 arm. These include:

Omega-3 fatty acids, monounsaturated fats found in olive and hazelnut oils, vitamin A cod liver oil, l-Glutamine, Silica, digestive enzymes, friendly intestinal flora or soil based organisms (SBOs), ginseng (Red Korean or concentrated Siberian Ginseng extract), chlorella (spirulina and some other sea vegetables may have similar benefits), thyroid hormones, garlic (raw or aged extract), l-Glutathione (or products that raise levels), DHEA or AED (androstendiol), UV-A light, vitamin E, transfer factor (antigen specific) - protein immunomodulators extracted from colostrum, colostrum, low dose naltrexone, IP6, lentinian and certain other mushrooms, Thymus extracts, licorice root, dong quai, beta 1,3-glucan, noni, neem, gingko biloba, exercise, water (to aid detoxification), a positive attitude and prayer, the ability to forgive and be compassionate, and having long-term goals.

 

Factors that induce Th2 cytokines and suppress cell-mediated immunity. Processed, heated vegetable oils high in trans-fatty acids and linoleic acid (safflower, soy, canola, corn and sunflower), glucose (white sugar), asbestos, lead, mercury and other heavy metals, pesticides, air and water pollutants, progesterone, prednisone, morphine, tobacco, cortisol (in high doses), HIV, candida albicans, HCV, E coli and many other pathogens, continuous stress, thalidomide, UV-B light, pregnancy, melatonin (conflicting research suggests that high levels induce Th2 cytokines while very small amounts induce Th1 cytokines), alcohol (animals studies show that ethanol definitely suppresses Th1 cytokines and induces Th2; beer was not tested and there are some indications it may help), streptococcus thermophilis (sometimes found in yoghurt), candidiasis, circulating immune complexes (CICs - caused by a combination of leaky gut syndrome and poor digestion of proteins due to a lack or HCl and digestive enzymes), sedentary lifestyle, negative attitudes, low body temperature, acid saliva pH, chronic insomnia, inability to dream, weight lifting, and steroids (for muscle gain).

 

I just want to stress, that I don't understand all of this, by a long shot. I'm only trying to give you some info. to look at, that may give you some idea's on questions for your Dr.

[faith]

Are you kidding, Kim, you are a gem. Your voice and others like you are desperately needed. Again I say, how do you come up with this stuff?! When I told Dr. Boris that I wanted to find out more about this before we tried it he just wrote on a peice of paper "Actos/and PPARs. and said I could find some stuff on the computer but there's probably very little. Why didn't he direct me to these things you are finding? I'm sure he must know that was published somewhere. Sheesh!

 

I agree, it is very difficult to decipher with only an MBA in motherhood, but that's not gonna stop us from trying. So yes, I'm liking that stuff about the imflammatory process being a factor. Now I just gotta figure out what Interleukin-12 and TH2 and TH1 are! But yes, I think I'm further understanding the rationale of all this, however, my one concern is that most of this is all really involving the autism community and the symptoms that go with that. I'm not really sure how this fits in with the tics. That's my problem with it.

Yes, I think my doctor tried the other stuff first, and feels since it didn't show any response yet, maybe this is the next thing. I don't just want my son to be an experiment to add to the statistics.

 

This info helps a little, because what I'm feeling is that we havn't exhausted the other possibilities (treatments) yet, (and I will post about this separately), but I think I'm going to talk about this with the naturopath. She has opened up some new avenues based on the test results my son had. I like this doctor, because I think the naturo's way is to really study an individual's case and treat it individually, and I can see that so far she has done that.

 

Regarding the inflammatory response, I'm thinking that no it's not totally PANDAS related, they don't mention that word in that Pubmed excerpt. I find it very interesting. I know there is something there. When we talk of "exacerbations" of symptoms (OCD, tics, etc.) somehow I think its all a matter of how you look at it. Maybe its the root of all of it, just when inflammation is at its worst, i.e. with an infection, strep, viral, or other unknown illness the body harbours, that's when the extreme onset occurs, but with the typical wax and wane tics, maybe its the same thing, just not as severe an infection. I say this because, even though I have seen tics here and there with my son since 3 1/2 yrs. old, last year (as I mentioned in another post) one weekend he started blinking and rolling eyes rapidly and had a real bout of hyperactivity at a birthday party. When we left the party he said his throat hurt, and after we saw doctor he said it was strep and gave antibiotic (amoxycilin). I'm telling you that with 24 to 48 hours later the blinking was over. A few weeks later we went to an infectious disease doctor who tested for the PANDAS connection, but his titres were within normal range. So even though he didn't show the strep titires, I'm sort of almost convinced something was there. That was just too coincidental to me. But I have nothing to go on.

 

I'm just typing away of what comes to my mind, I don't claim to know anything either. But we should all just keep brainstorming. Like Melanie Griffith said in the movie "working girl" when she shows how she came up with her idea from reading something from "Page 6" in the Daily News, and her witchy boss rolls her eyes cause she thought it was a dumb thing to read, she says "You never know where the good ideas are going to come from". Assuming you all saw that movie! I always liked that line.

 

Well, thanks a heap for that and I'm going to read up some more on this.

 

Faith

[kim]

Faith/Chemar,

 

I only have a minute, but I wanted to let you know, that I totally missed something in that Pubmed study.

 

I think this statement, would pertain mostly to the research that has been done, regarding PANDAS

 

BACKGROUND: The hypothesis that common infections can modulate the onset and course of tic disorders and early-onset obsessive-compulsive disorder (OCD) in pediatric populations is longstanding. To date, most investigations have focused on the hypothesis of molecular mimicry and humoral immune responses.

 

But they were looking at something else here

 

This study was carried out to investigate whether cytokines associated with the innate immune response or T cell activation were altered under baseline conditions and during periods of symptom exacerbation.

 

They were looking at a different arm of the immune system, than what is suspected to be problematic in the PANDAS subset, and it appears they found elevation, not only at baseline, but with exacerbations too.

 

Chemar...I find it really interesting that interluken 12 and TNF might be elevated in Crohns and TS. The innate immunity, that the above study was looking at, is the type of immune response, that responds to pathogens, but forms no "memory," that would be the humoral arm of the immune system (memory). The innate is the first line in a healthy functioning immune system. So, if there is a chronic elevation of innate (cellular), it seems it could mean a few things.

 

then there was this

 

Activated T lymphocytes and macrophages play a putative role in the the pathogenesis of Guillain-Barre syndrome. Both cell types secrete tumor necrosis factor-alpha, a cytokine that has well-recognized toxic effects on myelin, Schwann cells, and endothelial cells.

Is the alpha part important? I dont know if the studies mentioned TNF ot TNF alpha?

 

This is the first thing that I have read, that discusses the immune system in regards to anything other than PANDAS, I believe.

 

This was kind of interesting too....It does say "tic disorders" not TS

 

J Child Adolesc Psychopharmacol. 2005 Apr;15(2):285-92. Links

Association of common cold with exacerbations in pediatric but not adult patients with tic disorder: a prospective longitudinal study.Hoekstra PJ, Manson WL, Steenhuis MP, Kallenberg CG, Minderaa RB.

Child and Adolescent Psychiatry Center, Groningen, The Netherlands. Pieter.Hoekstra@kjpnn.nl

 

Cross-sectional data and case studies suggest a temporal relationship between fluctuations in tic severity and preceding infections. In this study, we aimed to examine this possible relationship in a prospective longitudinal design. Two groups of tic disorder patients were included, a pediatric group between 7 and 15 years of age (n = 20), and an adult group over 15 years of age (n = 41). During a 24-week period, participants were asked to fill out weekly self questionnaires regarding the presence of tic exacerbations and the experience of the common cold. In addition, 6 throat swabs were taken at monthly intervals and cultured for streptococci; also, 3 serial serum assessments of streptococcal antibodies were performed at 8-week intervals. In the pediatric group, our results indicated a strong association between the self report of a common cold and a symptom exacerbation 4 weeks later (Odds ratio = 4.685; p = 0.001). In the adult group, we found no association between reports of common cold and tic exacerbations. Association with streptococcal infections could not be determined owing to the limited number of observed streptococcal infections. Thus, this study points to a hitherto unknown association of common viral infections with tic exacerbations in children, which may support the involvement of immune dysregulation in tic disorders.

 

 

I have to sign off, but I wanted to post some of this, so others could point out where I'm wrong? or their thoughts on the matter.

[kim]

Faith,

 

I have been meaning to address this for a while, and just haven't had a chance.

 

Again I say, how do you come up with this stuff?!

I promise you, no credit should go to me for that. Every single thing, that I have learned about this disorder is almost always directly related to another person/parents sharing.

I had no idea how to search effectively, cut or paste links, nothing, when I joined this group and a couple others.

 

The information that is shared on Autism groups has be sooo helpful too. I can't believe they find the time to post all that they do, while dealing with children that are so ill.

 

The other thing that popped into my mind when you were asking that question was, "I'm being led by faith," kind of ironic hau?

 

I got directly to the info. that was tied to your doc, quickly, both times. It had nothing to do with any skill on my part!

 

I'm going to include a couple of other things that I have ran across, since you brought up this topic.

 

Cell types in allergic disease

 

http://medic.uth.tmc.edu/hcprof/00000770.htm

 

Inflammation has three major components: recruitment , where the inflammatory cells are drawn from the circulation under direct a chemical influence called chemotaxis; altered traffic, where the inflammatory cells are held at the site of developing inflammation; and activation, where the inflammatory cells exert their influence , e.g. producing cytokines, lytic enzymes, phagocytosis, etc. In allergic inflammation, a combination of TH2 cell and mast cell activity appear to be most responsible for the initiation of the eosinophilic activities.

 

A major source of chemotactic molecules is the activated mast cell. TNFa is a major proinflammatory cytokine whose activities include chemotaxis. Activated mast cell secrete TNFa and therefore may directly influence recruitment of eosinophils. Once activated, eosinophils are themselves a source of secreted TNFa which may serve to continue the recruitment of new eosinophils to the site of inflammation.

 

Here's TNFa again. Many of our kids seem to have allergy problems.

 

Allergy testing/control sure was a vital step in improving things for my oldest son.

 

For anyone who might not have read the study that I posted from Pub Med above, this is the statement I'm referring to;

 

RESULTS: Interleukin-12 and tumor necrosis factor alpha concentrations at baseline were elevated in patients compared with control subjects. Both of these markers were further increased during periods of symptom exacerbation.

 

Then (again from above)

 

Activated T lymphocytes and macrophages play a putative role in the the pathogenesis of Guillain-Barre syndrome. Both cell types secrete tumor necrosis factor-alpha, a cytokine that has well-recognized toxic effects on myelin, Schwann cells, and endothelial cells.

 

And

 

http://72.14.205.104/search?q=cache:vYQ-NG...t=clnk&cd=4

 

The scientists, to their surprise, discovered that the teenage brain undergoes an intense overproduction of gray matter (the brain tissue that does the “thinking”). Then a period of “pruning” takes over, during which the brain discards gray matter at a rapid rate. 2This process is similar to pruning a tree: cutting backbranches stimulates health and growth. In the brain, pruning is accompanied by myelination, a process in which white matter develops. White matter is fatty tissue that serves as insulation for the brain’s circuitry, making the brain’s operation more precise and efficient.

 

Could this process be responsible (at least in some cases) for the improvement we see often, in the teen years?

[faith]

Thanks Kim for all that. I'm loving all this info even tho I must admit the fancy scientific words get me a little confused when I've never heard of that word before. Like the TNF, I think there's something there and want to read more on it to put it all together. I'm just thinking off the top of my head here, so I might sound all over the place. But I keep going over the stuff, and trying to link it together with tics/ts. Do you ever notice tourettes or tic disorders are rarely mentioned in most of research--clearly all the stuff we know about inflamation, demyelination, allergies, etc. could certainly apply to tics and such-- but every other disease is mentioned, it's like its almost never acknowledged or something. Why is so little research done in relation to it?

 

And the part about the "pruning" in teen years (see above post for anyone interested) is interesting. I'm thinking that could happen at any time, not just teen years, although it is probably more typical. I can't help remember one time when in the pediatricians office when I first wanted to talk to the doctor about my son having tics, the med assistant told me that her daughter (who was now 12) had three tics going on when she was in first grade (including a little vocal), and it lasted about six months, and that was it. Her take was that the nervous system was "maturing". We couldn't talk too long, but she saw I was upset, so told me of this. It gave me some hope and food for thought. Why did that girl have a few tics and than totally gone without any intervention? Something in the body has to be awry. Same thing with MS. Why do some go so long with remissions, and some totally deteriorate at a younger age? So it's interesting, but again I say why so little reference to TS? It can't be that it's so uncommon that it doesn't warrant any study. Frustrating.

 

So here we are, left to ponder. I bet if we all put our heads together in the same room for several months ....

 

Sorry if this is all over the place, just wanted to get my thoughts off my chest, but I'm still in my pj's so I'm not too articulate this morning!

 

Regards

Faith

[Guest]

Faith,

 

Maybe it's because most doctors & researchers are closed minded and think like a friend of mine regarding tics/tourette's. I've been struggling diet wise again this whole week, only wanting McDonalds day and night. A good friend of mine(who has ts and also has a sibling with ts) and I were discussing what we were going to have for breakfast. I had mentioned that I didn't know because my waffles weren't turning out without eggs(by the way I decided leaving eggs is better than being frustrated and going and getting McDonalds). I was then asked who told me that proper diet helps tics. I replied that my doctors, others at this forum, some family members, and most importantly I notice a difference. I notice a huge difference. I was then told that Tourette's is neurological and there's no cure for it so diet doesn't have anything to do with it. At that point I could see it was going to turn into a debate that wasn't worth it so I just said that maybe we could change the topic because we both believe differently. In a way knowing that my friend doesn't understand discouraged me. I'm thankful to have Sheila and all of you guys to encourage me when people doubt what treatments you do. So many people in my state are so closed minded. I don't know what I'd do without you guys here. I don't think I could do the treatments that I'm doing now though without this forum and all of you. My neighbors all around me would make me too discouraged.

 

Anyways maybe that's why tics/tourette's hardly exists in any research regarding inflamation, allergies, etc--Tourette's/tics are neurological and there's no cure for it so the other things like inflamation, etc. don't mater. Anyways just an idea because I know a lot of people that think that way. I'm really glad to have this group that doesn't think that way.

 

Carolyn