kkver Posted February 20, 2008 Author Report Share Posted February 20, 2008 I was reading through some older posts and came across this thread. I wanted to add that my son also has a small tumor/cyst on his wrist (a ganglion cyst I believe it is called) that just appeared (I noticed it approx 4-5 months after he exploded with tics nearly over night last spring.) tlkinser Have you got this cyst tested ? I have read some articles where strep infection resides in body causing complication similar to Rheumatic fever. It is kind rare but will give you more clear path to rule out things. http://www.nlm.nih.gov/medlineplus/ency/article/003940.htm Link to comment Share on other sites More sharing options...
Sunshine Posted February 22, 2008 Report Share Posted February 22, 2008 My son's lump was sent off to Pathology for dissection and testing. All that we were told was that it was a 'benign tumor mass'. I would doubt that it was checked for strep, as we had no known issues with strep at that point. I highlight known, as I am now aware that strep, as well as other bacteria and viruses, can hide OH SO WELL! I also highlighted it because I just figured out how to use colour, and it's oh so funky! Sunshine Link to comment Share on other sites More sharing options...
orthomolecular Posted July 16, 2008 Report Share Posted July 16, 2008 I'm not sure why exactly epsom salts is a problem for some. But I am familiar with problems with sulfation. This is the body's way of converting sulfites into sulfates. Only sulfates can be excreted so the WRONG kind of sulfur is known to cause some people a problem. But magnesium sulfate contains the right kind of sulfar; so that is the part that is puzzling me. I think the best sulfur supplement though is SAMe. This can be expensive and after sometime substituted with methionine. I looked up some info on the SNP and it is basically a problem with folic acid (B9). There is a form of B9 recommneded for this type. The problem with sulfur means it has a nutritional basis. I think the genetic testing is one way of confirming high histamine levels. This condition, AKA histadelia, is treated by an orthomolecular approach. And it is true that high doses of B6 would be a problem for this type and even a high protein diet. Another approach and way to possibly research this is metabolic typing (MT). These are fast oxidizers in MT which has macro-nutrient diet recommendations. And MT may also have some supplement info as well, like the correct form of vitamin C to take (ascorbic acid or mineral abscorbates). I mention these approaches because I think they can make the subject a bit easier to wrap your brain around instead of taking it from a DNA methylation prospective. The right form of B9. http://nwclinic.com/L5.html This forum post has a lot of info. http://adhdldsupport.proboards107.com/inde...1126&page=1 This site makes me want to ask if you (the mother) took a prenatal vitamin during pregnancy. Histadelics should avoid B9 especially in high doses. A mother with histadelia would explain why a child would have high histamine levels (or histadelia). (I don't know if it is genetic or congenital; almost the same thing though.) http://www.ehponline.org/members/2006/9166/9166.html But generally problems with methylation can be corrected with the right nutritional approach (working with a qualified professional of course). And methylation problems are important to treat because faulty metthylation will cause faulty DNA methylation. Faulty DNA methylatin is how gene expression is turned on. (This goes back to if it is really genetic or congenital. If the mother had faulty methylation then that might explain why the child has this mutation, perhaps). Another site I like is enzymestuff.com. She explains about using epsom salts in hand lotion, or sprayed on the body, and also explains about sulfation and transulfation. And mentions some enzymes that may help with phenol problems. This type can have reactions to phenols. Link to comment Share on other sites More sharing options...
kim Posted July 17, 2008 Report Share Posted July 17, 2008 I'm not sure why exactly epsom salts is a problem for some. But I am familiar with problems with sulfation. This is the body's way of converting sulfites into sulfates. Only sulfates can be excreted so the WRONG kind of sulfur is known to cause some people a problem. But magnesium sulfate contains the right kind of sulfar; so that is the part that is puzzling me. Ortho, In addtion to the links you supplied, these pages have some good info on why addtional sulfur can be a problem for some and very beneficial for others http://72.14.205.104/search?q=cache:0gVAX8...;cd=1&gl=us CBS (Cystathione-Beta-Synthase) – helps to convert homocysteine into glutathione (major antioxidant in the body). If a defect exists it will affect ammonia detoxification because excess sulfur in the body (endogenous or exogenous sources, ie. supplements like MSM, Epsom Salt or medications such as DMPS) can be converted to ammonia. Also, this defect can affect an enzyme called G6PDH which has negative effects on blood sugar metabolism and red blood cell formation and blood vessel stability (easy bruising, bleeding, broken blood vessels).• CBS C699T (-/-) = no mutation. Lower potential for ammonia detoxification issues. • CBS C699T (+/-) = heterozygous defect. Partial defect. Higher risk for ammonia detoxification issues. • CBS C699T (+/+) = homozygous defect. Both genes affected. Significant propensity for ammonia detoxification issue. Will need to be careful with sulfur containing supplements, ie. MSM and medications, ie. DMPS. http://www.heartfixer.com/AMRI-Nutrigenomi...Beta%20Synthase CBS initiates the trans-sulfuration pathway, converting homocysteine in to cystathionine and its downstream metabolites. This is the most important Methyl Cycle defect and is present in 90% of the patients who we have tested. The CBS defect is an up regulation. CBS is operating at up to ten times its normal rate. Homocysteine and all of the upstream methyl cycle precursors will be “pulled down the CBS drain” to produce toxic levels of cystathionine metabolites. The C699T and (to a somewhat lesser extent) A360A defects are associated with CBS up regulation. Homozygotes (+/+) will be more severely affected than will be individuals heterozygous (+/-) for a CBS abnormality. We treat CBS ( +) individuals with dietary animal protein and sulfate restriction and supplements designed to neutralize ammonia and speed up clearance of sulfite/sulfate. Laboratory findings consist of an elevated urine sulfate level, a low or low normal blood homocysteine level, an elevated or high normal blood ammonia level, and positive findings of ammonia, sulfite, or sulfite upon Asyra testing. My initial observation is that individuals with high heavy metal burdens upon provocative challenge testing are likely to be CBS positive. CBS (+) individuals will be intolerant to sulfur containing drugs, nutritionals, and foodstuffs (I am +/- for CBS A360A and cannot tolerate DMPS or glucosamine sulfate. A cold beer tastes great but I do not like wine, which is high in sulfite). Link to comment Share on other sites More sharing options...
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