Lyme Elisa + Western Blot Results

[duhzse]

Thank you for taking the time to read my post. Since December 17th, 2016, suddenly I have been experiencing episodes of intense anxiety, depression, depersonalization, disassociation, panic etc. These usually happen in the evening, every other day, and last for awhile (from hours to days). At the same time, there is a lot of brain fog, fatigue, and I just know there's something not right in my head, mentally. And I am very certain that it is caused by something physical (hence, why I did lyme testing). I don't have any physical symptoms such as joint aches, but in the beginning I had a constant back of the skull pressure type of headache.

 

Recently, I took a blood test for Lyme. Here are my results.

 

ELISA: 0.92, which is in the EQUIVOCAL range.

Western Blot, Reactive Bands: 41, 58, 66, 93 (IgG) and 41 (IgM)

 

Right now, my doctor is saying to take doxycycline 100mg twice daily for 30 days. Then after the 30 days, I will do a second western blot.

 

Do you guys have any advice what steps I should do from here? Thanks again.

REFERENCE RANGE: <=0.90
INTERPRETIVE CRITERIA:
<= 0.90 NEGATIVE
0.91-1.09 EQUIVOCAL
>= 1.10 POSITIVE
The use of purified VlsE-1 and PepC10 antigens in
this assay provides improved specificity compared
to assays that utilize whole cell lysates of B.
burgdorferi, the causative agent of Lyme disease,
and slightly better sensitivity compared to the
C6 antibody assay.
As recommended by the Food and Drug
Administration (FDA), all samples with positive
or equivocal results in a Borrelia burgdorferi
antibody EIA (screening) will be tested using a
blot method. Positive or equivocal screening test
results should not be interpreted as truly
positive until verified as such using a
supplemental assay (e.g., B. burgdorferi blot).
The screening test and/or blot for B. burgdorferi
antibodies may be falsely negative in early
stages of Lyme disease, including the period when
erythema migrans is apparent.
Test Performed at:
Focus Diagnostics, Inc.
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042 H J Batterman MD

REFERENCE RANGE: NEGATIVE
As per CDC criteria, a Lyme disease IgG
immunoblot must show reactivity to at least 5 of
10 specific borrelial proteins to be considered
positive; similarly, a positive Lyme disease IgM
immunoblot requires reactivity to 2 of 3 specific
borrelial proteins. Although considered
negative, IgG reactivity to fewer specific
borrelial proteins or IgM reactivity to only 1
protein may indicate recent B. burgdorferi
infection and warrant testing of a later sample.
A positive IgM but negative IgG result obtained
more than a month after onset of symptoms
likely represents a false-positive IgM result
rather than acute Lyme disease. In rare
instances, Lyme disease immunoblot reactivity
may represent antibodies induced by exposure to
other spirochetes.
Test Performed at:
Focus Diagnostics, Inc.
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042 H J Batterman MD

 

 

[bws1565]

My son had band 41 and 93 too. Although this in not considered "full blown Lyme" he was better after treatment. If you are having the symptoms you explain, I think you need treatment. I don't know the value of retesting though.