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Thank you for taking the time to read my post. Since December 17th, 2016, suddenly I have been experiencing episodes of intense anxiety, depression, depersonalization, disassociation, panic etc. These usually happen in the evening, every other day, and last for awhile (from hours to days). At the same time, there is a lot of brain fog, fatigue, and I just know there's something not right in my head, mentally. And I am very certain that it is caused by something physical (hence, why I did lyme testing). I don't have any physical symptoms such as joint aches, but in the beginning I had a constant back of the skull pressure type of headache. Recently, I took a blood test for Lyme. Here are my results. ELISA: 0.92, which is in the EQUIVOCAL range. Western Blot, Reactive Bands: 41, 58, 66, 93 (IgG) and 41 (IgM) Right now, my doctor is saying to take doxycycline 100mg twice daily for 30 days. Then after the 30 days, I will do a second western blot. Do you guys have any advice what steps I should do from here? Thanks again. REFERENCE RANGE: <=0.90 INTERPRETIVE CRITERIA: <= 0.90 NEGATIVE 0.91-1.09 EQUIVOCAL >= 1.10 POSITIVE The use of purified VlsE-1 and PepC10 antigens in this assay provides improved specificity compared to assays that utilize whole cell lysates of B. burgdorferi, the causative agent of Lyme disease, and slightly better sensitivity compared to the C6 antibody assay. As recommended by the Food and Drug Administration (FDA), all samples with positive or equivocal results in a Borrelia burgdorferi antibody EIA (screening) will be tested using a blot method. Positive or equivocal screening test results should not be interpreted as truly positive until verified as such using a supplemental assay (e.g., B. burgdorferi blot). The screening test and/or blot for B. burgdorferi antibodies may be falsely negative in early stages of Lyme disease, including the period when erythema migrans is apparent. Test Performed at: Focus Diagnostics, Inc. 33608 Ortega Highway San Juan Capistrano, CA 92675-2042 H J Batterman MD REFERENCE RANGE: NEGATIVE As per CDC criteria, a Lyme disease IgG immunoblot must show reactivity to at least 5 of 10 specific borrelial proteins to be considered positive; similarly, a positive Lyme disease IgM immunoblot requires reactivity to 2 of 3 specific borrelial proteins. Although considered negative, IgG reactivity to fewer specific borrelial proteins or IgM reactivity to only 1 protein may indicate recent B. burgdorferi infection and warrant testing of a later sample. A positive IgM but negative IgG result obtained more than a month after onset of symptoms likely represents a false-positive IgM result rather than acute Lyme disease. In rare instances, Lyme disease immunoblot reactivity may represent antibodies induced by exposure to other spirochetes. Test Performed at: Focus Diagnostics, Inc. 33608 Ortega Highway San Juan Capistrano, CA 92675-2042 H J Batterman MD