Sick Monkies/VaccinesAutism Article

[Mustang Carole]

HI...WOW

 

SICK MONKEYS: RESEARCH LINKS VACCINE LOAD, AUTISM SIGNS

 

BY DAN OLMSTED

 

http://www.ageofautism.com/

 

The first research project to examine effects of the total vaccine

load received by children in the 1990s has found autism-like signs

and symptoms in infant monkeys vaccinated the same way. The study's

principal investigator, Laura Hewitson from the University of

Pittsburgh, reports developmental delays, behavior problems and brain

changes in macaque monkeys that mimic "certain neurological

abnormalities of autism."

 

The findings are being reported Friday and Saturday at a major

international autism conference in London.

 

Although couched in scientific language, Hewitson's findings are

explosive. They suggest, for the first time, that our closest animal

cousins develop characteristics of autism when subjected to the same

immunizations – such as the MMR shot -- and vaccine

formulations – such as the mercury preservative thimerosal --

that American children received when autism diagnoses exploded in the

1990s.

 

The first publicly reported results of this research project come in

both oral and poster presentations on Friday and Saturday at the

International Meeting For Autism Research in London. Poster

presentations must go through a form of peer review before they are

presented at the conference; the papers have not yet appeared in a

scientific journal.

 

In addition to Hewitson's oral presentation today, on Saturday in one

of two related poster presentations, the researchers also are

reporting in their abstract that "vaccinated animals exhibited

progressively severe chronic active inflammation [in gastrointestinal

tissue] whereas unexposed animals did not. We have found many

significant differences in the GI tissue gene expression profiles

between vaccinated and unvaccinated animals." Numerous scientific

studies, as well as many parents, report severe GI ailments in

children with regressive autism.

 

The results are sure to be controversial, in part because they lend

credence to studies first published in 1998 by British pediatric

gastroenterologist Andrew Wakefield, one of Hewitson's co-authors on

these findings. He described an unusual inflammatory bowel condition

in children who had regressed into autism after they received the

measles-mumps-rubella (MMR) vaccination. Wakefield is currently

fighting charges of medical misconduct in Britain over allegations of

conflict-of-interest and improper procedures related to that paper. He

denies the charges.

 

In the program for the conference, the 7th Annual International

Meeting for Autism Research (IMFAR), there are three separate

presentations listed that report results from the overall research

program. The first, an oral presentation entitled "Pediatric Vaccines

Influence Primate Behavior, and Amygdala Growth and Opioid Ligand

Binding" (the "amygdala abstract") was led by Dr. Hewitson and lists

12 co-authors, including five of her colleagues from the University

of Pittsburgh and Dr. Wakefield. Other authors are chemists,

pathologists and psychologists from the universities of Kentucky,

California-Irvine, and Washington.

 

Hewitson's introductory presentation will be followed by two poster

presentations on Saturday; one of the two, "Pediatric Vaccines

Influence Primate Behavior, and Brain Stem Volume and Opioid Ligand

Binding", was led by Wakefield and includes six additional

co-authors.

 

It focuses on the developmental effect of vaccine exposures on brain

growth during infancy. The second, "Microarray Analysis of GI Tissue

in a Macaque Model of the Effects of Infant Vaccination," was led by

Steven Walker of Wake Forest University and performed gene array

analysis on the intestinal tissues of the vaccinated and unvaccinated

monkeys.

 

The studies address – albeit in animals, not children -- one of

the major criticisms by parents and scientists concerned about a

possible link between the greatly stepped-up immunization schedule in

the 1990s, including higher exposure to the mercury preservative, and

autism. While the Food and Drug Administration approves individual

vaccines as safe and effective, and an advisory committee to the

Centers for Disease Control and Prevention recommends the childhood

immunization schedule adopted by the states, the overall health

outcomes from the total vaccine load, versus no vaccinations at all,

have never been compared, the authors said.

 

A bill requiring the government to conduct a study of autism rates in

unvaccinated American children is pending in the U.S. House of

Representatives, co-sponsored by Reps. Carolyn Maloney (D-N.Y.) and

Tom Osborne (R.-Neb.). Just this week, former National Institutes of

Health Director Bernadine Healy called for more research into a

possible vaccine link to autism and said the question had not been

settled, despite repeated assertions to that effect by the CDC, the

Institute of Medicine and the American Academy of Pediatrics.

 

In the abstract for today's oral presentation, the authors noted that

macaques, the type of monkey used in the study, "are commonly used in

pre-clinical vaccine safety testing, but the combined childhood

vaccine regimen, rather than individual vaccines, has not been

studied. Childhood vaccines are a possible causal factor in autism,

and abnormal behaviors and anomalous amygdala growth are potentially

inter-related features of this condition."

 

The study found evidence of both behavioral and biological changes

after the 13 macaque monkey infants were administered proportional

doses, adjusted for age, of the vaccines recommended between 1994 and

1999. Three monkeys were not given any vaccines.

 

"Primate development, cognition and social behavior were assessed for

both vaccinated and unvaccinated infants using standardized tests

developed at the Washington National Primate Research Center." MRI

and PET scans looked for brain changes after administration of the

MMR.

 

"Compared with unexposed animals, significant neurodevelopmental

deficits were evident for exposed animals in survival reflexes, tests

of color discrimination and reversal, and learning sets," the authors

reported. "Differences in behaviors were observed between exposed and

unexposed animals and within the exposed group before and after MMR

vaccination. Compared with unexposed animals, exposed animals showed

attenuation of amygdala growth and differences in the amygdala

binding of [11C]diprenorphine. Interaction models identified

significant associations between specific aberrant social and

non-social behaviors, isotope binding, and vaccine exposure."

 

One of the Saturday abstracts makes the further point that the

research "revealed significant differences between exposed and

unexposed animals" in the kinds of developmental behaviors a mother

might be able to observe, "with delayed acquisition of root, suck,

clasp hand, and clasp foot reflexes." They conclude by noting that

"This animal model examines the neurological consequences of the

childhood vaccine regimen, Functional and … brainstem

anomalies were evident in vaccinated animals that may be relevant to

some aspects of autism. The findings raise important safety issues

while providing a potential animal model for examining aspects of

causation and disease pathogenesis in acquired neurodevelopmental

disorders."

[Chemar]

wow indeed!!!!!

 

thanks for posting it Carole

 

now how many years and millions of kids will it take for them to take note!!!!!!!!!

[peglem]

Thanks for sharing this! I would sure like to see them investigate (in these same test subjects) changes in other body systems as well. The immune system, for instance. I think there is a problem, though, with comparing vaccinated vs. nonvaccinated children in the USA though. I think there are too many life-style variables between the vaccinated and unvaccinated populations. You might get some interesting correlations, but w/o controlling for all the other variables, it won't prove causation.

[kim]

A few things to share here. I'm finding it harder and harder to pray for this man's soul (Offit.... vaccine safety mouth piece and patent holder) and everyone who continues to shove what I consider to be misleading facts down the throats of unsuspecting young parents about the "safety studies" and such. This cat is out of the bag. Gerber is either woefully uninformed or is being outright misleading, IMO as there are numerous studies that DO support the theory that toxins from the environment play a role.

I do not have an autistic child, but I do believe I have children that were harmed by vaccines.

 

Edit...to remove some harsh language

 

Don't miss the dental amalgam article near the bottom

 

http://ca.news.yahoo.com/s/capress/080511/...tism_court_case

 

 

"I think that what's so endearing to me about the anti-vaccine people

is they're perfectly willing to go from one hypothesis to the next

without a backward glance," said Dr. Paul Offit, director of the

Vaccine Education Center at the Children's Hospital of Philadelphia.

and

 

Toxins from the environment could play a role, but currently, data

does not support that they do, Gerber said.

 

 

 

http://www.ageofautism.com/2008/03/paul-offit-the.html

 

The bio below his Op-Ed piece reads: "Paul A. Offit, chief of the infectious diseases division of the Children’s Hospital of Philadelphia, is the author of “Vaccinated: One Man’s Quest to Defeat the World’s Deadliest Diseases.”

 

We thought you should understand the implications of the rest of Dr. Offit's bio (including his disclaimer line in the piece.) Just to be clear. If he's going to speak out in a national publication about the safety of vaccines, you should know that he has a financial interest in vaccinations. And that he has served on the CDC Advisory Committee on Immunization Practices (ACIP.) Perhaps The Times just didn't have enough column inches to spare for that part?

 

Paul Offit makes money every time your child has her 2 month, 4 month and 6 month well visit and receives the Rotateq vaccine, which is now safely ensconced on the AAP vaccine schedule.

 

 

 

 

 

*Aluminum and Vaccine Ingredients: What Do We Know? What Don't We Know?*

by Lawrence B. Palevsky, MD, FAAP

http://www.northportwellnessexpo.com/article-nvic.html

 

- - - -

 

*Is Aluminum the New Thimerosal?*

By Robert W. Sears Issue 146, January/February 2008

http://www.mothering.com/articles/growing_...thimerosal.html

 

 

http://content.karger.com/ProdukteDB/produkte.asp?Doi=107546

 

*Aluminum-induced mitochondrial dysfunction leads to lipid accumulation

in human hepatocytes: a link to obesity*

Mailloux R, Lemire J, Appanna V.

Cell Physiol Biochem. 2007;20(5):627- 38.

 

Mitochondrial dysfunction is the cause of a variety of pathologies

associated with high energy-requiring tissues like the brain and

muscles. Here we show that aluminum (Al) perturbs oxidative-ATP

production in human hepatocytes (HepG2 cells). This Al-induced

mitochondrial dysfunction promotes enhanced lipogenesis and the

accumulation of the very low density lipoprotein (VLDL). Al-stressed

HepG2 cells secreted more cholesterol, lipids and proteins than control

cells. The level of apolipoprotein B-100 (ApoB-100) was markedly

increased in the culture medium of the cells exposed to Al. (13)C-NMR

and HPLC studies revealed a metabolic profile favouring lipid production

and lowered ATP synthesis in Al-treated cells. Electrophoretic and

immunoblot analyses pointed to increased activities and expression of

lipogenic enzymes such as glycerol 3-phosphate dehydrogenase (G3PDH),

acetyl CoA carboxylase (ACC) and ATP-citrate lyase (CL) in the

hepatocytes exposed to Al, and a sharp diminution of enzymes mediating

oxidative phosphorylation. D-Fructose elicited the maximal secretion of

VLDL in the Al-challenged cells. These results suggest that the

Al-evoked metabolic shift favours the accumulation of lipids at the

expense of oxidative energy production in hepatocytes. Copyright ©

2007 S. Karger AG, Basel.

 

PMID: 17762189

 

 

 

*Microarray Analysis of GI Tissue in a Macaque Model of the Effects of

Infant Vaccination* Saturday, May 17, 2008 IMFAR

/

S. J. Walker , Institute for Regenerative Medicine, Wake Forest

University Health Sciences, E. K. Lobenhofer , Cogenics, a Division of

Clinical Data E. Klein , Division of Laboratory Animal Resources,

University of Pittsburgh, A. Wakefield , Thoughtful House Center for

Children, Austin, TX L. Hewitson , Obstetrics, Gynecology and

Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA/

 

Background: There has been considerable debate regarding the question

of an interaction between childhood vaccinations and adverse sequelae in

the gastrointestinal tract, immune system, and central nervous system of

some recipients. These systems, either singly or in combination, appear

to be adversely affected in many ASD children. Although pre-clinical

tests of individual vaccines routinely find the risk/benefit ratio to be

low, previously there has not been a study to examine the effects of the

comprehensive vaccination regime currently in use for infants.

 

Objectives: This study was designed to evaluate potential alterations

in normal growth and development resulting from the vaccine regimen that

was in use from 1994-1999. Specifically, this portion of the study was

to compare the gene expression profiles obtained from gastrointestinal

tissue from vaccinated and unvaccinated infants.

 

Methods: Infant male macaques were vaccinated (or given saline placebo)

using the human vaccination schedule. Dosages and times of

administration were adjusted for differences between macaques and

humans. Biopsy tissue was collected from the animals at three time

points: (1) 10 weeks [pre-MMR1], (2) 14 weeks [post-MMR1] and, (3) 12-15

months [at necropsy]. Whole genome microarray analysis was performed on

RNA extracted from the GI tissue from 7 vaccinated and 2 unvaccinated

animals at each of these 3 time points (27 samples total).

 

Results: Histopathological examination revealed that vaccinated animals

exhibited progressively severe chronic active inflammation, whereas

unexposed animals did not. Gene expression comparisons between the

groups (vaccinated versus unvaccinated) revealed only 120 genes

differentially expressed (fc >1.5; log ratio p<0.001) at 10 weeks,

whereas there were 450 genes differentially expressed at 14 weeks, and

324 differentially expressed genes between the 2 groups at necropsy.

 

Conclusions: We have found many significant differences in the GI

tissue gene expression profiles between vaccinated and unvaccinated

animals. These differences will be presented and discussed.

 

- - - -

 

/The authors and organizations are withholding comment or elaboration

until the full articles are published.

/

 

*

 

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//

 

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Is the proliferation of vaccinations really in your child's best interest?*

 

May 15, 2008

By Barbara Jamison, R.N.

For the News-Sentinel

http://www.news-sentinel.com/apps/pbcs.dll...ORIAL/805150318

 

All parents should review the list of routinely recommended vaccinations

for babies, toddlers and young children prior to giving consent. Read

the available information about each vaccine. Go online or to the public

library. Ask a friend, co-worker, nurse or doctor for in-depth

information regarding each vaccine. Ask questions such as: How dangerous

is the illness? Is my child likely to contract the illness? What are the

risks of the vaccine?

 

Vaccination against disease has been an ongoing process since the

smallpox inoculations in the late 1700s. At that time, the etiology of

common infectious diseases was unknown. Today in America, most people

have an excellent quality of food, water and proper sanitation. We

understand how disease is spread and have access to treatment.

 

It is time to take a new look at the need for specific vaccinations.

Vaccination is designed to benefit the public health. It is a

one-size-fits- all approach. Thus, the rural Midwestern baby receives the

same treatment as the crowded inner-city baby. Surely, the needs of

these babies are not the same.

 

Hepatitis B vaccine is recommended for men who have sex with men, IV

drug users and babies prior to hospital discharge after birth. This is

because the government wishes to avoid future cases of Hepatitis B.

Thus, all babies, regardless of the likelihood of exposure, are given

this injection. Does that seem appropriate to you? This same theory is

the reason for the recent push to vaccinate all 11- to 12-year-old

females against HPV (human papilloma virus), which is spread by sexual

contact. Another example: Hepatitis A is a contagious liver disease

spread through contaminated food and water. Children are not among the

high-risk group. Does your infant really need this shot?

 

A prudent approach would be to target a specific vaccine to specific

patient populations. The minimal recommended vaccination schedule

includes 60 doses --- some different strains of the same illness --- for

14 diseases by age 18 months. It is common for the shots to be bunched

in one day. If the baby is "off" schedule, your 15-month-old may receive

all the 12-18 monthly doses on the same office or clinic visit. Surely,

this must have some adverse effect on the immature immune system.

 

Some scientists correlate the proliferation of autoimmune disorders in

our society to multiple vaccinations at that very early age ---

illnesses such as asthma, diabetes, lupus, inflammatory bowel,

rheumatoid arthritis, allergies and certain cancers. Some medical

researchers and parents believe components of vaccine products cause or

did cause autism and other neurological disorders. All vaccines carry

risk and can be fatal. Indeed, a reaction is the expected outcome

necessary to provide immunity.

 

Scientists are continually making new vaccines and more

trivalent-polyvalen t forms. These are combinations of vaccines in one

dose. The more combinations, the less likely science will be able to

determine which vaccine causes a possible severe reaction in your child.

And the likelihood of severe reaction increases. Even today, we do not

know the true extent of problems post injection. The FDA estimates that

parents or physicians do not report 90 percent of adverse vaccine

reactions. Reactions such as seizures, high-pitched screaming, fever,

severe diarrhea, vomiting and shallow breathing are not reported. SIDS

will not be reported as a vaccine reaction unless it happens within 48

hours of the shot. Yet many vaccine responses occur within one to four

weeks.

 

The medical establishment equates refusal to vaccinate or choosing

partial vaccination as tantamount to child neglect. These parents are

often treated with contempt. Perhaps these parents are better parents.

Maybe it is best to allow viral contact between children. It is

impossible to prevent the spread of most viruses anyway. This would

encourage young immune systems to respond normally.

 

This letter is meant to increase parental awareness about childhood

vaccination and to encourage a more individual approach. Otherwise, the

price we pay is the loss of natural immunity to many diseases.

 

/Barbara Jamison is a registered nurse.

 

*

 

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in receiving the included information for research

and educational purposes.For more information go to:

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*Philly First In The Nation To Require Mercury Disclosures*

>

> By: JENNY DeHUFF, The Bulletin

> 05/14/2008

>

http://www.thebulletin.us/site/index.cfm?n...576361&rfi=

>

> Philadelphia - Freya Koss said she developed multiple sclerosis, lupus

> and other health problems from a silver dental filling containing

> mercury. She and several other consumer advocates and health

> professionals were at City Hall yesterday to tell their stories of

> cavity fillings gone wrong.

>

> The Pennsylvania Coalition for Mercury-Free Dentistry and Consumers for

> Dental Choice (CDC) stood in front of large signs warning of the

dangers

> of silver amalgam fillings - most notable for their high levels of the

> neurotoxin mercury.

>

> In December, Philadelphia City Council unanimously passed legislation

> backed by Councilwoman Blondell Reynolds Brown that requires

dentists to

> distribute patient brochures disclosing the dangers of silver amalgam

> fillings.

>

> "The textbooks don't tell us this," said Charlie Brown, spokesman for

> the CDC. "It is absurd to think nothing is damaged when a neurotoxin is

> placed an inch from someone's brain."

>

> "I quickly learned of the harrowing effects of mercury when an old

> filling was removed and a silver filling replaced it," said Ms. Koss,

> director of the Pennsylvania Coalition for Mercury-Free Dentistry.

> "Seven days later, I got sick."

>

> Don Robbins operates a mercury-free dentist practice out of Exton. He

> called himself one of the few dentists committed to informing patients

> of the risk of silver amalgam fillings. Holding a jar of dental mercury

> filling, Mr. Robbins pointed out the skull and crossbones icon on the

> label, warning that the substance is hazardous to children and to

handle

> the container with gloves and protective gear.

>

> "It's deeply disturbing what's going on in our profession," Mr. Robbins

> said. "Less than 60 percent of dentists in the U.S. belong to the

> American Dental Association (ADA). Silver fillings are 50 percent

> mercury. If you have two, three or more silver fillings, you are above

> the Environmental Protection Agency's (EPA) limit for mercury intake."

>

> Earlier in the day, consumers protested statements made by the

president

> of the Pennsylvania Dental Association. "No dentist places mercury in a

> patient's mouth," he was reported to have said.

>

> The alternatives to these types of fillings are typically white

> composite resin fillings, which are more commonly used today but don't

> last as long as silver fillings.

>

> Jenny DeHuff can be reached at jdehuff@...

>

> ©The Evening Bulletin 2008

>

> The material in this post is distributed without

> profit to those who have expressed a prior interest

> in receiving the included information for research

> and educational purposes.For more information go to:

> http://www4. law.cornell. edu/uscode/ 17/107.html

> http://oregon. uoregon.edu/ ~csundt/document s.htm

> If you wish to use copyrighted material from this

> email for purposes that go beyond 'fair use', you

> must obtain permission from the copyright owner*.*

>

 

 

Our results indicate the genotoxic and cytotoxic effect of TH in

cultured human peripheral blood lymphocytes at tested doses in

cultures with/without S9 fraction

 

1: Toxicol In Vitro. 2008 Jun;22(4):927- 34. Epub 2008 Feb 1.Click here

to read Links

Genotoxicity of thimerosal in cultured human lymphocytes with and

without metabolic activation sister chromatid exchange analysis

proliferation index and mitotic index.

Eke D, Celik A.

 

Mersin University, Faculty of Science and Letters, Department of

Biology, 33343 Mersin, Turkey.

 

Thimerosal is an antiseptic containing 49.5% of ethyl mercury that

has been used for years as a preservative in many infant vaccines and

in flu vaccines. Thimerosal is an organic mercurial compound used as a

preservative in biomedical preparations. In this study, we evaluated

the genotoxic effect of thimerosal in cultured human peripheral blood

lymphocytes using sister chromatid exchange analysis in culture

conditions with and without S9 metabolic activation. This study is the

first report investigating the genotoxic effects of thimerosal in

cultured human peripheral blood lymphocyte cells using sister

chromatid exchange analysis. An analysis of variance test (ANOVA) was

performed to evaluate the results. Significant induction of sister

chromatid exchanges was seen at concentrations between 0.2 and

0.6mug/ml of thimerosal compared with negative control. A significant

decrease (p<0.001) in mitotic index (MI) and proliferation index (PRI)

as well as an increase in SCE frequency (p<0.001) was observed

compared with control cultures. Our results indicate the genotoxic and

cytotoxic effect of TH in cultured human peripheral blood lymphocytes

at tested doses in cultures with/without S9 fraction