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Posted

As I continue on trapped without any medical support until Dr. L on Dec. 23, I decided to pick up my daughters records. I just looked back and saw that she was seen on 3/22/2010 for "walking pneumonia." I thought that was back last November. Anyhow, it says "??Mycoplasma Pneumonia" for the diagnosis. No blood was drawn, but she did take Zithromax 200/100 x 5 mL for 5 days. Her cough cleared up very quickly on that. But that is not when her tics skyrocketed. That might have been when she had one or two. It wasn't until the one-day fever on June 24 that the tics went from 2 or 3 to over a dozen. And they just continue to get more frequent, in spite of being treated with Augmentin for 9 days end of Sept. for staph Impetigo. The ocd had been there prior to June 24 too....

Don't want to get too excited about this, but could she still have an underlying infection of myco.p? without symptoms? otherwise healthy as a clam? also, i read that there is acute or chronic infection of myco. p, but you also have to consider an autoimmune response. How are those two things tested in case the infection is cleared?

thanks!

Posted

Zithromax is a good antibiotic to treat mycoplasma pneumonia, but that dose was low and only for 5 days. I think she should have had a larger dose for a longer time, so still having mycoplasma is very possible I think. The Augmentin she was on later in the summer would not have treated the mycoplasma.

 

Dr. T definitely knows all about treating mycoplasma pneumo in PANDAS kids and would most likely call you in (after a phone consult with him) zithromax or Biaxin (very similiar to zith but more anti-inflammatory properties).

 

You can do titers for mycoplasma pneumonia- I think IgA and IgG to see if it is a current infection or an old.

 

Colleen

Posted

Mycoplasma pneumoniae is ubiquitous and probably all of us have been exposed to it at some point. Elevated IgG means there is evidence of past (who knows when) exposure and possibly infection. An elevated IgM indicates a recent or present infection. Although everyone I have consulted regarding elevated Mycoplasma pneumoniae has admitted not knowing specifically the implications of elevated antibodies as related to PANDAS symptoms/tics, a couple of physicians have said that it can possibly be significant. The rest have said it's not a big deal.

 

I find it interesting that infections of Mp are on the rise according to the CDC.

 

I have come across a couple of published accounts of tics/ocd being associated with a Mycoplasma pneumoniae infection. As far as antibiotic treatment, the -mycin class of antibiotics is used. In addition, Nystatin, which is normally given for fungal infections, is effective against Mycoplasma, as this bacterium lacks a cell wall, as do fungal cells. My son was treated at the onset of his very first tic/ocd episode with Nystatin only, because the doc then thought he had intestinal fungal colonization. All tics/ocd disappeared within weeks. It didn't work as magically with subsequent episodes.

 

Our newest PANDAS doc (been through a few!) has told me that he believes many infectious entities can trigger a PANDAS episode in those kids who are prone to the problem, including strep and mycoplasma. My son only has residual ocd (so mild you wouldn't know it was there) and trichotillomania, which may be another form of ocd. He has been on biaxin, azithromycin, and now is on penicillin vk prophylactically and to try to rid the torment of the trichotillomania. He does have mycoplasma IgG of 6.7! Have not retested since April.

Posted (edited)

Mycoplasma pneumoniae is ubiquitous and probably all of us have been exposed to it at some point. Elevated IgG means there is evidence of past (who knows when) exposure and possibly infection. An elevated IgM indicates a recent or present infection. Although everyone I have consulted regarding elevated Mycoplasma pneumoniae has admitted not knowing specifically the implications of elevated antibodies as related to PANDAS symptoms/tics, a couple of physicians have said that it can possibly be significant. The rest have said it's not a big deal.

 

I find it interesting that infections of Mp are on the rise according to the CDC.

 

I have come across a couple of published accounts of tics/ocd being associated with a Mycoplasma pneumoniae infection. As far as antibiotic treatment, the -mycin class of antibiotics is used. In addition, Nystatin, which is normally given for fungal infections, is effective against Mycoplasma, as this bacterium lacks a cell wall, as do fungal cells. My son was treated at the onset of his very first tic/ocd episode with Nystatin only, because the doc then thought he had intestinal fungal colonization. All tics/ocd disappeared within weeks. It didn't work as magically with subsequent episodes.

 

 

Our newest PANDAS doc (been through a few!) has told me that he believes many infectious entities can trigger a PANDAS episode in those kids who are prone to the problem, including strep and mycoplasma. My son only has residual ocd (so mild you wouldn't know it was there) and trichotillomania, which may be another form of ocd. He has been on biaxin, azithromycin, and now is on penicillin vk prophylactically and to try to rid the torment of the trichotillomania. He does have mycoplasma IgG of 6.7! Have not retested since April.

 

you have given me an "aha" moment!!!!!!!!

Edited by Fixit
Posted

FixIt--please do share your moment:)

I'm wondering who the new doc is that thinks many infectuious entities can trigger a pandas episode......

 

 

Mycoplasma pneumoniae is ubiquitous and probably all of us have been exposed to it at some point. Elevated IgG means there is evidence of past (who knows when) exposure and possibly infection. An elevated IgM indicates a recent or present infection. Although everyone I have consulted regarding elevated Mycoplasma pneumoniae has admitted not knowing specifically the implications of elevated antibodies as related to PANDAS symptoms/tics, a couple of physicians have said that it can possibly be significant. The rest have said it's not a big deal.

 

I find it interesting that infections of Mp are on the rise according to the CDC.

 

I have come across a couple of published accounts of tics/ocd being associated with a Mycoplasma pneumoniae infection. As far as antibiotic treatment, the -mycin class of antibiotics is used. In addition, Nystatin, which is normally given for fungal infections, is effective against Mycoplasma, as this bacterium lacks a cell wall, as do fungal cells. My son was treated at the onset of his very first tic/ocd episode with Nystatin only, because the doc then thought he had intestinal fungal colonization. All tics/ocd disappeared within weeks. It didn't work as magically with subsequent episodes.

 

 

Our newest PANDAS doc (been through a few!) has told me that he believes many infectious entities can trigger a PANDAS episode in those kids who are prone to the problem, including strep and mycoplasma. My son only has residual ocd (so mild you wouldn't know it was there) and trichotillomania, which may be another form of ocd. He has been on biaxin, azithromycin, and now is on penicillin vk prophylactically and to try to rid the torment of the trichotillomania. He does have mycoplasma IgG of 6.7! Have not retested since April.

 

you have given me an "aha" moment!!!!!!!!

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