Staph and PANDAS

[jstone]

I apologize in advance for what I feel could be a very newbie question, but is anyone aware of any studies linking Staph related infections/autoimmue responses to PANDAS or OCD symptoms?

[sf_mom]

I am aware of one PANDAS child that had a abscess removed and they found staph.

[jstone]

SF Mom,

So it seems to be the minority of the cases and unless you disagree, I assume that if Staph was somehow more involved with PANDAS or other OCD / tic related disorders that Swedo et al would have already studied it and addressed that. One consideration is that if the immune system of our kids is compromised, it probably means that any micro-organism has an easier time successfully attacking our kids' bodies. I am sure an immunologist could explain why Strep and its antibodies has been more successful cross reacting with the neurons in the brain. Thanks for your reply.

[sf_mom]

In the biopsies of tonsils, abscesses in sinuses or serotyped cultures, etc of PANDAS children.... the following has been found:

 

- epikenella corrodens

- strep A, B, F, etc.

- staph

- haemophilus influenzae (loves to make love to strep is my understanding)

 

Others with co-infections of lyme, mycoplasma and still others have a history of Kawasaki's.

 

I've posted this before but feel its important. The strep pyogenes consists of strep A M-protein strains: M1, M11, M18 all RF strains (M1 being to most predominate in the US right now).

 

Group A streptococci typically have a capsule composed of hyaluronic acid and are beta-hemolytic, which is true for Streptococcus pyogenes.[1] Beta-hemolytic streptococci produce a toxin that forms a clear zone of hemolysis on blood agar, demonstrating its ability to destroy red blood cells. This hemolysis is attributed to toxins formed by Group A streptococci called streptolysins. Streptolysins can destroy not only red blood cells, but also the white blood cells responsible for fighting off bacteria and disease, as well as other body cells.[2]

 

http://pyogenesgonewild.com

 

My twins both have low RBC and WBC.

[Stephanie2]

Very interesting, SF Mom. My 2 year old also has low WBC. I will have to bring this to the docs attention and see what he thinks.

 

Anyway, both of my boys recently had staph (oh, and so did I ). My 5 yo still has it in his gut (per stool analysis). I do feel that it caused my 2 yo's worst pandas episode yet.

 

Stephanie

In the biopsies of tonsils, abscesses in sinuses or serotyped cultures, etc of PANDAS children.... the following has been found:

 

- epikenella corrodens

- strep A, B, F, etc.

- staph

- haemophilus influenzae (loves to make love to strep is my understanding)

 

Others with co-infections of lyme, mycoplasma and still others have a history of Kawasaki's.

 

I've posted this before but feel its important. The strep pyogenes consists of strep A M-protein strains: M1, M11, M18 all RF strains (M1 being to most predominate in the US right now).

 

Group A streptococci typically have a capsule composed of hyaluronic acid and are beta-hemolytic, which is true for Streptococcus pyogenes.[1] Beta-hemolytic streptococci produce a toxin that forms a clear zone of hemolysis on blood agar, demonstrating its ability to destroy red blood cells. This hemolysis is attributed to toxins formed by Group A streptococci called streptolysins. Streptolysins can destroy not only red blood cells, but also the white blood cells responsible for fighting off bacteria and disease, as well as other body cells.[2]

 

http://pyogenesgonewild.com

 

My twins both have low RBC and WBC.

[matis_mom]

In the biopsies of tonsils, abscesses in sinuses or serotyped cultures, etc of PANDAS children.... the following has been found:

 

- epikenella corrodens

- strep A, B, F, etc.

- staph

- haemophilus influenzae (loves to make love to strep is my understanding)

 

Others with co-infections of lyme, mycoplasma and still others have a history of Kawasaki's.

 

I've posted this before but feel its important. The strep pyogenes consists of strep A M-protein strains: M1, M11, M18 all RF strains (M1 being to most predominate in the US right now).

 

Group A streptococci typically have a capsule composed of hyaluronic acid and are beta-hemolytic, which is true for Streptococcus pyogenes.[1] Beta-hemolytic streptococci produce a toxin that forms a clear zone of hemolysis on blood agar, demonstrating its ability to destroy red blood cells. This hemolysis is attributed to toxins formed by Group A streptococci called streptolysins. Streptolysins can destroy not only red blood cells, but also the white blood cells responsible for fighting off bacteria and disease, as well as other body cells.[2]

 

http://pyogenesgonewild.com

 

My twins both have low RBC and WBC.

This is very interesting... my doc was saying we did not think I had an active infection because my WBC was not elevated. My PANDAS son's CBC always looks normal.

So maybe I should challenge that...