Kawasaki disease

[kim]

http://www.pediatricsupersite.com/view.aspx?rid=63822

 

 

The researchers determined that development of Kawasaki disease in later childhood was connected to the following factors:

 

Maternal age of 35 years and older (OR=1.65; 95% CI, 1.20-2.27)

Mother born outside of the United States (OR=1.36; 95% CI, 1.06-1.76).

Maternal group B streptococcal colonization (OR=0.52; 95% CI, 0.26- 0.97).

[Stephanie2]

Can someone please tell me how kawasaki relates to pandas? My brother had kawasake at approx the age of 5. Both of my boys have pandas and both of my brother's daughters have had pandas exacerbations before. I also believe that our cousin's little boy has pandas (well he has the tics and OCD, but my cousin is not interested in finding out if it is pandas related...??!!).

 

Is kawasaki caused by strep? I don't remember that being part of the picture when he had kawasaki (I was 10 at the time so maybe I missed that part). I just know that they had to monitor his heart for a few months.

 

Stephanie

 

http://www.pediatricsupersite.com/view.aspx?rid=63822

 

 

The researchers determined that development of Kawasaki disease in later childhood was connected to the following factors:

 

Maternal age of 35 years and older (OR=1.65; 95% CI, 1.20-2.27)

Mother born outside of the United States (OR=1.36; 95% CI, 1.06-1.76).

Maternal group B streptococcal colonization (OR=0.52; 95% CI, 0.26- 0.97).

[kim]

Stephanie,

 

Do you know how to search SFmom's posts? She has the best info on the possible Kawasaki connection.

 

I think many of us are searching for the connection to illness that seem to mimick PANDAS symtoms. MycoP, Lyme, etc.

It's very confusing for parents with kids that seem to have no known strep history (SFmom points out that Kawasacki has been linked to strep in at least one study, I believe) or have exacerbations with other illness.

 

Your remarks are interesting, regarding family members and your brother''s illness with Kawasaki

Edited May 5, 2010 by kim

[sf_mom]

Stephanie: In our case, friend's son ARF phase at playdate in 2007, week later DS1 became very ill but seemed recovered on his own, week later DS2 very ill, hospitalized for six days and diagnosed with Kawasaki's. ALL FIVE children who attended playdate have elevated CaM Kinase in PANDAS range and clinical presentation:

 

1. Adrian (147 CAM - Friend's son)

2. PJ (127 CAM - Friend's boyfriend's son) also positive for strep at playdate

3. Corsa DS1 (127 CAM - blood draw shortly after steroids so possibly lowered score)

4. Romy DS2 (148 CAM)

5. Bena DD (157 CAM)

 

All the children have deficiencies in strep pneumo titers. My children are not full biologically related.

 

Kawasaki's share 93 symptoms with RF. Unfortunately, children with Kawasaki's do not have raised titers or positive cultures. The study attached links to Strep Pyogenes.... same strains for RF.

 

http://www.springerlink.com/content/l34qj830548q4q46/

[Stephanie2]

So are you saying that your DS2 developed kawasaki and then went on to develop pandas related to that incident? So either there was really bad strep, or coincidentally everyone was susceptible or pandas is a lot more common than ppl think. I know that my boys and my neices all exacerbated around the same time last year and both of my sons were positive for strep around that time (and frequently interacted with my neices). So either it was the type of strep or it was the genetic susceptibility in our case. I always assumed genetics in our case, but now I wonder...

 

Stephanie

 

 

 

Stephanie: In our case, friend's son ARF phase at playdate in 2007, week later DS1 became very ill but seemed recovered on his own, week later DS2 very ill, hospitalized for six days and diagnosed with Kawasaki's. ALL FIVE children who attended playdate have elevated CaM Kinase in PANDAS range and clinical presentation:

 

1. Adrian (147 CAM - Friend's son)

2. PJ (127 CAM - Friend's boyfriend's son) also positive for strep at playdate

3. Corsa DS1 (127 CAM - blood draw shortly after steroids so possibly lowered score)

4. Romy DS2 (148 CAM)

5. Bena DD (157 CAM)

 

All the children have deficiencies in strep pneumo titers. My children are not full biologically related.

 

Kawasaki's share 93 symptoms with RF. Unfortunately, children with Kawasaki's do not have raised titers or positive cultures. The study attached links to Strep Pyogenes.... same strains for RF.

 

http://www.springerlink.com/content/l34qj830548q4q46/

[matis_mom]

http://www.pediatricsupersite.com/view.aspx?rid=63822

 

 

The researchers determined that development of Kawasaki disease in later childhood was connected to the following factors:

 

Maternal age of 35 years and older (OR=1.65; 95% CI, 1.20-2.27)

Mother born outside of the United States (OR=1.36; 95% CI, 1.06-1.76).

Maternal group B streptococcal colonization (OR=0.52; 95% CI, 0.26- 0.97).

Geee, my two youngest have all three!!! Interesting though. I wonder if we could get something similar for PANDAS...