Ticcing again!

[melanie]

Well most of you know our story Danny 15 4 weeks post IVIG still no antibiotics.We are seeing the infectious disease Md Tuesday .hopefully we will continue treatment with Antibiotics or IV monthly .If not I will try something Else.Danny's has been ticking alot his tics are curses so they are very obvious.When he hears people speak if you stammer he hears what he calls stuttering ,We had had hearing tests etc. 2 weeks post IV no ticcing no cursing life is wonderful.oCD no comparison pre IV like nothing .His OCD was WW11 but like Hitler and well ,,Now its not even intrusive .Behaviors pre IV horrible.Started risperdal in end of June .Much better but not like its been for the past month .Hes been sooooo great .School(special ed school) perfect days,His therapist is amazed at his progress too,so I know its not just me. The only thing we have done is added zoloft so I'm thinking maybe ? It could be a coincidence?sp) I'm not happy !!! Help maybe it will never get better ....

 

 

Melanie

[sf_mom]

He needs to be on antibiotics to prevent further exposure or process starts all over again. Have you checked his STREP PNEUMOCOCCAL ANTIBODY TITER yet to see if he has the ability to fight off ANY type of strep infection. Do you know if he has a deficiency in his subclasses? If not, have those checked with an immunologist and possibly pursue further IVIG for immune deficiencies.

 

Although our son has had some tic free days... I do occasionally see them crop back up and he is almost 3 weeks post IVIG.

[faith]

melanie,

what are you exactly saying? that he started tics again? which ones? when did you add the zoloft? could that be a side effect of the zoloft? I think that may be one of the side effects. What "coincidence" are you referring to? that the zoloft helped him or hindered him? Why did they add a med if you were in the midst of other treatment?

[melanie]

He needs to be on antibiotics to prevent further exposure or process starts all over again. Have you checked his STREP PNEUMOCOCCAL ANTIBODY TITER yet to see if he has the ability to fight off ANY type of strep infection. Do you know if he has a deficiency in his subclasses? If not, have those checked with an immunologist and possibly pursue further IVIG for immune deficiencies.

 

Although our son has had some tic free days... I do occasionally see them crop back up and he is almost 3 weeks post IVIG.

 

 

We are seeing a infectious disease md tuesday is that like the same as a immunologist

[colleenrn]

Is he on antibiotics now? If not, when was he last on them?

[peglem]

Well most of you know our story Danny 15 4 weeks post IVIG still no antibiotics.We are seeing the infectious disease Md Tuesday .hopefully we will continue treatment with Antibiotics or IV monthly .If not I will try something Else.Danny's has been ticking alot his tics are curses so they are very obvious.When he hears people speak if you stammer he hears what he calls stuttering ,We had had hearing tests etc. 2 weeks post IV no ticcing no cursing life is wonderful.oCD no comparison pre IV like nothing .His OCD was WW11 but like Hitler and well ,,Now its not even intrusive .Behaviors pre IV horrible.Started risperdal in end of June .Much better but not like its been for the past month .Hes been sooooo great .School(special ed school) perfect days,His therapist is amazed at his progress too,so I know its not just me. The only thing we have done is added zoloft so I'm thinking maybe ? It could be a coincidence?sp) I'm not happy !!! Help maybe it will never get better ....

 

 

Melanie

 

I think you're right to look at the meds. I'm wondering why the zoloft was added, since it sounds like he was doing so well. Wanted to share my experience with risperdal. It worked pretty good (not great though, too much going on w/ the PANDAS to know exactly what was doing what) at 1st, maybe because it helped her to sleep better? After a few months though, the effectiveness seemed to wear off, and a month or so later it actually seemed to be increasing rages and irritation- taking her off of it at that point really improved things. As you probably know, risperdal is a dopamine blocker. Zoloft does have some dopamine re-uptake inhibition effects as well as being an SSRI...

Sure hope you get things straightened out for your guy and this ticcing doesn't get worse!

[melanie]

Is he on antibiotics now? If not, when was he last on them?

He hasnt been on antibiotocs since like june

[melanie]

Well most of you know our story Danny 15 4 weeks post IVIG still no antibiotics.We are seeing the infectious disease Md Tuesday .hopefully we will continue treatment with Antibiotics or IV monthly .If not I will try something Else.Danny's has been ticking alot his tics are curses so they are very obvious.When he hears people speak if you stammer he hears what he calls stuttering ,We had had hearing tests etc. 2 weeks post IV no ticcing no cursing life is wonderful.oCD no comparison pre IV like nothing .His OCD was WW11 but like Hitler and well ,,Now its not even intrusive .Behaviors pre IV horrible.Started risperdal in end of June .Much better but not like its been for the past month .Hes been sooooo great .School(special ed school) perfect days,His therapist is amazed at his progress too,so I know its not just me. The only thing we have done is added zoloft so I'm thinking maybe ? It could be a coincidence?sp) I'm not happy !!! Help maybe it will never get better ....

 

 

Melanie

 

I think you're right to look at the meds. I'm wondering why the zoloft was added, since it sounds like he was doing so well. Wanted to share my experience with risperdal. It worked pretty good (not great though, too much going on w/ the PANDAS to know exactly what was doing what) at 1st, maybe because it helped her to sleep better? After a few months though, the effectiveness seemed to wear off, and a month or so later it actually seemed to be increasing rages and irritation- taking her off of it at that point really improved things. As you probably know, risperdal is a dopamine blocker. Zoloft does have some dopamine re-uptake inhibition effects as well as being an SSRI...

Sure hope you get things straightened out for your guy and this ticcing doesn't get worse!

Do you think its the zoloft?"

[EAMom]

zoloft (sertraline) can cause tics. Here is one case report: http://www.highbeam.com/doc/1P3-1219545771.html

 

I agree with peglem, why the zoloft? When did he start that? It seems really odd to start that when he's just had IVIG since you won't know if a change is from the IVIG or the Zoloft.

 

Also, be aware that some SSRI's (including Zoloft) will give you nasty nasty withdrawal symptoms if you stop taking them too quickly...you have to wean off really slowly.

 

Here's one article...there is more if you google:

http://depression.emedtv.com/zoloft/zoloft-withdrawal.html

[peglem]

Do you think its the zoloft?"

 

I think there is too much going on to get a clear indication. The IVIG should have helped with the messed up dopamine in his basal ganglia, if it worked. But, then you have risperdal blocking some dopamine...so then it'd be hard to tell the effect of the IVIG. Then throwing zoloft in there increases the amount of time that dopamine is stimulating receptors...it all gets kind of mirky.

 

I wonder if he needed to come off the risperdal after IVIG, and it was the risperdal in the face of basal ganglia corrections (from IVIG) that was causing whatever prompted the doc to add zoloft. I feel like I'm not saying this right, but I think after the IVIG, I'd want to see how he does w/o external dopamine manipulators.

 

This is all based on my own supposition....just brainstorming ideas.

[melanie]

Do you think its the zoloft?"

 

I think there is too much going on to get a clear indication. The IVIG should have helped with the messed up dopamine in his basal ganglia, if it worked. But, then you have risperdal blocking some dopamine...so then it'd be hard to tell the effect of the IVIG. Then throwing zoloft in there increases the amount of time that dopamine is stimulating receptors...it all gets kind of mirky.

 

I wonder if he needed to come off the risperdal after IVIG, and it was the risperdal in the face of basal ganglia corrections (from IVIG) that was causing whatever prompted the doc to add zoloft. I feel like I'm not saying this right, but I think after the IVIG, I'd want to see how he does w/o external dopamine manipulators.

 

This is all based on my own supposition....just brainstorming ideas.

 

 

I cant read that zoloft article..I googled it and cant find where it says it can causse tics?

[EAMom]

You can't see the whole article without paying...here's what you can see:

 

 

Article: Sertraline caused tics in a child with obsessive-compulsive disorder

Article from:Journal of Pediatric Neurology Article date:January 1, 2006 Author:Desarkar, Pushpal; Sinha, Vinod Kumar CopyrightCopyright Journal of Pediatric Neurology 2006. Provided by ProQuest LLC. (Hide copyright information)

 

 

The selective serotonin reuptake inhibitor (SSRI) sertraline is generally well-tolerated and is rarely associated with any movement disorder with its use. However, recent neurophysiological findings increasingly reveal alteration of dopaminergic neurotransmission by the SSRIs leading to occurrence of certain 'dopaminedependent' side effects [1]. We report a case of reversible motor tics caused by sertraline.

 

A 12-year-old boy with no contributory past or family history was brought for consultation with six months history suggestive of obsessive-compulsive disorder (OCD) inadequately controlled with 100 mg of sertraline, which he had been receiving for past one month. We hiked the dose of ...

[melanie]

You can't see the whole article without paying...here's what you can see:

 

 

Article: Sertraline caused tics in a child with obsessive-compulsive disorder

Article from:Journal of Pediatric Neurology Article date:January 1, 2006 Author:Desarkar, Pushpal; Sinha, Vinod Kumar CopyrightCopyright Journal of Pediatric Neurology 2006. Provided by ProQuest LLC. (Hide copyright information)

 

 

The selective serotonin reuptake inhibitor (SSRI) sertraline is generally well-tolerated and is rarely associated with any movement disorder with its use. However, recent neurophysiological findings increasingly reveal alteration of dopaminergic neurotransmission by the SSRIs leading to occurrence of certain 'dopaminedependent' side effects [1]. We report a case of reversible motor tics caused by sertraline.

 

A 12-year-old boy with no contributory past or family history was brought for consultation with six months history suggestive of obsessive-compulsive disorder (OCD) inadequately controlled with 100 mg of sertraline, which he had been receiving for past one month. We hiked the dose of ...

 

 

I have to check the start dates with the zoloft and ill cut the night dose in 1/2 see if i notice anything Im going to pull my hair out!!!!!!

[EAMom]

I have to check the start dates with the zoloft and ill cut the night dose in 1/2 see if i notice anything Im going to pull my hair out!!!!!!

 

Watch out for withdrawals...you might have to wean really really slowly...3/4 dose might be better to start. When we were on Lexapro (also an SSRI) withdrawal was really tough...

[Kayanne]

I agree with EAMom, my husband took zoloft, and you need to be very slow and conservative...It wouldn't hurt to put in a call to the doctor for specific instructions on weaning.