michele Posted August 20, 2007 Report Posted August 20, 2007 Michele, Bumped this thread for you. In response to the question about behavior issues (on the "testing thread), you might want to try epsom salt baths. Kim, I did try the epsom salt baths and he loves them. It seems to help with getting him down to sleep at night. He seems more relaxed. Thanks. Michele
Lin Posted October 15, 2007 Report Posted October 15, 2007 I'm new to the forum and we've been trying different protocols for our son (who is now 20). He has high strep antibodies, tics, ocd, anxiety, panic...... After reading about the antibodies attacking the basal ganglia - what is the protocol to stop the destruction and how do we repair the basal ganglia? I see that antibiotics are in order. We've tried many products, but haven't yet targeted the root of the problem. I tried to going to the link you entered, but page does not display - any help here? Also, any comments on the zapper as it is suppose to kill viruses, bacteria, and parasites? Dr. Amy Yasko on Strep http://www.autismanswer.com/articles/yasko...citotoxins.html Blood Type/Streptococcal Infection The A-B-O system for blood typing is dependent on the blood group antigens that are expressed on the outer surface of an individuals' red blood cells. Those with blood type A have NAC-gal (n-acetyl galactosamine) as the predominant blood group antigen, and those with type B have galactose as their primary antigen. Those with blood type O have fucose as a predominant antigenic determinant on their red blood cells. In addition, to a lesser extent the NAC-glu (n-acetyl glucosamine) antigen would be accessible to the immune system in those with blood type O due to the limited carbohydrate antigen on the surface of type O red blood cells. It is necessary for the body to discern the difference between self and non-self, and to prevent the immune system from attacking self. As a consequence of this "tolerance" to self, those with blood type O would have a higher tolerance to NAC-glu, and would not have as high a natural tolerance to NAC-gal and galactose as would those with blood types of A or B. Similarly, those with blood type A would have a higher "self-tolerance" to NAC-gal. The major carbohydrate antigenic determinants on the surface of the streptococcus bacteria are predominantly NAC-glu and NAC-gal. As a consequence, persons with blood type O and type A would have an initial greater natural tolerance to infection from streptococcal bacteria. After repeated exposure to the streptococcus bacterium, an immune response would finally be mounted, and targeted against the antigenic determinants on the bacterium. When this happens the immune cells of the body inadvertently launch an autoimmune attack upon body tissue with antigenic determinants that are similar to the antigen on the surface of the streptococci. This reaction to the NAC-glu and NAC-gal on the surface of the streptococci could also lead to an autoimmune type reaction against the NAC-glu/gal in the GI tract. This process has been recognized since the middle 1980's and is known as molecular mimicry. The excessive shedding of NAC-glu and NAC-gal, otherwise referred to as GAG has been described and well characterized by others. Suffice to say that the shedding of GAGs in the GI tract is enhanced with immune activation and inflammation. Following infection and/or inflammation, the body would need to replace GAGs that have been shed, as well as to sulfate them. If there is a sulfur deficiency in the body, this would lead to undersulfated GAGs in the GI tract along with the deficiency of other sulfur related proteins in the body. Nitric oxide has been shown to inhibit sulfation of GAGs. High levels of nitric oxide are a consequence of excitotoxin damage. Generally, bacteria elicit a B cell mediated immune response, and viruses elicit a T cell mediated immune response. However, a large number of extracellular toxins are elaborated by streptoccocci, all of which have the ability to nonspecifically stimulate T cells. Therefore once an immune response is mounted against streptococcus it would involve both T cell and B cells resulting in a major inflammatory reaction. One particular extracellular enzyme produced by streptococcus is a sulfhydryl protease. This protease is capable of cleaving sulfhydryl groups and may lead to a deficiency of available sulfur containing moieties in the body following streptococcal infection. These sulfhydryl groups are involved in the binding and elimination of heavy metals in the body. Streptococcal infection is also known to lead to elevated levels of the inflammatory cytokines NFKB and TNF alpha. In addition, the level of TNF alpha is inversely correlated with glutathione levels. Consequently, high TNF alpha levels as a result of streptococcal infection would result in decreases in glutathione levels. Streptococcal infection is also associated with a wide variety of behavioral disturbances. High levels of TNF alpha (as a result of streptococcal infection) have been implicated in Tourettes syndrome, facial tics, obsessive compulsive behavior, and schizophrenia. On a related note, lithium (the most popular prescription drug for treating the mood swings associated with manic, or bipolar depression) has been demonstrated to act by protecting the brain from over stimulation by glutamate. Excessive levels of glutamate have also been implicated in drug craving and in addictive behavior. Consequently, the net results of streptococcal infection are depletion of Vitamin K levels, decreased glutathione levels, decreased sulfhydryl protein levels, over stimulation of the immune system, increased TNF alpha levels (which trigger OCD, facial tics, etc.), potential autoimmune responses and inflammatory reactions against the GAGs in the GI tract.
kim Posted October 16, 2007 Report Posted October 16, 2007 Hi Lin, Welcome! You say that you have tried products? Does that mean antibiotics? We have so many posts here from parents that are really knowledgable about PANDAS! Most are treating with antibiotics, probiotics, vit and or mineral supp, diet restrictions etc. The post you quoted, is from Dr. Amy Yasko. I know that link is no longer active, and I wish it were. Anyway, she has a web group. Lot's of wonderful info. http://www.ch3nutrigenomics.com/phpBB2/ind...69514449e8233c0 Under the tread titled "Virus, Vaccines, Infections, Mercury, & Antibiotics," she has a post explaining that most kids with chronic viral issues have problems with heavy metals, but bacterial infections are more related to aluminum retention. She refers to the CDSA (comprehensive diagnostic stool anaylsis) where kids show high strep repeatedly. Many posts showing strep at 4+, suggesting strep in the gastro tract. Interesting stuff, that is not really discussed elsewhere, that I know of. I hope you find some answers here to help your son, Lin. We have many wonderful people here willing to share their experience.
kim Posted October 17, 2007 Report Posted October 17, 2007 I don't know if this is the thread where quick strep test was discussed, but wondered if there was new tech. in regards to detecting strep with home strips. This article is from 05, so maybe. I could see using a home test to detect, but would want to be careful on ruling it out, this way http://www.medicalnewstoday.com/articles/24454.php Still have to swab those tonsils to test for strep Main Category: Ear, Nose and Throat News Article Date: 16 May 2005 - 9:00 PDT Thought this was a cool list (posted on autism_info) Not sure the of the source. There was one posted there for staph too, if anyone is interested. A mom posted her notes from different speakers at recent DAN conference, interesting strep was mentioned quite a bit. Description Detrimental Streptococcus refers to those strains of Streptococcus Bacteria that are detrimental to human health. Note that Streptococcus Bacteria can be either beneficial or detrimental depending on its environment and circumstances. This topic refers only to those Streptococcus Bacteria that are regarded as "harmful". These Substances may Inhibit Detrimental Streptococcus Bacteria Proteins Royalisin may inhibit Detrimental Streptococcus Bacteria. references Vitamins Vitamin C may help to prevent infections from Detrimental Streptococcus species. references These Foods/Herbs may Inhibit Detrimental Streptococcus Bacteria Bee Foods Royal Jelly may inhibit Detrimental Streptococcus Bacteria (due to the Royalisin content of Royal Jelly). references Herbs Oregano Oil (applied topically or ingested orally) may inhibit (and may sometimes kill) many types of Detrimental Streptococcus Bacteria. Usnea may inhibit Detrimental Streptococcus Bacteria (due to the Usnic Acid content of Usnea). [more info] Vegetables Garlic may inhibit Detrimental Streptococcus Bacteria. references Toxic Effects of Detrimental Streptococcus Bacteria Immune System Rheumatic Fever may occur as a sequel to infections caused by Streptococcus Bacteria. Respiratory System Infection by Detrimental Streptococcus Bacteria may cause Pharyngitis (Sore Throat) - when Streptococcus Bacteria are the cause of Pharyngitis the condition is known as Streptococcal Throat (or Strep Throat). Infection by Detrimental Streptococcus Bacteria may cause Tonsillitis. Types of Detrimental Streptococcus Bacteria Streptococcus bovis Streptococcus equinus Streptococcus faecalis Streptococcus mutans Streptococcus pneumoniae Streptococcus pyogenes Streptococcus sanguis Streptococcus sobrinus
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