matis_mom Posted February 23, 2011 Report Posted February 23, 2011 So my 7yo ds and my 8yo dd had Scarlet Fever last Monday. Positive on the swab, started Cefprozil (pediatrician thought it would be better than Amoxicillin). After a week on that, my son is still not feeling well. So I took him back in today, and one side of his throat still looks red, and there is a swollen lymph node on that side. Rapid is negative, but they sent for culture. The pediatrician gave him Cipro, 250mg twice daily. Now, I'm all for erradicating this thing, but I am a bit concerned about he possible side-effects of Cipro. Incidentally, I was on it not that long ago for pseudomonas, which tested resistant to most abxs. This was in my tonsils, so it's not unlikely that my son would have it too, but again, when I read about tendon damage and the possibility of C. Difficile, well, does my 7yo really need it, or could we try something else??? Thanks!
Phasmid Posted February 23, 2011 Report Posted February 23, 2011 First, any antibiotic can cause an overgrowth of C. diff. Even the antibiotic specifically FOR C. diff. has been associated (in the literature) with overgrowth of C. diff. My biggest concern, if I were in your place, would be the adverse psych. effects of Cipro, being in the class of antibiotics that it is, namely the flouroquinolones. I took Cipro for an infection one time and had a panic attack. I did the same with Avelox, but MUCH more severe (like some of your kids, I could not leave my husband's side, terrified of who knows what, but completely anxiety-wrought). Then, my doc said, "Oh, yeah, this class of antibiotics is associated with anxiety attack." They don't know why these drugs have this side effect. Not a reason to NOT take it, if that is what is prescribed, but just something to watch for! You will know immediately if there is an issue with this med.!
matis_mom Posted February 23, 2011 Author Report Posted February 23, 2011 (edited) First, any antibiotic can cause an overgrowth of C. diff. Even the antibiotic specifically FOR C. diff. has been associated (in the literature) with overgrowth of C. diff. My biggest concern, if I were in your place, would be the adverse psych. effects of Cipro, being in the class of antibiotics that it is, namely the flouroquinolones. I took Cipro for an infection one time and had a panic attack. I did the same with Avelox, but MUCH more severe (like some of your kids, I could not leave my husband's side, terrified of who knows what, but completely anxiety-wrought). Then, my doc said, "Oh, yeah, this class of antibiotics is associated with anxiety attack." They don't know why these drugs have this side effect. Not a reason to NOT take it, if that is what is prescribed, but just something to watch for! You will know immediately if there is an issue with this med.! Well, thanks for the warning! Ds has been moody lately, I would even say depressed. So, of course, I'm always watching out for any sign of PANDAS (he is NOT my PANDAS child -please God, not him too! ) and making sure everyone is strep-free. Now I won't know which is which is he starts getting all anxious and clingy! Edited February 23, 2011 by mati's mom
matis_mom Posted February 23, 2011 Author Report Posted February 23, 2011 Well, I guess I'll be calling the pediatrician in the morning... this is what I found on Cipro... Fluoroquinolones are not licensed by the U.S. FDA for use in children due to the risk of fatalities as well as permanent injury to the musculoskeletal system, with two exceptions. Ciprofloxacin is being licensed for the treatment of complicated urinary tract infections and pyelonephritis due to Escherichia coli, and inhalational anthrax (postexposure), and levofloxacin was recently licensed for the treatment of inhalational anthrax (postexposure). However, the fluoroquinolones are licensed to treat lower respiratory infections in children with cystic fibrosis in the UK. Within the studies submitted in response to a Pediatric Written Request (ciprofloxacin, circa 2004), the rate of atrophy was reported to be 9.3%.[61] Within the BPCA Pediatric Studies Summary for ciprofloxacin,[61] it was stated that the overall incidence of adverse events at six weeks was 41%. This would be consistent with the safety profile found with the other fluoroquinolones studied in the pediatric population. As such, the current ban on the use of the fluoroquinolones in the pediatric population is both reasonable and supported by various clinical studies. The most recent long term study, BAY 0 9867 Cipro Pediatric Use Study (QUIP), which followed pediatric patients from 1999–2008,[62] supports the current expert opinion that the risk of permanent injury continues to outweigh the potential benefits of ciprofloxacin therapy in the pediatric population. Within the United States, the FDA has stated it is their intention to pursue the licensing of the fluoroquinolones for pediatric use in spite of the evidence presented at that 62 Meeting of the Anti-Infective Drugs Advisory Committee that the fluoroquinolones cause irreversible joint damage in the pediatric population.[63]
momofgirls Posted February 23, 2011 Report Posted February 23, 2011 just a little caution on the cipro...if you use it do not give ibruprophrin. They are not to be used together.
melanie Posted February 23, 2011 Report Posted February 23, 2011 Why no iP? Danny gets celebrex with cipro
Fixit Posted February 23, 2011 Report Posted February 23, 2011 thanks for posting this... not that we are using it..but if presented, will decline.
matis_mom Posted February 23, 2011 Author Report Posted February 23, 2011 Why no iP? Danny gets celebrex with cipro Melanie, So your child is taking Cipro? It would give me some reassurance to hear of others who are safely taking it. My PANDAS son took it after tonsillectomy, but it was only for 5 dyas. If you wouldn't mind sharing dosage/duration please? I am scared to death of some kind of super-bug living in my son's tonsils, and I'm also scared to death of the possible side-effects.
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