anyone have vomiting post ivig?

[norcalmom]

Someone from Lyme board pointed out that my son's reaction after switching antibiotics might be a herx. First, I have to say, I'm not even sure if I BELEIVE in herxing. I thought, no, the side effects listed for the drug (doryx) say that vomiting/nausea is a side effect.

 

But then, watching my son vomit, I had a flashback to 3 days post ivig. Violent vomiting - for 8-10 hours, almost every hour like clockwork. This morning he's now vomited 3 times in 4 hours.

 

I don't think its the antibiotic causing nausea, which would happen within a couple hours of taking it. Its been 12 hours since his last dose, so it isn't in his stomach. AND he has been taking it for almost 3 days with NO nausea at all...so it just doesn't seem like it is that particular side effect from what I've read.And No, there is no chance it is the flu. The only thing he's doing is vomiting. He's fine for an hour, and then vomits, and fine for another hour til the bile builds up. No one else has flu either.

 

The timing is almost exactly the same. He began vomiting approx77 hours after first does of ivig. He began vomiting approx 65 hours after his first does of the new antibiotic.

 

My son has myco P - this much we know. MycoP will cause a herx, just like lyme die-off, from everything I've read in researching chronic mycoplasma.

 

Dr K said that 10-20% of kids get this vomiting a couple days after ivig. I'm now thinking that that vomiting was a herx from the ivig... Maybe Dr. K's 10-20% have a type of infection who's die-off results in herx. The ivig was killing off mycoP (but not all the way!)..

 

Anyone else out there have the post-ivig vomiting, and vomiting with antibiotics switch?

[amyjoy]

hi norcalmom

 

funny it did not occur to me that post ivig nausea and vomiting could be a herx, i thought it was from the med itself, or maybe all that protein in the blood stream or i don't know exactly...but it didn't occur to me it could be a herx reaction.

 

my son did have a day of wicked vomiting after ivig, and so did a couple of other kids who had ivig in our practice, and i tell people that its common enough after ivig to just expect it and be surprised / happy if it doesn't happen. 20% sounds like a good number from our experience, post ivig.

 

vomiting after the antibiotics switch, that isn't something i have seen much in our practice or at all with my son, so i can't be helpful there. it just makes me wonder if its a sign your child isn't tolerating the current antibiotic but i'm sure someone on the forum will have words of wisdom for you.

 

good luck with it.

[philamom]

My dd had 4 HD IVIG. The first two she vomited. The second two she was given a very small dose of steroids halway thru the infusion...no vomiting. It also helps to be well hydrated (with oral liquids & bag of fluid during infusion) and to have the infusion administered at a slow rate. Even with all the above, they still may vomit.

[Phasmid]

my son vomited once or twice, even had a low fever for a short time. doc said it was common, not to worry. started day 2, ended on day 3 following IVIG

[norcalmom]

Phas -

your son had mycoplasma right?

 

I have read that kids who react less and less to it..could be that there is less mycoP(or whatever) to die off in the first place.

 

Anyone out there with known Lyme that had ivig and had ( or didn't have) vomiting?

[JAG10]

Hi Norcalmom,

 

My dd had her 2nd IVIG last week on Wed & Thurs, vomited Friday: one and done. I forgot to give her the friday dose of prednisone Dr. B prescribes for the 2 days pre, during and post ivig. When dh called me to tell me about the headache and vomiting, I realized I forgot, he gave it to her and she's been fine since.

 

With 1st IVIG, superduper headache after 2nd day dose of Ig, prednisone that night, then fine. 3 weeks later, mild fever, vomiting; 1 time, then fine. 4 weeks after that, same thing; mild fever, single vomiting episode, then fine. 5 weeks after that, same thing, mild fever, one vomit, fine: like outside running around, playing field hockey, fine. Those 3 single episodes @ 3,4 & 5 were it and they were very, very brief and ended at 12 weeks post IVIG.

 

My dd11 also had high myco-p; 1.65 before IVIG and over 3.02 nine weeks post IVIG, then back down again to 2.2 two months later. I am fairly certain she did not have exposure to myco-p between pre-ivig and post ivig measurements and she was on full strength abx the whole time. The measurement went up from the IVIG itself, but her symptoms-some very mildly worsened, but most of her symptoms significantly improved.

 

Jill

Edited February 13, 2011 by JAG10