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Posted

My daughter takes augmentin ES liquid form 600 mg/twice daily. When it is reconstituted, it is said to have a shelf life of 10 days. I have noticed the same cyclic pattern in my daughter for months now, that her PANDAS symptoms return or increase at about day 7 of that bottle of meds & then subside again when I start a newly mixed bottle (usually 2-3 doses into it). Anyone else noticed this? The pharmacist told me that the manufacturer guarantees that at 10 days the medication is as effective as day 1, but really who could test that other than them.

 

I'd love to hear from anyone that has had this problem with any liquid form ABX.

 

Thanks, Amy

Posted (edited)

Hi Amy

VERY acute and astute observation indeed. I did infact notice this this last time I had to up the dosage. When the 1st bottle was nearing the end I think, his tics ramped up and subsided with the new bottle. I will keep an eye on this. I refrigerate mine as do you I'm sure but still seems to be wearing off. I wish DS would take pills already but he just can't poor little guy.

Edited by sptcmom
Posted

We were in Cape Cod this past week and had to refill the rx's there-anyhow I talked with that pharmacist about my concerns and she broke up the prescription into 4 bottles, so about 7-8 days each to see if it makes a difference. Finally, a pharmacist that didn't think I was crazy (well maybe she did-I went crazy b/c at 9pm I arrived at the pharmacy to be told that insurance would not pay for two more days-well my girls were out of meds, I was on vacation & already had a ramping up in symptoms due to being at the end of the "shelf life") After they saw that I refused to leave without ABX and many, many calls to my insurance co & the CVS here at home, they corrected the mistake in their computer! (again, they must have thought I was crazy, they acted as though I was trying to refill a narcotic 2 days early) What we PANDAS parents won't do for ABX!

Posted

that made me smile:) I feel like bit of a abx junkie myself- starting our 3 abx since april, I feel wierd every time I go back, like they must be thinking, what the heck is wrong with kid :)

Posted (edited)

My daughter takes augmentin ES liquid form 600 mg/twice daily. When it is reconstituted, it is said to have a shelf life of 10 days. I have noticed the same cyclic pattern in my daughter for months now, that her PANDAS symptoms return or increase at about day 7 of that bottle of meds & then subside again when I start a newly mixed bottle (usually 2-3 doses into it). Anyone else noticed this? The pharmacist told me that the manufacturer guarantees that at 10 days the medication is as effective as day 1, but really who could test that other than them.

 

I'd love to hear from anyone that has had this problem with any liquid form ABX.

 

Thanks, Amy

Edited by cab40
Posted

Chris,

I go to the pharmacy the day I run out, since it's only good for 10 days. Now, this time around, with only 7 days between bottle, my daughter is doing well, quite consistent (I'm going on my Mom's report, as she's staying with them for the week). My parents have a lot to compare it to though b/c they saw firsthand last week what its like day 7-10 & then 1-2 more days until the new bottle "kicked in" I plan to get all future rx's in smaller parts, so we go no longer than 7 days at a time once it's reconstituted.

 

I'd love to hear how it goes for your child.

 

Amy

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