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Posted (edited)

To me, more interesting is the concept of streptococcal superantigen then the absence of D8/17 is a monoclonal antibody.

 

http://neuro.psychiatryonline.org/cgi/content/full/16/3/252

 

 

Superantigen:, one of a family of related substances, including staphylococcal and streptococcal exotoxins, that can short-circuit the normal sequence of events leading to activation of helper T cells. Superantigens initiate an uncontrolled proliferation of T cells but do not require processing and presentation by macrophages. The result is either an acute and potentially life-threatening disease, such as toxic shock syndrome, or a chronic inflammatory process, such as rheumatic fever.

 

ALSO: http://en.wikipedia.org/wiki/Superantigen

 

 

 

-Wendy

Edited by SF Mom
Posted

thanks wendy...i will add this to my print out folder!!!

 

To me, more interesting is the concept of streptococcal superantigen then the absence of D8/17 is a monoclonal antibody.

 

http://neuro.psychiatryonline.org/cgi/content/full/16/3/252

 

 

Superantigen:, one of a family of related substances, including staphylococcal and streptococcal exotoxins, that can short-circuit the normal sequence of events leading to activation of helper T cells. Superantigens initiate an uncontrolled proliferation of T cells but do not require processing and presentation by macrophages. The result is either an acute and potentially life-threatening disease, such as toxic shock syndrome, or a chronic inflammatory process, such as rheumatic fever.

 

ALSO: http://en.wikipedia.org/wiki/Superantigen

 

 

 

-Wendy

Posted

It is a gold mine but what happened to all of these DOCTORS that wrote the article!!!!! Anyway..... the superantigen stuff makes for good reading. BY THE WAY, in all my correspondence with strep experts.... they absolutely support the notion of superantigens and intercellular strep. AND, you wonder why a simple course of antibiotics doesn't work for PANDAS children.

 

 

-Wendy

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