sf_mom Posted June 17, 2010 Report Posted June 17, 2010 (edited) To me, more interesting is the concept of streptococcal superantigen then the absence of D8/17 is a monoclonal antibody. http://neuro.psychiatryonline.org/cgi/content/full/16/3/252 Superantigen:, one of a family of related substances, including staphylococcal and streptococcal exotoxins, that can short-circuit the normal sequence of events leading to activation of helper T cells. Superantigens initiate an uncontrolled proliferation of T cells but do not require processing and presentation by macrophages. The result is either an acute and potentially life-threatening disease, such as toxic shock syndrome, or a chronic inflammatory process, such as rheumatic fever. ALSO: http://en.wikipedia.org/wiki/Superantigen -Wendy Edited June 17, 2010 by SF Mom
Fixit Posted June 17, 2010 Report Posted June 17, 2010 thanks wendy...i will add this to my print out folder!!! To me, more interesting is the concept of streptococcal superantigen then the absence of D8/17 is a monoclonal antibody. http://neuro.psychiatryonline.org/cgi/content/full/16/3/252 Superantigen:, one of a family of related substances, including staphylococcal and streptococcal exotoxins, that can short-circuit the normal sequence of events leading to activation of helper T cells. Superantigens initiate an uncontrolled proliferation of T cells but do not require processing and presentation by macrophages. The result is either an acute and potentially life-threatening disease, such as toxic shock syndrome, or a chronic inflammatory process, such as rheumatic fever. ALSO: http://en.wikipedia.org/wiki/Superantigen -Wendy
amy s Posted June 17, 2010 Report Posted June 17, 2010 Wendy- this article is a GOLD MINE! Thanks for posting it. I don't think I have seen this one before?
sf_mom Posted June 17, 2010 Author Report Posted June 17, 2010 It is a gold mine but what happened to all of these DOCTORS that wrote the article!!!!! Anyway..... the superantigen stuff makes for good reading. BY THE WAY, in all my correspondence with strep experts.... they absolutely support the notion of superantigens and intercellular strep. AND, you wonder why a simple course of antibiotics doesn't work for PANDAS children. -Wendy
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