Dosage Question

[swim]

I saw a comment on another post about a dosage of keflex being too low. I checked out dosage guidelines and was surpised to see the dosage levels for keflex seem much higher than what we are using. With recent increase in symptoms, we are pulling our hair out! Wonder if anyone has any experience or comments about dosage for keflex. Our son is 11 yrs and 60 pounds. He is on 1,000 mg a day (2 doses of 500 mg) as we try to improve symptoms again. Does this seem too low?

[fuelforall]

I saw a comment on another post about a dosage of keflex being too low. I checked out dosage guidelines and was surpised to see the dosage levels for keflex seem much higher than what we are using. With recent increase in symptoms, we are pulling our hair out! Wonder if anyone has any experience or comments about dosage for keflex. Our son is 11 yrs and 60 pounds. He is on 1,000 mg a day (2 doses of 500 mg) as we try to improve symptoms again. Does this seem too low?

 

 

No. Try another drug as soon as a doctor will let you.

Augmentin (XR) or zith. Standard operating procedure around here.

[thereishope]

Has a higher dosage of Keflex worked before in improving PANDAS symptoms?

 

There are a few kids on here who ending up having the most success on Keflex. I belive they did try abx like Zith first and it didn't help.

[swim]

Has a higher dosage of Keflex worked before in improving PANDAS symptoms?

 

There are a few kids on here who ending up having the most success on Keflex. I belive they did try abx like Zith first and it didn't help.

 

The highest dose he has ever been on is 1,000 mg/day (two doses of 500 mg). He has been on that dose since mid-Jan due to a flare up of symptoms. His long term dose has been 500mg/day. The 1,000 helped at first with this latest worsening of symptoms, but now we are seeing a backslide. I left a message for our doc this morning to see about increasing keflex or trying augmentin. We have never tried augmentin for PANDAS. Waiting to hear back.

[thereishope]

If you first saw an improvement and now he's backsliding, in my opinion, I'd probably switch. I've heard that before. The first month they see what they believe to be improvement then a worsening. Does anyone know why that seems to be a magic time for when an antibiotic may stop working (around a month)?

[swim]

Doctor is going to have us try 1,500 mg keflex (500 mg 3 times a day) to see if we can get improvement before trying to switch to another antibiotic. I looked up dosage info and it looks like he could be on 1,360 to 2,721 for a strong infection based on his weight (60 pounds). So, maybe we have just not been on a strong enough dose when he has exposure to illnesses. We'll see ...

[thereishope]

Please keep us updated! I hope the increase works.