Probiotics

[jewels]

I just looked through the website (I don't work for them etc) and saw this new product which looks interesting. It supports gut while on abx. I have to buy this companys products through an Allergy hospital, but I don't know if you could buy it over the counter.

 

ABx Support™ is a carefully researched blend of the non-pathogenic yeast Saccharomyces boulardii with Lactobacillus rhamnosus, Bifidobacterium bifidum, and Bifidobacterium breve, probiotic microorganisms documented to support the normal gastrointestinal flora during antibiotic therapy. S. boulardii has broad, versatile gastrointestinal effects. It stimulates numerous intestinal brush border enzymes to maintain normal digestive functions, secretes many factors including enzymes that may reduce dietary protein allergies following gastroenteritis and polyamines that stimulate brush border hydrolases, proteases, and transport carriers. It stimulates D-glucose and sodium absorption and produces short-chain fatty acids such as butyrate and acetate that nourish colon mucosa. S. boulardii enhances the numbers of healthful bifidobacteria in the colon while simultaneously suppressing populations of pathogenic clostridia. L. rhamnosus is a transient Lactobacillus that colonizes the small intestines when regularly consumed. It favorably enhances innate and acquired immunity. It decreases T cell proliferation, induces helper (CD4+) T cell hyporesponsiveness, increases phagocytic activity in peripheral blood white cells and killing activity in natural killer cells, and inhibits production of proinflammatory cytokines. L. rhamnosus significantly augments serum and mucosal secreted antibody responses. B. bifidum and B. breve are two species indigenous to the colon’s microflora. Bifidobacteria are highly beneficial for normal bowel function and are exquisitely sensitive to most antibiotics. Consumption of B. bifidum and B. breve replenishes colonic bifidobacterial populations suppressing overgrowth by pathogenic microbes such as Clostridium difficile and Candida albicans. B. bifidum is among the many Bifidobacterium species normally found in large numbers in a healthy colon microflora. B. bifidum activates B cells making them more responsive to transforming growth factor-1 and interleukin-5 for IgA secretion. B. bifidum enhances IgA response to C. difficile toxin A. Supplementation with B. bifidum enhances white cell phagocytic activity. B. breve increases the immune response of Peyer’s patch cells stimulating B cell proliferation and antibody production. Clinical studies of the probiotic species in ABx Support™ have shown these microorganisms support against antibiotic-associated diarrhea, C. difficile bowel disorders, and rotavirus diarrhea.

 

This hypoallergenic formulation is provided in vegetarian capsules in bottles of 28 capsules, a convenient 14-day supply for concurrent use during antibiotic therapy.

 

Suggested Use: As a dietary supplement take 1 capsule twice daily with meals or as directed by a physician.

[smartyjones]

It might take a year to correct gut flora but we are willing to be patient and fix the flora. Once its repaired, all probiotics are stopped.

 

-Wendy

 

so wendy - how will you know when the gut flora is repaired? so you naturopath does not recommend for all general people to take a probiotic everyday for general health? just trying to understand.

i was trying to figure out that product you referred the page to - how many servings is a bottle?

thanks.

[sf_mom]

When their stool becomes loose and can no longer tolerate probiotic and they have normalized PH balances. Servings per bottle depend on how many units you are able to take per day. For example: 1 gram is approximately 300 billion units which is approximately one 1/4 teaspoon or about one adult size spoonful provided with product. One large bottle would be enough for 100 days @ 300 billion units per day.

 

Hopefully that helps.

[nevergiveup]

Wendy, I heard the exact same thing from my t and b cell expert. He studies autoimmune disease and immune defs, he said probiotics. What strains are you taking? Also did he run any b cell tests on your kids? They put my dd in a study to analyze how her bone marrow makes b cells and to see if anywhere along the b cell "maturation" process her b cells are being made wrong. Also analyzed t cells. Are you familiar with any of this science? I was suppose to get results last week, but apparantly the doc wants to go through each number with us personally. Yuk. Again what strains did the doc recommend the most?

 

Thanks,

 

 

I had not invested much into the probiotic aspect until most recently...... But, after speaking with a immunologist at Stanford Children's Hospital who is studying T and B Cells with regard to auto-immune, he commented there is some research being done through Stanford that is looking very promising with regards to probiotics/auto-immune. He also said some day, specific strains might even be recommended for certain types of illnesses/disease. The nutritionist we are consulting suffered from an auto-immune disease for 10 years and has been perfectly healthy for 16 years. Our son is on a very high dose, so I am glad we have her guidance, as well as testing PH balances to determine progress. We think its helping but we've also been very aggressive with our other treatment strategies and will be updating as we move forward.

 

-Wendy

[sf_mom]

Oooops see response below

 

It might take a year to correct gut flora but we are willing to be patient and fix the flora. Once its repaired, all probiotics are stopped.

 

-Wendy

 

so wendy - how will you know when the gut flora is repaired? so you naturopath does not recommend for all general people to take a probiotic everyday for general health? just trying to understand.

i was trying to figure out that product you referred the page to - how many servings is a bottle?

thanks.

[kim]

SFmom (& all),

 

I spent a little time on the website that you sent me (nutrionist) and thought you might like to read some of the info contained in this series too. Lots on role of probiotics/flora

 

Evidence based Complementary and Alternative Medicine (luv that)

 

 

excerpt from part two

 

In the previous article, we established the differentiation of activated T-helper cells into T-helper-17 (Th17) and the pathogenic role of interleukin-17 (IL-17) in neuroimmune disorders. Here we review the inflammatory pathophysiology of intestinal barrier permeability, which can lead to the breach of the blood–brain barrier (BBB). The tight junctions of the intestinal barrier may open due to environmental stressors, which can upset the microflora homeostasis thereby producing endotoxins that activate proinflammatory cytokine IL-1β. The upregulation of IL-1β begins a cascade of the inflammatory response system, resulting in high levels of IL-17-producing cells in various tissues. Additionally, the stressors that are capable of opening the epithelial tight junction barrier are also able to breakdown the BBB

 

 

 

 

http://ecam.oxfordjournals.org/cgi/content/full/nep062v1

The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part I

 

 

http://ecam.oxfordjournals.org/cgi/content/full/nep063v1

The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part II

 

 

http://ecam.oxfordjournals.org/cgi/content/full/nep064v1

The Role of Th17 in Neuroimmune Disorders: A Target for CAM Therapy. Part III

[smartyjones]

Also did he run any b cell tests on your kids? They put my dd in a study to analyze how her bone marrow makes b cells and to see if anywhere along the b cell "maturation" process her b cells are being made wrong. Also analyzed t cells. Are you familiar with any of this science? I was suppose to get results last week, but apparantly the doc wants to go through each number with us personally.

 

 

nevergiveup -- please do keep us informed about this -- sounds very interesting!

 

i thought the issue was more that the regulatory t cells do not do their job of stopping the immune response? so confusing and i admit i'm over my head in trying to understand.

[sf_mom]

Kim,

 

You are great!!!!! I think you fully understand why I'm heading down this route. The other night when he was exposed to 'pink eye' I gave him a 1/2 cup of the Bentonite Clay and that is what helped subside the cough within hours 'I think'. It pulls out the toxins or 'absorbs' them and eliminates through the bowel.

 

-Wendy

 

 

 

SFmom (& all),

 

I spent a little time on the website that you sent me (nutrionist) and thought you might like to read some of the info contained in this series too. Lots on role of probiotics/flora

 

Evidence based Complementary and Alternative Medicine (luv that)

 

 

excerpt from part two

 

In the previous article, we established the differentiation of activated T-helper cells into T-helper-17 (Th17) and the pathogenic role of interleukin-17 (IL-17) in neuroimmune disorders. Here we review the inflammatory pathophysiology of intestinal barrier permeability, which can lead to the breach of the blood–brain barrier (BBB). The tight junctions of the intestinal barrier may open due to environmental stressors, which can upset the microflora homeostasis thereby producing endotoxins that activate proinflammatory cytokine IL-1β. The upregulation of IL-1β begins a cascade of the inflammatory response system, resulting in high levels of IL-17-producing cells in various tissues. Additionally, the stressors that are capable of opening the epithelial tight junction barrier are also able to breakdown the BBB

 

 

 

 

http://ecam.oxfordjournals.org/cgi/content/full/nep062v1

The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part I

 

 

http://ecam.oxfordjournals.org/cgi/content/full/nep063v1

The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part II

 

 

http://ecam.oxfordjournals.org/cgi/content/full/nep064v1

The Role of Th17 in Neuroimmune Disorders: A Target for CAM Therapy. Part III

[justinekno]

Anyone know the order of when to take the probiotic? I know they should be taken two hours after taking an antibiotic but how about when you are taking Nystatin too? Can Nystatin and the probiotic be taken at the same time?

 

As some of you may know, we are currently doing high dose probiotics under the guidance of a nutritionist and thought I'd post this very interesting article that was forwarded to me by a parent on this forum.

[peglem]

I'm not sure of what to make of Keggy's post, though. She seemed to imply that I have ulterior motives in having started the project in the first place (the bit where she says I'm not doing it for practicality).

Yes, unless you are using S. Boulardii as probiotic. Boulardii is a good yeast, and Nystatin will kill it.

[justinekno]

Thank you!

 

Yes, unless you are using S. Boulardii as probiotic. Boulardii is a good yeast, and Nystatin will kill it.