Immune Tests Are In - IgA ?

[kim]

Well, rereading what I quoted, I think I'm wrong. I don't think they're saying that it would not dectect antibodies, only that the antibody formation would be due to a different component. Either way, I don't think we have the info that is really needed, which is how long is it reasonable to expect to find antibodies after a full couse of vaccination?

[peglem]

I think the vaccine Peglem's daughter was given was a polysaccharide vaccine with no aluminum (please correct me if I'm wrong Peg). Sure'em not trying to discredit anyone's Dr. I'm sure they have good explanations for viewing the findings as they are, just trying to figure out if there is significance to the lack of evidence of immunity for Prevnar strains specifically.

 

Allie received the pneumovax. I know that I did a search on it before allowing her to receive it and it contained no aluminum.

[Buster]

** edited 8/8 **

 

I'm not sure yet what this test means.

 

I'm reading some doctors take a base line, then re-vacinate, and then check antibodies 3 weeks later. There are other web sites that indicate a 10 year antibody response to challenge.

 

If someone talks with an immunologist I'd sure appreciate an explanation.

 

I'm wondering if the difference is those that were born pre 2000 (i.e., were not likely vaccinated) and those post 2000 (who probably got 4 vaccinations).

 

In our case, our dd had a response on serotype 19, 6B (26) with weak 18C(56).

The rest (1, 3, 4, 7F(51), 8, 9, 12, 14, 23) were negative. I didn't see values for the other serotypes.

 

The items in () are alternate names for same serotype.

 

I found the following web sites with the pre/post vaccination values but it doesn't appear to test multi-year post vaccination:

http://cvi.asm.org/cgi/reprint/13/8/905.pdf

 

 

 

Regards,

 

Buster

 

 

We too had low PREVNAR reaction for 11 of the 14 seratypes. Our immunologist wasn't particularly concerned with this despite our pointing out that our dd had been vaccinated 4 times. I think this is sure an interesting coincidence and worth seeing if others have had similar results.

 

Regards,

 

Buster

 

Buster, out of curiosity, which did your dd "pass"?

 

My dd was not low on 23F and 19F and 5 was a 2.0.

 

Susan

[kim]

http://74.125.95.132/search?q=cache:UiPi9k...=clnk&gl=us

 

Pneumococcal 7-valent Conjugate Vaccine (Diphtheria CRM197Protein), Prevnar, is a sterile solution of saccharides of the capsular antigens of Streptococcus pneumoniae serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F individually conjugated to diphtheria CRM197protein. Each serotype is grown in soy peptone broth.

 

http://www.merck.com/product/usa/pi_circul...neumovax_pi.pdf

 

1 2 3 4 5 6B** 7F 8 9N 9V** 10A 11A 12F 14** 15B 17F 18C 19F** 19A** 20 22F 23F** 33F

 

 

You can see below that Pneumovax is only on the schedule for "certain high risk groups" to be given after the age of 2 where the last dose of Prev, would/should have been given around 12 to 15 months. looks like 1 dose with a follow up single revaccination 5 years later for persons / children with functional or anatomic asplenia or other immunocompromising condition after 5 years. That info is provided in 2nd link ....Recommended Immunization Schedule for Persons Aged 7 Through 18 Years—

 

Recommended Immunization Schedule for Persons Aged 0 Through 6 Years—

http://www.cispimmunize.org/IZSchedule_Childhood.pdf

 

 

Recommended Immunization Schedule for Persons Aged 7 Through 18 Years—

http://www.cispimmunize.org/IZSchedule_Adolescent.pdf

 

My youngest son who had full series of Prevnar has had pneumonnia twice. Trying to figure out how old he was. He also had a mystery illness (i think that was the phrase worried dad used) with a very low white count and fever edging 105.

 

BTW, for anyone that didn't catch my mistake on previous post , adults are not given the Pneumococcal vaccine anually (oops... have never been that familiar with adult vaccine schedule!)