Stress Call!

[CSP]

Faith,

 

Yes, I remember Carolyn and the NAC/ACV, but I think her son really had something wrong and needed the sulfer-containing amino acids. I'm not sure if it had something to do with his glutathione, and needed the NAC to help maintain the levels of glutathione, I really can't remember.

 

I really believe my son has a hard time with all the aminos re: the tics.

 

I felt since his vit. levels were so good and he had been on a clean diet for 2 years it was a great time to see how he would do without the supps. Again hinging my hopes on the VitE/selenium for antioxident support. Even tho he also should have the coQ10 the selenium should help his body produce coQ10.

 

God Bless Faith,

CP

[ilovedogs]

Faith,

I just called my naturopath today to tell them that ds has been getting headaches more frequently and he suggested the NAC. Now, I'm leary of having ds take it since you had such a bad reaction from it. How is your son doing now? Have the vocals died down at all?

 

Bonnie

[kim]

I know this is kind of technical, but thought you all might want to read it anyway. Read the reference articles. Look up the words that you don't understand. It's almost impossible to understand how this may be good or bad for your child, if you don't do the leg work. How this relates to my kids, might not apply to yours at all.

The first statement was something I was focused on.

 

http://www.generationrescue.org/binstock/0...ne-Cysteine.htm

 

 

"Interleukin (IL)-1b is a pro-inflammatory cytokine that functions as a critical regulator of host defense in response to infection and injury. However when present in excess, IL-1b is extremely toxic..." (8)

and

 

whereas the new Ashwood et al findings (5) call attention to IL-1β, which Iyer et al describe as a cytokine related to cysteine pathways (8). A goodly number of peer-reviewed studies suggest the therapeutic value of N-acetylcysteine (NAC; eg, 9-13), with adverse effects a possibility (13). A recent review calls attention to NAC efficacy in several neuropsychiatric disorders (14).

 

 

*Faith, don't miss Bonnie's post to you, right above mine

[faith]

bonnie, sorry, I did miss your post, but I do have an update now.

 

Good News It seems that the waxing has died down as of this past Saturday, a week after the NAC.

 

The vocals persisted frequent and louder than I think I'd ever seen them thru this past Friday (so a whole week after I gave that NAC). Now I did mention that I had been persuing NAET, and so I brought the capsules with me for testing on Saturday morning. he did test weak to it, so we went ahead and treated him for the NAC. If it was a reaction from that, than I had to see if it would alleviate it. Well, it seems it did! He was better and better for the rest of the day, even having quiet periods of time. By Sunday (Mother's Day) I was so grateful because I was seriously considering making an excuse and not seeing my family, it would have been too obvious. He still has a vocal, but I'd say its down by 80-90%, like he was in the days before, so the exacerbation does seems to be over, Praise God. I really now think that the NAC was responsible. Don't understand tho, because I did give this to him about 10 months ago without any trouble, but perhaps his body has changed with the NAET treatments we are doing and he is absorbing more of the supplements so this was too much too soon. I was still kind of neutral on NAET, but this may have given me the confidence to keep going. I cannot attribute any other positives thus far, but I will certainly let you all know. we do still have a ways to go.

 

So for those who want to try the NAC, I would just start slowly with small amounts and go from there. ME? i will never touch it again.

 

Faith

[kim]

Faith,

 

Are you still working on the B12/folic acid pathway? Wondering if there is still a glitch there?

 

Wanted to leave a couple of things for you to look over

 

 

http://www.whfoods.com/genpage.php?tname=n...ent&dbid=54

 

What are toxicity symptoms for cysteine?

 

Consumption of foods containing cysteine, or its precursor methionine, is not likely to cause toxicity symptoms. However, cysteine is a brain excitoxin that can cause damage to brain cells in susceptible individuals. Such individuals do not metabolize the amino acid correctly, and, as a result, may be at risk for certain neurodegenerative diseases, including multiple sclerosis, amylotrophic lateral sclerosis (Lou Gehrig's disease) and Alzheimer's disease.

 

 

What factors might contribute to a deficiency of cysteine?

 

The production of cysteine involves several nutrients. As a result, dietary deficiency of methionine, vitamin B6, vitamin B12, s-adenosyl methionine (SAMe) and folic acid may decrease the production of cysteine.

 

 

http://www.whfoods.com/genpage.php?tname=n...ent&dbid=54

 

 

Children 1-3 years: 163 mg of cysteine

Children 4-8 years: 238 mg of cysteine

Males 9-13 years: 425 mg of cysteine

Males 14-18 years: 650 mg of cysteine

 

(bolding mine)

http://www.sciencedirect.com/science?_ob=A...296d2173b885072

 

Oxidized sulfur-containing amino acids are recognized as agonists of excitatory amino acid receptors in the mammalian nervous system. Homologues of glutamic acid (homocysteine sulfinic acid and homocysteic acid) and aspartic acid (cysteine sulfinic acid and cysteic acid) have been shown to be agonistic to N-methyl-D-aspartate receptors in animal brain and have been demonstrated in brain tissue. Considerable evidence exists for the role of homocysteic acid and cysteine sulfinic acid as endogenous ligands for excitatory amino acid receptors. We report, for the first time, the quantitation of these compounds in normal human serum, by a newly developed gas chromatography-mass spectrometry method that employs stable isotope-dilution selected ion monitoring using internal standards prepared in our laboratory. We also report new methods of synthesis of stable isotope-labeled internal standards used in measuring cysteine sulfinic acid, cysteic acid, homocysteine sulfinic acid, and homocysteic acid.

 

http://www.thorne.com/media/methionine_homocysteine_8-1.pdf

 

The Methionine-Homocysteine Cycle and

Its Effects on Cognitive Diseases

[faith]

whoa Kim, ooh, that is food for thought. I have abandoned the B12 shots for some time now (at least a year or so) because I ultimately did not see anything from it one way or another. his tics did not ultimately change for the better, they came and went, just as they do now.

 

But interesting this is, are you suggesting the NAC caused some problem for him because of the glitch in his methylation pathyway (recalll the MTHFR, he seems to not convert B12 properly and as a result, I think homocystein builds up, which is not healthy in the long run). It does seem he is sensitive to amino acids, I recall taurine, carnitine, and tryptophan seemed to cause increase in tics when initiated, so I did not continue on those. (by increase I mean more than usual, not causing tics when there were none.).

 

What do you think?

 

just to give a little more update, as I said, that crazy spike seems to have calmed, yet I am seeing little bouts of exacerbations at certain times during the day, so its been hard for me to gauge. He was doing loud and frequent vocals yesterday afternoon during homework, and while doing computer games. I don't think that it was caused by these things, but just noting that he did spike in little bouts, and then he'd be quiet, such as in the morning at breakfast and while watching tv at night. don't know what to make of this. (note: I am still going thru NAET treatments weekly and he did have one on Tuesday evening, so some of this may or may not be related to those treatments).

 

Faith