panlym Posted May 9, 2012 Report Posted May 9, 2012 Hi, We just got back the C4a and C3a test results back. I need help interpreting them C4a - 5720 Ref range is 1 - 2830 HIGH C3a -- 419 Ref range is 1 -940 What do they mean? Is this test suggestive of Lyme? Mycoplasma IGg - 437 Ref Range 0-99 HIGH My DAN says the IGg is not high enough to suggest chronic Mycoplasma infection. But I have read otherwise. Anyone with higher numbers than these? Thanks.
sf_mom Posted May 9, 2012 Report Posted May 9, 2012 C4a is an inflammation marker. It generally correlates with symptom presentation C3a is an autoimmune marker C4a can be due to infection http://betterhealthguy.com/joomla/blog/216-ilads-2010-conference-takeaways
fightingmom Posted May 9, 2012 Report Posted May 9, 2012 WOW! I need to have that test done for my son. Your result is double the high end of normal range. That's a lot of inflammation, no?
LNN Posted May 9, 2012 Report Posted May 9, 2012 Here is a link to the research paper that explains what each marker might indicate regarding lyme and mold, written by Dr Shoemaker. It's been awhile since I read it, so I could have it wrong, but I seem to recall that high C3a was linked to lyme and high C4a could be either lyme or mold. But your best bet is to read the article and not rely on my poor memory. http://www.jacemedical.com/articles/C4a%20C3a%20testing%20for%20Lyme%20disease.pdf
JuliaFaith Posted May 9, 2012 Report Posted May 9, 2012 Just for comparison purposes, about 1 year ago my ds14 results were: C3a - 157 (per dr. indicative of lyme) C4a - 2632 (dr. said this was probably much higher before heavy detoxing began) (indicative of mold per dr.)
SSS Posted May 10, 2012 Report Posted May 10, 2012 My C4a was 19,000!! I really freaked. Kept waiting for my head to explode until my next LLMD appointment. I was told it was an indicator of chronic Lyme, possibly mold involved. To me, it is like the CD57 test- all pieces of the puzzle. Haven't had a C4a test again (that was 9 months ago) but have been treating Lyme and co. ever since, and we went through a long mold protocol. I also take 1,000 mg. a day of Longvida curcumin to help with inflammation. FWIW, my daughter's C4a was in the normal range.
SSS Posted May 10, 2012 Report Posted May 10, 2012 Sorry, I wanted to add something about the C4a testing: My test was sent to the Jewish Hospital (lab) where I got my 19,000 result. We did a blood draw for my dd's to be sent there, the Jewish hospital lab screwed up the blood specimen, was told we had to do another blood draw. Our LLMD's office at the time was far away (they did the draws there for the Jewish hospital lab) None of the local labs in my area, labcorp or Quest, would do the draw and send it there- I spoke to labcorp, they said they had changed their method on their C4a test, it would be the same as the others. So, had another blood draw on dd for labcorp C4a, it came back normal, LLMD did not believe it, but I refused to do a 3rd draw for this test (and pay for it.) Also, on inflammation, about 3 months ago found out I have a high intolerance to gluten (not Cealic) went 100% gluten free, believe this also really helped inflammation.
JuliaFaith Posted May 10, 2012 Report Posted May 10, 2012 We are also gluten free to keep inflammation down as much as possible. Our Dr. had Labcorp send C4a/C3a to Swedish labs the first time but now Labcorp does the testing.
panlym Posted May 11, 2012 Author Report Posted May 11, 2012 Hi All, Thank you all who have responded with your suggestions. I'll be doing the mold testing next and will post about it then. Thanks.
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