Positive myco AB (IGG), EIA

[1tiredmama]

I just received ds's bloodwork results by mail today. Everything is normal--ANA, tick-borne infections, CBC...--but he has a positive result for myco. Is this significant by itself?

 

Result:

 

M. pneumoniae AB (IGG), EIA 3.32 ( <= 1.10 is positive)

 

M. pneumoniae AB (IGM) is negative

 

Thank you!

[WorriedDADNMOM]

I am sure there are more knowledgeable people on here but our dd's mycoplasma Igm was 5.9 H. H meaning high----with 1.1 was positive. Ped did not even tell us. Found out on our own after pulling the records. My gut tells me that this would be normal in your case but I am not sure.

[coco]

Positive igg myco p could be of significance. Although igg is indicative of past exposure/infection, high myco p igg in some doctor's opinion is cause to treat. Dr T is the one who treated my dd after other docs dismissed at as ok. Dr T always said, "there's something about high igg myco p.". He treats with biaxin and my dd did improve. You may want to treat and retest to see if it's on the way down. My dds was +5.00> and dropped to +3.50> after a long course of abx. It took it many months to drop. We just retested and are awaiting results. Good luck.

[nicklemama]

I have/had high mycoP IgG. I am being treated for it w/ minocycline. I've been on minocycline for 7 months. My last blood draw the IgG titers dropped to equivocal. I have rheumatoid arthritis believed to have been caused by chronic mycoplasma infection. My IgM titers are negative.

[1tiredmama]

Thank you for your replies. I don't know much about how autoimmunity works. I was wondering if his positive is high enough to cause an autoimmune reaction (and, thinking probably not.) However, ds was taking doxycycline for acne from August until just a few weeks before his blood draw. Perhaps, his low positive was, at one point, higher.

[norcalmom]

As stated above - IgG positive means you had it. But - that looks to be 3x the range, so significantly high. You need to take the test again in a few weeks to see if the number is going up or down. Its the only way to tell.

 

Doxy is good antibiotic for it, but need so be a fairly high does. I think the acne dose is much lower, and in that case you might want to consider something other than the Doxy - since it has been exposed to low levels of it could be developing resistance to it.

 

How high the number isn't tooo significant -(your question about high enough to cause an autoimmune reaction) - positive is positive. IT will keep climbing higher and higher if the immune system is trying to fight it unsucessfully - so the number also how long you are infected.

[1tiredmama]

Thank you, norcalmom! A few questions:

 

1. Ds was taking 100mg of Doxy twice a day. Is that low for myco?

 

2. How long should I wait to retest?

 

I REALLY appreciate your help!

[norcalmom]

my DS is going to be 13, and is about 125 lbs. He is on 300mg/day (150 morn/150 night). this for Doryx (not Doxy..should correlate but not 100% sure). Its high. Not everyone can tolerate that, but that is the does recommended for adults with chronic mycoP. He will take a break for a couple weeks soon.

 

I don't know about the retest yet - I asked at my last appointment (we had been on the Doryx for about 2 months and they said not yet) but we were trying to see if it was going down - not up. I'd assume it goes down slower since I know it can stay high for a long time (meaning you had an infection - it may not correlate). But going up is a different story. You could email Dr Garth Nicholson. He may know. He is the microbiologist that discovered that gulf war syndrome was really mycoplasma pneumonia.

 

Try the email on this page: http://www.immed.org/reachus.htm

 

 

He has some, sort of consipiracy theory videos on the web - don't be put off by them. He knows his mycoplasma. He just doesn't trust that the army (ours or theirs) (he was actually in the Army I think - I know his daughter was). Anyhow, he has some interesting stats on people that had vaccines before going over there and the number of them that came down with mycoplasma (very high - they were give 20 so vaccines in a week or two) versus those that for wahtever reason didn't get thier vaccines...as well as those with active mycoplasma that had kids with autism. Very high percentage.

 

Good luck -send him an email with your questions, and look at the documents on his site for lots more info.

[butterflymom]

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Edited October 5, 2015 by tampicc

[1tiredmama]

Norcalmom, thank you for your reply. I will look into that link.

 

Tampicc, I don't have much to offer as my ds has not been dx'd yet. We just got his rheumy to run some bloodwork while waiting for a PANS eval in May. I can tell you this, he tics--A LOT--at its worst years ago, 1000 tics an hour! He has every PANS symptom, except OCD.

 

I hope that you get the Myco infection cleared and that your ds's tic subside.

[tpotter]

Norcalmom, thank you for your reply. I will look into that link.

 

Tampicc, I don't have much to offer as my ds has not been dx'd yet. We just got his rheumy to run some bloodwork while waiting for a PANS eval in May. I can tell you this, he tics--A LOT--at its worst years ago, 1000 tics an hour! He has every PANS symptom, except OCD.

 

I hope that you get the Myco infection cleared and that your ds's tic subside.

 

 

1) You should check everyone in your house to see if they have mycoP. Turns out I was the guilty party, and am still trying to treat it after 1 1/2 years (it's mostly under control, but still flares.) When my mycoP IgM flares, DS16's IgG goes up, too...last time went from 3.2 to >5. I asked my lung specialist about the significance, and even he said that it was more than likely very significant (he's rather conservative, and would normally have said not to worry about high IgG). He said to test my DS's sputum.

 

2) Garth Nicholson, who is recognized as THE specialist in treating mycoP talks about using doxy and azithromycin OR biaxin. I'm allergic to biaxin, so I use doxy and azith. It's a long haul to treat it completely, and I would recommend that you check his blood every few months to see if the numbers are going down. Another person has recommended that we try berberine (she read somewhere that it helps.) Anyway, we tried it on DS16, and he herxed so badly that he's now afraid to try even small amounts.

 

3) I know you said that his lyme was normal, but keep in mind that blood tests (except the new one) have a lot of false negatives, so that even if it comes back negative, the person may be positive. This is why lyme is recognized as a clinical diagnosis. If you are dealing with mycoP (which you are, even with high IgG only), it sounds like lyme/co-infections may very well be an issue, because mycoP can be a co-infection of LD. I would suggest you find a good llmd in your area, because they are also the ones who will treat long term with abx cocktails.

 

 

MycoP is a very tough, very resistent infection to treat, and causes a lot of damage. My lung specialist found that I have permanent damage from the treatment (I was sick for about 3 years before I was diagnosed with it...I had all the symptoms, that's how I know it was going on all that time.)