Lab Results - any thoughts?

[mdmom]

We have known for 1.5 yrs. that my DS14 has an immune issue, as he was dx with PANDAS and then Lyme, Babesia, Bartonella. But 1 yr. ago his IGG levels weren't "out of range," although they were still low-normal.

 

Now they are low out of range. Can Lyme treatment (we're 8 mos. in) suppress immune system even more and cause a Primary Immune Deficiency?

 

Here are his results:

 

IGG, Serum 757mg/dl (range 842-2013)

 

IGG1 491mg/dl (range 315-855)

IGG2 130 mg/dl (range 64-495)

IGG3* 18 mg/dl (range 23-198)

IGG4 47.3 mg/dl (range 11.0 - 157.0)

 

IGG TOTAL 803 mg/dl (range 842-2013)

 

Also, each month his neutrophils are low - this month they were 1330 (range 1800-8000)

 

White Blood Cell count is always low (probably b/c of Babesia) - 3.1 this month

 

Any thoughts?

 

Even a little sniffle tips the scales for him and he gets more ASD symptoms, OCD and anxiety. You all know the story too well.

[MichaelTampa]

I have heard abx suppress immune system and I would think fighting the lyme is going to cause a big fight and use up a lot of the immune system antibodies and whatnot, so seeing lowered counts there following initiation of treatment does not seem that strange to me (not a doc, never been told that by a doc, but just my thoughts).

[LNN]

I don't have any insights on the IgG levels. But have you tested plasma zinc levels and for KPU? I have been totally amazed at how much healthier we all are since starting KPU treatment for the kids and me. My son's IgG levels were always poor side of normal, but he caught every cold and shared it with DD and me. The only one who never got sick was my husband. Since adding zinc for KPU, 180 turnaround.

 

metals might also suppress the immune system. Just thinking out loud. No expert on PID by any means.