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Posted

I'm going to google it now, but I wanted to ask my pandas family what this means? Dr. B ordered tests for our whole family....besides the pandas dd.

Mycoplasma pneumoniae is supposed to be <100

Dad's results are 270

daughter (age 6) was 823

Obviously this is a reason why pandas dd7 can't get well, but what does this mean for the family members that have these results?? Any advice would be great....we don't get back up to see him again until April 4th. thanks pandas family!!

Posted

HI Kbossman-

Is this for IgG or IgM? IgM indicates current infection. IgG indicates past infection - your IgG can stay elevated for a long time. 823 isn't as high as it looks. my son's is 2450. And you can find case studies of kids with 32,000 and 80,000 on line.

 

It could be an indication of chronic infection but you can't know that unless you can confirm it with a PCR test...OR you can keep testing the IgG titer and see if it is going up, or down (just like strep titers). There just aren't any good studies on how long these titers stay elevated. But if it is going up - that's a an indication there is still infection. The theory is that very high titer indicate that your body keeps pumping out more an more antibodies (IgG) because the infection is still there.

 

BUT eventually, it may stop doing this. So, you can have NO titers and have chronic mycoplasma as well.

 

There is evidence that the IgM does not go up in subsequent infections in many people. So, absence of IgM means nothing. High IgM confirms you have active infection. Rising IgG indicates infection. Stable or falling IgG indicates your body was exposed to mycoP, and developed antibodies to it (the way it is suppossed to).

 

PCR is another way to test - it looks for the actual mycoplasma bacteria, not the antibody to it. Only speciality labs do this testing.

 

Hope that helps. PM if you want more info on treatment of chronic mycoP.

Posted

HI Kbossman-

Is this for IgG or IgM? IgM indicates current infection. IgG indicates past infection - your IgG can stay elevated for a long time. 823 isn't as high as it looks. my son's is 2450. And you can find case studies of kids with 32,000 and 80,000 on line.

 

It could be an indication of chronic infection but you can't know that unless you can confirm it with a PCR test...OR you can keep testing the IgG titer and see if it is going up, or down (just like strep titers). There just aren't any good studies on how long these titers stay elevated. But if it is going up - that's a an indication there is still infection. The theory is that very high titer indicate that your body keeps pumping out more an more antibodies (IgG) because the infection is still there.

 

BUT eventually, it may stop doing this. So, you can have NO titers and have chronic mycoplasma as well.

 

There is evidence that the IgM does not go up in subsequent infections in many people. So, absence of IgM means nothing. High IgM confirms you have active infection. Rising IgG indicates infection. Stable or falling IgG indicates your body was exposed to mycoP, and developed antibodies to it (the way it is suppossed to).

 

PCR is another way to test - it looks for the actual mycoplasma bacteria, not the antibody to it. Only speciality labs do this testing.

 

Hope that helps. PM if you want more info on treatment of chronic mycoP.

Hi.. My son has mycoplasma that he can't seem to get rid of. I am curious about this pcr testing... Does finding the actual mycoplasma instead of the titer, help in getting rid of the stubborn infection?

Thanks!

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