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Hi all.

 

Just got DS9's urine DOT BLOT test back today. Sent in two samples -- one taken on day 21 (last day) of 500 mg azith and one taken two days after that. Not the normal provocation protocol, but he was on the azith for something else and that's what we were able to do. The first sample came back positve and the second one was negative.

 

My understanding is that a single postive DOT BLOT is a smoking gun for Lyme. Is that true? Igenex's lab results say that it is a presumptive postive diagnosis, since there can be cross reactivity. They test for antigen reaction to these BB antibodies: 23-25 kDa, 31 kDa, 34 kDa, 39 kDa, and 93 kDa.

 

I am seeking any thoughts, encouragement or cautions. My son has pretty much switched from constant tics (3 years of duration) to triggered compulsions (about one or two months in duration).

 

Thanks.

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Yes-all you need is one positive to have Lyme. That's what my llmds said. A dot blot positive means that they found dead Lyme not just antibodies so it is definite. It is not easy to find in urine so a negative does not mean there is no Lyme. Good luck -it is treatable so now you know what to do.

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Thanks. When I got the results I was so happy and emotional -- I began to cry. Then, I started thinking about that "presumed positive" and there is info out there that you should confirm the DOT BLOT with a "reverse western blot" on the urine but we didn't order that and I have to call Igenex today to see if it is too late (I'm sure it is, it took forever to get the results back due to administrative and communication problems) and that just got me wondering...even more tests????.

 

Yes-all you need is one positive to have Lyme. That's what my llmds said. A dot blot positive means that they found dead Lyme not just antibodies so it is definite. It is not easy to find in urine so a negative does not mean there is no Lyme. Good luck -it is treatable so now you know what to do.

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