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Hi, folks, We saw a lot of OCD relief when my ds14 went on ibuprofen. Many others report the same. We are beginning to try pterostilbene supplements. There are a few companies out there who have them. VERY powerful bioavailable natural anti=inflammatory. I don't use this company with the link below, full disclosure. But this is a nice summary. http://www.pteropure.com/ptero/index.html I would also call attention to the work of Harvard's David Sinclair and NAD as possibly helpful. Much of the work on the cells that age and reducing this aging process can have applications in our own lives, and our children's. Reverse the aging process, reverse aging of the brain that comes with our children's condition. https://www.yahoo.com/health/researcher-hunting-the-key-to-aging-believes-95193101362.html We will let you know how this goes. Celebrex, with all its side effects, has had some good success with a couple of people's children here. Why not a more natural more powerful version?