DS16 had first flare at age 10 with coxsackie and strep. Sudden/severe onset OCD, behavior changes, anxiety, new onset bedwetting, extreme separation anxiety (school refusal) and all the rest. Treated with 10 days of penicillan. Pediatrician suspected PANDAS and advised this was the only treatment available at that time (2008) In retrospect, there were less severe flares at younger ages with impetigo, sinus infections, etc. One flare included tics which resolved and never returned. Several less severe flares between ages 10-13. Most severe flare to date with myco p and strep at age 14 with sudden onset OCD/Anorexia, anxiety, new onset bedwetting, hospitalized for 2 weeks and now in remission. His treatment so far has been a regular course of antibiotics from pediatrician when an infection has been diagnosed and 4 months of Clarithromycin a year ago for myco p. Currently not on antibiotic. We have an appointment to see Dr. F and Margo T. @ Stanford next week. We are living in fear of another flare due to the fact that the last one was life threatening. What treatments should we consider? Also, positive Lyme test (Advanced Lab) I'm hoping some of you who have received more treatment will weigh in on what we should be looking for treatment wise. DS has returned to close to baseline with each previous flare, but this last flare not so much. There is a much higher level of ocd remaining. This is a high school junior looking toward college. Another flare of that magnitude will alter the course of his life. Thank you for this forum and any advice you can give.
