orthomolecular

I HAD low stomach acid because of my deficiencies. But because of the supplements I take now, like nicotinic acid and pyrdixine HCL, I don't use those supplements anymore. I stopped taking the HCL supplements shortly after I started supplmenting for pyroluria. I was having problems with too much acid a while back. I was burping after meals, feeling this pressure build up if I ate a heavy (high fat and protein) meal and ocassionaly acid reflux. But the bi-carb, I think, really helped with that, especially the burping and the pressure build up after heavy meals. If the deficiencies are being treated than I don't think low acid may be the problem. One thing that is overlooked is the pancreas producing bi-carbonate. Without enough bi-carbonate by the pancreas the enzymes produced by his pancreas will not work. (Plant based enzymes are not supposed to need the precise ph to work, but animal derived enzymes do need the right ph level.) In Brain Allergies, Philpott and Kalita talk about using enzymes and bi-carbonate for those with pyroluria (or a severe b6 and zinc deficiency). I had a problem with the prydixine not working for me a while back. This problem was corrected by enzymes. I think that the synthetic form of b6 does not get converted if your pancreas is not producing the enzymes it is supposed to. (Or, if the pancrease doesn't produce bi-carb then the enzymes produced may not work because of the wrong ph in the GI tract.) I sometimes use the Source Natrol's Coenzymated B6, which is the P-5-P form in sublingual tablet. This product is called "coenzymated" which I think helps to make the case that the synthetic form will only be converted with the right enzymes. I think if pyridoxine is not working and it seems like he needs more p-5-p then his body is not able to convert the synthetic form into the active form. Enzymes will correct this problem, but you do need to use some bi-carbonate. I use Alka-Aid (tablets) by Vitaline Formulas. (The only other bi-carb I know about is Alka-Selxer but that contains aspirin too for some reason I don't understand.) I used those betaine HCL supplements for several years and think they are a big waste of money. They can't put any kind of acid into a capsule because the acid would destroy the gelatin capsule. They make the acid pretty inert (by adding the betaine), so I would take as many as 25 of the high potency capsules for my lunch. Those supplements are not that effective. I think vinegar might be better than those supplements, if you think low acid is the problem. I was spending around $75 a month on that stuff before I corrected my deficiencies. I am so glad I don't have to waste my money on those betaine HCL supplements anymore. Even after using 25 capsules for my lunch I still would not get that warm sensation in my stomach, which indicates that they are working. I think enzymes would be a better idea than those betaine HCl supplements. And do not forget the importance of a bi-carbonate too. But anyone with pyroluria, or other severe deficiencies of nutrients that play a role in digestion may need to supplement HCL. Yes, this is possible but if those deficiencies are being treated then I doubt the HCL is needed. The synthetic form of b6 will produce stomach acid, but this is not the only nutrient involved. Nicotinic acid on an empty stomach will increase acid levels. Nicotinic acid supplements can have the same effect as being injected with histamine in your muscle. This injectinon is how they trigger acid production in the stomach to do the Hiedleburg Capsule test. There are tests like the Hiedleburg Capsule or putting something down the throat to scoop out some stomach contents but I have never had those tests. The Hiedleburg is not equipment most doctors have. But I think that if eating protein especially is a problem then enzymes with bi-carbonate would be a better way to go (if you supplementing the needed nutrients too). And if the b6 doesn't seem to be working then I think enzymes may help that too. But instead of trying to figure out how much of those HCL capsules may be needed you might consider using some vinegar instead (temporarily), because it may be needed for only a short time if the deficiencies are being corrected. I think if the synthetic form of b6 is not working (or more p-5-p is needed) then this can be a sign that enzymes are needed.

You might consider buying some Zinc Status. It is possible that the dose you are taking is not doing enough. Zinc Status costs under $20 and will tell you immediately if you have a zinc deficiency. Consulting with a doctor will not tell you conclusively if you have a zinc deficiency. Very few doctors actually use this product, Zinc Status, in their practice. But you should be under medical supervision when it comes to treating a zinc deficiency. Giving yourself a copper deficiency is a real risk when taking more than 60 mg. of zinc per day. Have you tried some melatonin? I have read that the body needs zinc to make melatonin. Instead taking zinc and possibly causing an imbalance of zinc and copper you might try some melatonin.

I don't think an allergy to b vitamins is possible. Some types can have a reaction to some b vitamins, niacin (nicotinic acid) and folic acid mainly, which raises histamine levels. Histamine is responsible for allergic reactions and some people have too much histamine in their bloodstream. So, taking either nicotinic acid or folic acid is not recommended and the nicotinic acid especially will cause the flushing which some people may think is an allergic reaction. That flushing is normal but not something that a high histamine type wants to experience. But the niacin flush is not an allergic reaction although it may feel like one. It may be possible that your naturapath does not understand about histamine levels and how the right nutritional supplements can be used to balance histamine levels in the body. This approach of balancing histmaine levels using nutrition is used by orthomolecular trained specialists. http://www.diagnose-me.com/glossary/G610.html And as to the supplements if they may have helped.... If you are a high histamine type than those supplements could have a very positive effect. Calcium and magnesium are needed by histadelics (high histamine types) to help lower histamine. So those supplements should not be ruled out as being helpful to you and possibly causing this improvement. (You might want to test this again with just the supplements.) Nutritional supplements can help to balance your histamine levels, but your naturopath may not know how to do this. You may want to try researching this yourself if your naturopath is unfamiliar with this concept. I think the Naet treatment worked only the second time for mold because the supplements lowered your histamine levels. It may be possible that the combo of the two, Naet treatment and nutritional supplements might do the trick better than just the supplements. But those supplements can improve your allergic reactions because ther lower your histamine levels in your bloodstream. Besides calcium and magnesium, vitamin c is also supposed to help lower histamine levels. (And high histamine types also need zinc but I don't think it effects histamine levels directly.) Amylase, a digestive enzyme for carbs, lowers histamine levels too. There are other supplements you should take but this is not something I just tell you. You need to research this and do this under medical supervision. If you do have high histamine levels, then you should take your b vitamins separately, avoiding folic acid altogether. You should supplement other forms of niacin but the flushing kind (nicotinic acid), niacinamide is probably the most cost effective form for you. And that means you would have to avoid taking a multi vitamin too.

According to orthomolecular high histamine types should avoid folic acid and nicotinic acid (the niacin form that causes the flushing). Folic acid may cause problems like feelings of spaciness or depression. That flush (from niacin) is simply the basophil and mast cells filling up with histamine. For some histadelics they may also need to avoid b12 which can also raise histamine levels; but this is not so clear cut as the other two nutrients. But there are specific nutrients known for lowering histamine levels. But high histamine types should supplement niacinamide. This form and the other one, insolital hexi-something, will not cause any problems for a histadelic. Amylase, a digestive enzyme for carbs, is also known for lowering histamine levels. When a doctor does a blood test it is possible to have whole histamine levels checked.

Tryptophan has a known toxicity. I don't believe that using 5htp is good advice. (Unless your doctor warned about the specific side effects of 5htp and made it clear that using 5htp requires supplementing b6 in pretty high doses. And also mentions that need for niacin too.) The people most likely to try 5htp may be those who have a possible b6 deficiency. Taking 5htp would only make their problem worse. And they may also need more niacin too. This is something that needs to be done under medical supervision. You should talk to your doctor about changing your supplements. But the vitamin b6 is so much more important than the 5htp is. And I would hope niacin levels are good too. I think that your child's b6 deficiency is being made worse by the 5htp. The body needs b6 to convert the tryptophan into serotonin. Like I said I don't use 5htp. I tried it and found that it caused me some of those symptoms listed on the site on my previous post, symptoms like trembling and shaking. Ask you doctor why they recommended it. I would be interested in that explanation. I don't understand why you are taking some amino acids (SAMe & 5htp) without any b vitamin supplements? That sounds like either bad advice or your child is due for a urine test in a day or two. Using those amino acids can cause problems if the proper b vitamins are not supplemented too. I have read that some doctors may do something like an "informal" tryptophan load test. Instead of the patient sitting in the office after consuming tyrptophan, which can be time consuming, they recommend the diet stay the same and supplement tryptophan (or 5htp) to see what metabolic waste products appear in the urine. If something like xanuthuric acid shows up then it indicates a faulty metabolism of tyrptophan into serotonin. But is your child due for a urine analysis anytime soon? I did have a problem with the synthetic form of b6. That form would cause me indigestion and even somtimes acid reflux. I had tried higher doses (than 50 mg.) of p-5-p but found something else that works better. I take digestive enzymes now. I find that since taking enzymes I don't have the GI issues I used with the high doses of b6 I was taking. (Of course there were signs that my body was not absorbing the b6 too.) I honestly think my body was not able to convert the synthetic form in the active form because of lack of enzymes. I only take 50 mg. of p-5-p with each meal. This is something you might consider. It is true that some people will have a problem at some point with the synthetic form of b6. I don't know why anyone would need higher doses (than 50 mg.) of p-5-p except that there is a problem with converting that nutritent into the active form. Do you think the higher doses of p-5-p are helping?

Toxicity, side effects, interactions, and contraindications Tryptophan may cause some people to become drowsy, dizzy, or less alert than they are normally. This medicine may cause dryness of the mouth. Symptoms of tryptophan overdose include agitation, confusion, diarrhea, fever, overactive reflexes, poor coordination, restlessness, shivering, sweating, alking or acting with excitement you cannot control, trembling or shaking, twitching, and vomiting. Avoid combining l-tryptophan with other serotonin increasing agents such as 5-HTP or SSRI drugs, such as Prozac, Paxil, etc. Source: http://www.vitamins-supplements.org/amino-.../tryptophan.php

I can sweat when I sleep and I think mine has to do with my b6 deficiency. If he is low in serotonin then I think b6 is more important than 5htp. I can't use 5htp because it makes my b6 deficiency worse. The body can NOT convert tryptophan into serotonin unless there is sufficient b6. I don't recommend that people who may have a b6 deficiency use 5htp. Being low in any amino acid may indicate some other problem like not breaking down proteins properly or possible a low protein diet. But if any doctor recommends 5htp you should question the logic behind that. Tryptophan has some toxicity in the brain if it is not converted into serrotonin. If the diet is sufficient in protein and digestion is not a problem, then there is no need, I think, to supplement 5htp (or tryptophan). But supplementing 5fhtp in some people can make them feel worse.

Actually some people don't realize that corn starch is used instead of talc in some powders. I would wonder if it might be corn syrup or corn oil contaminating the chicken or beef your child eats. Our food can come in contact with so many things additives, perservatives, flavorings, who knows. But products made from corn are more plentiful than products made from wheat or gluten, so a corn allergy can be a tricky one to deal with.

One thing I have read about is using a rotation type diet. (Some people call it rotation and some call it rotatary diet.) This is for food groups or really food families. You can not eat any food from each family for four days. That is if you have onions on Monday, then you have to wait to have some garlic after 4 days. This method means that you or your child can have some foods that may not be "fixed" allergies but more like floating sensitivities. The point is that there may be people who find that some food or some family of foods may not be allowed for them EVER. But there may be some foods that you can use on a rotation basis. So, for example, even though you have a problem with diary you may be able to have it every fourth day, but the gluten may be different and you just can't have it ever. A rotation diet is supposed to start with a fast for something like 4 days, I think. (I am not sure exactly how long the fast should last at the begining. There are many books that explain this process.) Then you have to avoid those foods you have a problem with three months at the most. Sometimes it may take only 3 weeks to do the elimination phase but sometimes to be safe three months is recommended. After this period then you do the rotation part. It is helpful to have some reference materials on food families, obviously. For other things, like additives, you may still consider this idea. Sometimes you can have a substance in your system in small amounts and may not feel so bad. But eating it everyday will build up levels in the body that can have an impact on your health. I have seen some exceptions. You can have a food before those 4 days are up if you eat that food by itself. Sometimes having one food at a meal can help, sometimes just having two foods at a meal can also work for some too. This is something you can figure out by trial and error. This is one suggestion of ways of experimenting with foods that cause problems. This has some advantages to avoiding those foods completely, because they say that eating the same foods over and over again may make you prone to becoming allergice to them or additive to them. Variety is good, if you can have manage the rotation schedule. Another thing I read is that if you get your b6, zinc and magnesium levels up then these foods may not have the same reaction. (This suggestion is from Brain Allergies by Philpott and Kalita, and I think those are the three nutrients recommended but I may be wrong.) Some doctors will try injections of these nutrients before testing those offending foods. And these supplements do seem to help with these reactions, most of the time. This book also recommends some heperin to reduce the inflammatory response from the offending food. Heperin is used in high doses to thin blood. I am not sure if heparin is still available in this form (lower doses). You may consider using some other types of digestive enzymes instead, perhaps bromelain. Of courese, if you or your children have any sensitivities or food allergies then you should be using digestive enzymes anyway. These can help you get the most nutrition out of what you are eating. I have pyroluria and have realized how these deficiencies (vitamin b6 and zinc) has effected my pancreas, and its production of bi-carbonate and enzymes; so, these deficiencies especially can impact on your digestive system. I use digestive enzymes with food and on an empty stomach too. It really is a trial and error process with most people and problems with foods. But you might consider waiting until you have some time of "being good" under your belt before you start experimenting with some "bad" foods. And, of course, having your nutritional status in good shape can help too.

Thanks for the clarification. This post here says 12 was considered borderline. http://www.latitudes.org/forums/index.php?...=648&hl=kp+test "I am starting to add zinc and b2, since he is borderline at 12, and may have him retested." When I was sick (I have had ulcers develop) I would stop my supplements for a couple of days. Things will level out for you, I think. I mean that you may at first notice the symptoms coming back (the first day) but things do get better and you hardly notice any symptoms once your body gets used to being without supplements. Honestly, if I stopped all of my supplements I probably wouldn't do that bad for a a short while because the body can adapt to this change. Now, if you anticipate any stress during this period then you should definitely That has been my experience. I don't think that taking a break from the supplements will cause much of a setback for you. You are doing this for medical reasons so I think it does have some benefits. Just go back to the doses you were taking after the test is over.

It is not clear what test (name of the test) you had that showed 15 as the result.

Well that is progress. I can't register at the site because the box with text in it that you have type to show you can read the screen OK only comes up as a red X in a little square.

Yes, there was some serious stress which is still not completely resolved yet. I was pretty sick after that stress, fatigue, muscle weakness, mood swings, irrational fears, trouble spleeping, etc. But I am working on the problems with the synthetic form of b6 which gave me some digestive issues. I supplement enzymes all the time (meaning with all meals AND also on an empty stomach) and sometimes I supplement some bi-carbonate. (Some meals that are not so heavy don't seem to need the bi-carb so.) I think I have what would be considered pancreatic insuffiency. My pancreas was not producing the bi-carb and enzymes, so I am supplementing those. A severe b6 and zinc deficiency would explain why my pancreas is not producing bi-carb and enzymes. I don't know if the enzymes would help lower the b6 dose. (I started the enzymes only about two months ago, so probably have another 4 months more of supplementing these doses of enzymes.) I think if it did help it would be a small decrease only in the b6. But I do feel that the pryodixine (synthetic) form is easier to tolerate with the enzymes.

Where can I read something about methylation? I have no idea what it is but it is exactly something that is not quite right in Staś. Organix showed both methylation cofactors high (one, related to B12 even very high). Intervention options: B12 and folic acid. (Other abnormalities: high xanthurenate, i.e. impaired tryptophan metabolism; rec. P5P; high glucarate, i.e. hepatic phase I and II detox abnormality, rec. N-acetylcysteine, glutathione and hepatic support; very high D-Arabinitol,i.e. candida, of course - I hate this nasty thing) But honestly, I have no idea on what basis our doctor recommended amino acids and 5-HTP. I will read carefully Claire's link on them and will make sure to ask our doc. So far, I already have cut Tri-Amino (Arginine/Ornithine/Lysine) by half. When supplementing either typtophan or 5htp you need sufficient amounts of pryodoxine or you will experiecne the toxicty of tryptophan, which is xanuthuric acid and some other metabollic waste products (excreted in urine). This is a problem your child tested postive for. (Other abnormalities: high xanthurenate.) This is not what you want. You need more more vitamin b6. Without enough niacin and supplementing either typtophan or 5 htp you can develop a NAD deficiency. NAD is an important brain chemical. The body can contert tryptophan into niacin. http://www.eagle-min.com/faq/faq100.htm I don't know what deficiencies your child was diagnosed as having, but there is a simple test to see how he responds to niacin (the form that causes the flushing). This form raises histamine levels. Low histamine types over-methylate. There are a few books that I know about out on methylation. Craig Cooney's is easy to read. He has a website too. There are some others though. Give your child 50 mg. of niacin and see if that causes the flush. If 50 mg. of niacin produces a flush then that person has high histamine levels. (Folic acid should be avoided and only niacinamide or non-flushing forms of niacin should be used. B12 can also raise histamine levels too, but this is not so clear cut. You have to consult on a case by case basis for b12 in under-methylators.) This person would supplement some other things like calcium and magnesium to help lower histamine levels. If it takes something like 250 mg. of niacin to produce a flush then that person has low histamine levels. Taking high doses of the niacin forum that causes flushing is essential. Folic acid is also important as is b12. You can ask your doctor to test your child's blood for histamine levels too.

Actually, taking just 5htp is not really a good idea. The body needs sufficient amounts of b6 to convert tryptophan (same really as 5htp) into serotonin. So, taking 5htp may cause some toxicity if there is even a slight b6 deficiency. Also it is important to have sufficent amounts of niacin. Tryptophan can be converted into niacin first, then into serontonin. So, you also must have sufficient niacin or you could have a NAD (nicotinamide adenine dinucleotide) deficiency. NAD is an important brain chemical. I have read that taking melatonin also can be a problem with someone on SSRIs. Melatonin and serotonin are similar in structure I believe. I think I read that taking melatonin and SSRIs might cause a stroke. I made this mistake briefly years ago and didn't have a stroke. But not good to mix these things. http://www.emedicine.com/med/topic1977.htm

I forgot to recommend magnesium. When you take high doses of b6 you must take magnesium or you will have the problem at those doses of tingling in the hands and feet. I have read and have experienced this myself and it is when you don't take enough magnesium with those high doses of b6. I don't use any other brand of magnesium except Maginex. I read in Mildred Seelig MD's book on magnesium about this special form. It does not cause any GI problem. It can be embarassing having a bowel movement in a public restroom because of the magnesium causing volcanic like parastolic contractions. Maginex does not cause me any of those problems and all other magnesium supplements seem to do that to me, even Floridex which is made from foods and plants. You can buy what ever type you want, of course, but you need to supplement magnesium with all the b6.

I don't recommend you do this on your own. But I can tell you what I know and what seems to work for me. (And I am an adult.) I take more than 2,000 mg. of b6 each day. I take the bulk of that in pryidoxine form, using the 250 mg. capsule. I either take 500 mg. four times a day or sometimes I will do 750 mg. with breakfast and lunch and 500 with dinner. When I started the supplements I had started at 1,000 mg. per day. I would only take 500 mg. with breakfast and 500 mg. with lunch. I couldn't take b6 any later than that in the beginning because it would prevent me from sleeping. Now I don't have that problem for some reason. Also increase the doses slowly. Try increasing the dose by one quarter. Too much of an increase and your body will let you know by vomiting most likely. You should use some p-5-p. Just take 50 mg. of p-5-p each time you supplement the pyridoxine. That combo of 50 mg. of p-5-p should be enough of the active form. BrainTalk forum has been down and Fran does know her stuff on pyroluria. I wish that forum were back online. I would take 600 mg. of zinc each day when I was in the loading phase. That is 200 mg. of zinc with each meal. After the loading phase I basically just took about half that amount, either 90 mg. or 100 mg. of zinc with each meal. Sometimes that dose is still not quite enough for me and may take a little bit more sometimes. There is a loading phase with zinc but not for b6 for some reason. I use different form of zinc. Sometimes the citrate, sometimes the twinlabs which I think is glucanate. I don't think it makes that much of a difference. Sometimes the one in the right dose is probably the way to go. But sometimes I try a different form to change things up. I also like the sublingual form of p-5-p by source naturals. Sometimes I just like the convenience of this form and it does seem to work pretty quickly. I get this need to chew on the inside of my mouth. It doesn't always last very long but when it happens sometimes I like to take the subL p-5-p and I feel the b6 hitting my brain almost instantly. That form works great for me. Do not forget copper and manganese when taking high doses of zinc. When you do take copper you may not be able to take more than 12 mg. per day (6 mg. per meal). Too much copper will make you nauseated. So, if you forget the copper it can be a slow process to get your copper levels back up. I have read that for pyroluria they recommend you take either evening primrose oil or borage oil. If you are an adult and have pyroluria you might also seriously consider adding some digestive enzymes. I am more than 2 years into supplementing with vitamins and minerals. But a while back the b6 was not working for me and I was having some digestive problems. I now believe that the bulk of b6 being in the snythetic form is why I was having this problem. My body was telling me in a number of ways that my pancreas was not doing its job. And for me it wasn't just enzymes, but I needed to supplement bicarbonate too. I have read the first thing that the pancreas stops producing is bicarb, then enzymes and then the last is insulin. Philpott and Kalida's book Brain Allergy said that with severe b6 and zinc deficiency the pancreas is not able to function properly. (Both those nutrients are critical for protein digestion.) I know those enzymes has helped and particulary with the b6. I still use the p-5-p but now if I forget I won't feel much difference. I don't know if you have any digestive issues at all. Mine weren't much to speak of really. Mostly belching, which was eliminated with the bicarb. I honestly beleive that digestive enzymes are important for adults with pyroluria. (Enzymes for children with pyroluria I am not really sure about though.) I am now using digestive enzymes (with food) and systemic enzymes (taken on an empty stomach) and think this is something you may need to include as well. Unfortunately using enzymes can be a bit complex.

I would like to suggest a product called Zinc Status which sells in health food stores for less than $20. In the UK would be called Zinc (or Zink) Talley. Zinc Status will tell you if you child has a zinc deficiency. This test works. You can tell immediately if your child does NOT have a zinc deficiency because they will likely make a face or complain about the nasty taste. That is how this product works, if you can't taste it then it indicates a deficiency. Zinc plays a role in taste sensation. For the price, this product is excellent to have around to check again if the deficiency is corrected. I have severe nutritional deficiencies which are only treated by orhtomolecular. I know that the dose to treat a deficiency can be surprisingly high to some people. It can take a pretty high dose for several months sometimes to correct a deficiency. One way you can know that the deficiency is corrected and the dose can be lowered is to use Zinc Status for zinc levels. But it is always good to consult with your doctor on this.

I have read that many people can eat a normal diet if they take the right enzymes. Many people but not everyone. I highly recommend the book Enzymes for Autism and other Neurological Disorders by Karen Defelice. I think it is possible to try to have a normal life for your child with food issues if you are willing to try some enzymes. Defelice talks about Houston Neurtoceuticals having enzymes for those with gluten or cesium problems. These may help only, meaning that your child can have some gluten every third or fourth day, or it may mean that as long as your child takes the enzymes anything is OK. With enzymes and food problems it is really a matter of trail and error. Another book that is helpful for this problem is Brain Allergies: The Psychonutrient and Magnetic Connections by Philpott and Kalida. This book explains how to fast and then do the rotation diet. This book is in print and has some useful tips for dealing with these problems. I use orthomolecular to treat my nutritional deficiencies. Anyone with a problem with salicylates usually has a sulfur deficiency or a problem with sulfation. This is, I believe, a treatable condition. It is a sign of a nutritonal imbalance. Of course there are enzymes that can help with this problem too. But usually problems with salicylates means a nutritional imbalance, possibly high histamine levels.

Rice is high in histidine. Histidine is an amino acid that the body converts into histamine. Histamine makes you sneeze, turns your skin red, makes your eyes water, etc. You may have high histamine levels which were made worse by the rice. High histamine would explain your allergies. You can ask you doctor to do a blood test to check your histamine levels. Orthomolecular uses high doses of nutrtional supplements to balance histamine levels in the body. This is not the same idea as taking anti-histamines.

I happen to think that it may be a nutritional problem in some cases, not all. But the nutritional deficiencies can cause other problems too, like pancreatic problems. I have severe nutritional deficiencies which were never diagnosed by any doctor. (I happened to discover them myself, luckily.) But the problem with nutritional deficiencies is that it does lead to other problems, including liver problems but also pancreas problems. The pancreas is so important for digestion because it produces enzymes for digesting fats, carbs and protein, besides some other stuff. There is no name for a condition like sluggish pancreas. And this is like when fatigue was a widespread problem and some people said either your adrenal glands develop Addisons (serious failure) or your adrenals function just fine. But the idea that anyone might have sluggish adrenals was never really recognized by most medical experts. Now, I think a sluggish pancreas may be a real problem but since it is not recognized or has some technical name, it doesn't exist as far as medical research is concerned. This site talks about excema and amaylase. http://www.enzymes.com/protease_deficiency.html I honestly think that doctors never consider nutrition and may not consider digestive or absorption issues either. But these problems can go hand in hand.

Iit sounds like you acted out on your anger toward her and cheated on her. That is the problem with having strong feelings and then acting on those feelings. The people we are closest to we have the strongest feelings for. But these feelings for people close to use can change from love to anger to hurt to something else different. Acting out on these feelings is a bad idea overall because the feelings usually subside or die away at some point but the consequences of the actions may never be taken back. That is why when you have this type of problem with a mate or someone close communication is always the best strategy. If you say something incorrect or even hurtful you can take that back but you can never really take back your actions. I think you have to sort out your feelings so you can have a conversation with her. She is the one you need to talk to about this in order to resolve it. But you really can't do that if you are not sure how you feel at this point. If you are still feeling hurt, or still believing she cheated on you, or maybe you just feel guilty about your actions??? But, whatever you feel now may change tomorrow. It helps if you know what it is you want. Otherwise you can't ask for what you want and expect you will get it. A therapist or a close trusted friend can sometimes help you see things more objectively when you "suspect" problems with your mate. In the future it can be helpful to have someone be your sounding board to give you feedback and perhaps point out the possibility that she is not cheating. You should try to learn from this to avoid doing this in the future. Talk to someone else or to talk to her if you think something is going on. But taking actions based on your suspicions or assumptions will end up getting you in hot water. I don't know what happened and that is not really the point. The point is when you are ready to work things out then you should have a heart to heart with her. If you are not ready to work things out then don't have a sit down yet. IF you are open to being honest about your mistakes and asking for forgiveness for your actions then you are ready to have that talk. But trying to talk to someone who you feel you may accuse of something is not going to be a productive conversation but probably will end up keeping the argument going or just make things worse somehow else. You need to be clear on what you can offer up to her for what you may have done to her and what you would like or hope from her. You need to be clear on what you want or expect from her. You also need to be clear on how willing you are to forgive her too. That is how you can try to move past this incident. Sometimes things like this happen because people grow apart or feel neglected or something; but, open honest communication can actually make a relationship stronger after a betrayal has happened. We all make mistakes in life. Being able to forgive others (and ourselves) is an incrediable tool for being happy.

Some people can have naturally high histamine levels. But, your homocysteine (HCY) levels are not about your histamine levels per se but more an indication if you are methlating properly. High histamine means a tendency to undermethylate. This is someone who needs the right combination of supplements that increase methylation rates in the body. I am not recommending that you try what I explain because this is to help you understand this topic AND this is not something you should do yourself without medical supervision. Orthomolecular treats high histamine types. They under methylate and the body rids itself of histamine through methylation and sulfation. So increasing methylation means these nutritional supplements also help release histamine from the body. The supplements generally known for high histamine types is methionine, a sulfur containing amino acid and calcium and magnesium which also release histamine. There are others too that help, but that is not that important to go into every nutrient. The point is that some nutrients actually raise histamine so these supplements should actually be avoided by a person with high histamine levels (histadelic). Naicin, in the form that causes the flush is one. That naicin flush is actually the basophil and mast cells filling up with histamine. And both folic acid and vitamin b12 raise histamine levels. Folic acid is actually something for high histamine types to avoid completely. The b12 may need a blood test or something but b12 is less important than folic acid. And any other form of naicin beside the flushing type would work find for a high histamine type. That is a basic though not complete explanation of how to supplement for high histamine levels. Anyone can develop high HCY levels because their body is not properly methylating. That can mean they over methlate too much perhaps, or they could be under methylating. Without the proper nutrition, it seems, methylation may not work exactly as it is supposed to. Orthomolecular uses megadose nutrtional suppelements to treat real conditions like high histamine levels or low histamine levels. But biochemists, like Craig Cooney, have published their own stuff on how to use nutritional supplements for improving methlyation rates too. Cooney's book might be great for someone with normal histamine levels because his doses are lower than what ortho uses. But it is possible for people to have normal histamine levels and who want to insure they don't have any problems at all with methylation working in their body. And even though your histamine levels are in the normal range your body may still need some help with better methylation rates. You may still be missing some nutrients that would help your methylation. Methylation does so much more than just release histamine, so histamine is not as extensive a topic as methylation. So just having normal histamine levels can not indicate that methylation is functioning properly for sure.