Elevated IgG's, mean anything?

[ShannonOtown]

Just wanted to get back with everyone on my appointment with the infectious disease doctor. I'm seeing this type of doctor b/c I've had a fever since March and my primary or ENT can't find an infection. My MP IGG are extremely high and increasing... so are my son's IGG scores. But our IGMs are low.

 

So during my appointment I flat out asked if there is a concern if my IGGs are high/increasing, but my IGMs are low. He said yes, especially if other symptoms are presenting themselves (fevers, rashes, coughs, etc). When my son just went to his Infect D doc, that doctor said no concern at all... everyone will show IGG of MP. I also asked him if you already had exposure/infection, then the IGM will not show a high scores and the answer was correct. You will not show a high IGM IF YOU ALREADY HAVE HAD A MP INFECTION.

 

How many of our children have had fever, cough, rashes, upper-respiratory infections. I'm sure all our children at some point during their life has had a MP infection. I know my son had a year where he did nothing but cough, so much we had to buy a nebulizer, but I never tested IGM MP.

 

I guess the point is, don't count on the IGM to show infection. If it's a re-infection, the IGM will not show high results. You have to look for increased titers in the IGG, so you will have to test, then retest a few weeks later.