kim Posted May 5, 2010 Report Posted May 5, 2010 This explains how different antibiotics are thought to be involved in immunomodulation Current Molecular Pharmacology, 2008, 1, 68-79 Immunomodulatory Properties of Antibiotics http://www.bentham.org/cmp/samples/cmp%201-1/Nau.pdf
MomWithOCDSon Posted May 5, 2010 Report Posted May 5, 2010 This explains how different antibiotics are thought to be involved in immunomodulation Current Molecular Pharmacology, 2008, 1, 68-79 Immunomodulatory Properties of Antibiotics http://www.bentham.org/cmp/samples/cmp%201-1/Nau.pdf Thanks for that! I've been searching the web for a convincing link between abx and anti-inflammatory affects thereof, so glad to add this to my arsenal!
trggirl Posted May 6, 2010 Report Posted May 6, 2010 Another thanks! I'm glad to have this as I was just talking to my pediatrician about this issue.
T_Mom Posted May 7, 2010 Report Posted May 7, 2010 Great find! What a team this forum is in information-- Where else can it be said that individuals are so closely tied to sharing the pieces of such an illness puzzle? Great find--thank you.
Mary M Posted May 7, 2010 Report Posted May 7, 2010 Oh, thank you for sharing this. I've been trying to understand the science behind this.
MomWithOCDSon Posted May 8, 2010 Report Posted May 8, 2010 Interestingly enough, if I'm reading this right (and that's a big "if," given my scientific deficits! ), antibiotics in the class of Augmentin (b-lactam) are one class for which little data regarding anti-inflammatory properties is available. In fact, the paper says, "One of the major differences between b-lactam antibiotics and the other groups seems to be the lack of anti-inflammatory properties of b-lactams." And yet, many of our kids have done well on Augmentin. This seems to add further support to the idea that it is the clavulanic acid in Augmentin that provides and immune modulatory/anti-inflammation benefit. OR . . . is it that clavulanic acid has an anti-depressant/anti-anxiety effect? Check this out: Clavulanic acid And this: Enterically coated amox-clav (XR) and anti-inflammation in colitis
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