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Posted
This explains how different antibiotics are thought to be involved in immunomodulation

 

Current Molecular Pharmacology, 2008, 1, 68-79

Immunomodulatory Properties of Antibiotics

 

http://www.bentham.org/cmp/samples/cmp%201-1/Nau.pdf

Thanks for that! I've been searching the web for a convincing link between abx and anti-inflammatory affects thereof, so glad to add this to my arsenal!

Posted

Great find! What a team this forum is in information-- Where else can it be said that individuals are so closely tied to sharing the pieces of such an illness puzzle?

 

Great find--thank you.

Posted

Interestingly enough, if I'm reading this right (and that's a big "if," given my scientific deficits! ;) ), antibiotics in the class of Augmentin (b-lactam) are one class for which little data regarding anti-inflammatory properties is available. In fact, the paper says, "One of the major differences between b-lactam antibiotics and the other groups seems to be the lack of anti-inflammatory properties of b-lactams."

 

And yet, many of our kids have done well on Augmentin. This seems to add further support to the idea that it is the clavulanic acid in Augmentin that provides and immune modulatory/anti-inflammation benefit.

 

OR . . . is it that clavulanic acid has an anti-depressant/anti-anxiety effect? Check this out:

 

Clavulanic acid

 

And this:

 

Enterically coated amox-clav (XR) and anti-inflammation in colitis

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