FYI- recently published papers

[Phasmid]

J Child Neurol. 2010 Mar 5. [Epub ahead of print]

 

A Case of PANDAS Treated With Tetrabenazine and Tonsillectomy.

Fusco FR, Pompa A, Bernardi G, Ottaviani F, Giampà C, Laurenti D, Morello M, Bernardini S, Nuccetelli M, Sabatini U, Paolucci S.

 

Santa Lucia Foundation IRCCS Hospital, Rome, Italy.

 

PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) is a rare clinical syndrome characterized by the presence of tics, Tourette syndrome, obsessive-compulsive disorder, or chorea in the context of an immediately precedent streptococcal infection. In this report, we describe the case of an 11-year-old boy who developed PANDAS with severe choreic movements. The criteria for PANDAS diagnosis were met. Moreover, serum antibrain antibodies were present. The patient was initially treated with tetrabenazine 12.5 mg twice daily with remission of the neurological symptoms. Subsequently, the patient underwent tonsillectomy and has been asymptomatic since, with antistreptolysin O titer levels in range.

[lss]

Article on the drug:

 

 

http://www.usatoday.com/news/health/2008-1...ease-side_N.htm