immune problem and PANDAS

[kg5123]

KG5123

 

My PANDAS kid also has had a thyroid problem as well as PANDAS symptomos of very severe vocal tics.

 

The son is curreny in a stable condition as he has been on monthly IVIG (50 grams per each time) since February this year

at a Connecticut immune doctor clinic. Before the start of IVIG, he failed 12 of the 14 pneumo titers -- less than 1 and close to zero for the 12 titers, meaning he has no ability to produce antibodies that can fight off strep infections. He had also an overall IGG slightly below a normal range and subclass IGG 4 also slightly below a reference range.

 

The parent's strong conviction is this pnumo titer failure is the primary culprit for his PANDAS symptoms. We are convinced that his weak immune defense system as shown in the failed pneumo titers has caused not only PANDAS symptoms but also tyroiditis, a symptom which also emerges in the son twice or three times a year.

 

My conviction is based on a description I found in the explanation of common variable immune deficiency (CVID) listed in the Immuno Deficiency Fondation website. My PANDAS kid is also diagnosed as CVID due to the low IGG problem.

 

Following is the quote from the website.

''Although patients with CVID have a depressed antibody response and low levels of immunoglobulin in their blood, some of the antibodies that are produced by these patients may attack theri own tissues (autoantibodies)..........The autoantibodies may also cause arthritis or endocrine disorders, such as thyroid disease.''

 

As explained in the quote, I suspect that my son's PANDAS symptoms and the thyroid problems are both derivatives of symtoms caused by the body's inability to fight off strep.

 

I would welcom any comments. Thank you.

[ShaesMom]

KG5123

 

My PANDAS kid also has had a thyroid problem as well as PANDAS symptomos of very severe vocal tics.

 

The son is curreny in a stable condition as he has been on monthly IVIG (50 grams per each time) since February this year

at a Connecticut immune doctor clinic. Before the start of IVIG, he failed 12 of the 14 pneumo titers -- less than 1 and close to zero for the 12 titers, meaning he has no ability to produce antibodies that can fight off strep infections. He had also an overall IGG slightly below a normal range and subclass IGG 4 also slightly below a reference range.

 

The parent's strong conviction is this pnumo titer failure is the primary culprit for his PANDAS symptoms. We are convinced that his weak immune defense system as shown in the failed pneumo titers has caused not only PANDAS symptoms but also tyroiditis, a symptom which also emerges in the son twice or three times a year.

 

My conviction is based on a description I found in the explanation of common variable immune deficiency (CVID) listed in the Immuno Deficiency Fondation website. My PANDAS kid is also diagnosed as CVID due to the low IGG problem.

 

Following is the quote from the website.

''Although patients with CVID have a depressed antibody response and low levels of immunoglobulin in their blood, some of the antibodies that are produced by these patients may attack theri own tissues (autoantibodies)..........The autoantibodies may also cause arthritis or endocrine disorders, such as thyroid disease.''

 

As explained in the quote, I suspect that my son's PANDAS symptoms and the thyroid problems are both derivatives of symtoms caused by the body's inability to fight off strep.

 

I would welcom any comments. Thank you.

 

My daughter also has a CVID dx and Pandas. She also has a history of recurrent illness since the age of 2. She has been on monthly IVIG since July. I agree with everything you've said BUT that doesn't mean I believe this stands true for every child with Pandas. I do believe that my dd's immune system problems contributed to her getting Pandas.

[faith]

KG,

have your son's vocal tics resolved since IVIG? what were you doing before that? I am dealing with this in a big way right now too.

 

 

thanks

Faith

[kg5123]

KG,

have your son's vocal tics resolved since IVIG? what were you doing before that? I am dealing with this in a big way right now too.

 

 

thanks

Faith

 

Basically, the problem of severe vocal tics has been resolved since the son has been on IVIG on a monthly basis.

Currently, conditions are very stable with less frequent minor and mild tics.

 

For nearly 20 months before the start of IVIG, the son's nasty vocal tics had been very very distruptive and rampant and he had been

absent from school for most of the period.