Advances in Autism Research

[kim]

I think these are some very important concepts to at least have a little understanding of. It sure appears to me that much of this applies to TS too. As many of you know the sulfur/sulfur transferese are of the utmost interest to me.

 

http://www.autism.com/medical/research/adv...metabolics.html

 

Advances in Autism Research

compiled by Teresa Binstock for ARI

April 2008

 

 

Metabolic pathways -- Clinical Significance Methionine synthase - Glutathione - Homocysteine - etc

 

In recent years, several studies have presented data and an overview of a primary metabolic pathway relevant to many and perhaps most cases of autism (1-4). Jill James and her colleagues have published widely in peer-reviewed journals, as has Richard Deth and members of his team. Their findings in autism are among the most important to be published in recent years. The intra-cellular pathways to which these researchers are calling attention have treatment ramifications already being utilized by clinicians (eg, 5-7).

 

The "methionine cycle" merits our attention (reviewed in 44, free online). Most human genes are controlled by methylation, and errors of methylation can affect how genes function or malfunction. Atypical methylation has been found in autism (1). Many reviews of methylation are available (eg, 8-17). Some focus upon nutrients(eg, 12). Others specifically mention transsulferation and homocysteine (eg, 11) and ramifications for toxicology (eg, 13). All studies in these domains - and not just those presented herein - are relevant to autism in ways delineated by James et al, Deth et al (eg, 1-4) and others.