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Some questions for the group. Can someone explain how a child goes from High CamKII to PANS? DS has Lyme - diagnosed in 2013 - sudden onset of tics in 2012. Cunningham panel came back with CamKII of 147 - very high

So here is my stab at what happened :

Lyme triggered an immune response which went haywire - causing autoimmunity and high levels of antibodies against Basal ganglia which is showing up as high CamKII numbers. Is this theory / hypothesis correct?

Am I missing something? Trying to build a mental model of what is going on...and what treatments help bring down the CamKII numbers....

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