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Posted

Steroids depresses the immune system. When there is an underlying active infection (strep or Lyme), prednisone can cause symptoms to emerge which the immune system is ordinarily able to keep at bay.

Posted

I too would be considering an underlying infection(s).

 

We have the same experience, bad with steroids but good experience with anti-inflammatories in that sometimes the anti-inflammatories will help take the edge off, ever-so-slightly. We are dealing with strep, mycoplasma, lyme, bartonella, babesia. Steroids are contraindicated in the case of lyme.

  • 2 weeks later...
Posted

Hi puppy dog,

The quantity of prednisone and whether ther is a good taper seems to make a difference from my experience. Our ds was on pred this summer and it helped a bit, but ibuprophen seemed to regulate more. I wonder if medrol (predisolone) might be different. I've read it has better activity for neurological inflammation.

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