Anyone use Thorne Methyl-Guard Plus?

[JAG10]

Anyone use this on a regular basis?

[mdmom]

Yes, both my son and daughter take this for MTHFR mutations. They each take 2/day. I cannot tell you if it helps or not, as they take so many supplements and meds.

[LNN]

Not sure the methylB12 in this product would be very effective. Most B12 swallowed doesn't survive the gut. When DD refused to do a sublingual, I dissolved it in a cup of water and she'd drink it. She tested B12 deficient doing it this way. Finally got her to take it sublingually and her complaints of fatigue went away (haven't re-tested the B12 levels yet). But even sublingually, supposedly only 10% actually gets absorbed. So most of the B12 in the Thorne may not become available.

 

That in mind, it's an expensive way to get some methylfolate and P5P. Solgar has metafolin (methylfolate) in 400mcg and 800mcg tablets for a whole lot less http://www.amazon.com/Solgar-Folate-400-Mcg-Metafolin/dp/B001LQY9ZO/ref=sr_1_1?s=hpc&ie=UTF8&qid=1386508925&sr=1-1&keywords=solgar+metafolin+400 and you can get P5P pretty inexpensively http://www.amazon.com/P-5-P-Pyridoxal-5-Phosphate-25-60-Caps/dp/B004EK2QMW/ref=sr_1_7?s=hpc&ie=UTF8&qid=1386509209&sr=1-7&keywords=p-5-p. Then use a sublingual methylB12, which is how my DH gets his "fix".

 

For lower doses of methylfolate, you can use the Methylmate B drops from Holistic Health and then take a sublingual methylB12, which is how we do it for DD.

 

I know a combo product is attractive from a pill load perspective, but B12 that's swallowed is probably a waste. At least that's been my experience and what I've been told and read.