LP results came in mail.....Help

[qannie47]

Ok, I am telling myself that if there really was something to worry about, somebody would have called instead of just mailing this....

 

All other tests for LP normal. Except for Two well defined "O" bands. The report went on to say suggestive of MS.........WHAT? But then went on to say not definitive, and needs to be collaborative with other tests.

 

A note at bottom read, " Contacted patient's PCP (his peds doc?), and noted to him the 2 positive O bands. Because his Protein levels are borderline low and all other CFS tests are not remarkable, we do not find these bands clinically signifigant".

 

When I researched on internet, 2 O bands can be indicative of MS.

 

Anybody know anything about this?

 

Also, it also stated that these O bonds are inhibiting "synthethis of Gammuglobin" which, when I read on that is all apart of the immune system, autoimmune, and effects the central nervous system....

 

So if not MS, could this be indicative of big picture of central nervous system issues caused by autoimmune issues that could be indicative of Pandas? This is an afterthought.

 

UGH....what I really want to know is about these O bands though....

[PowPow]

So, I am not a neurologist (I WISH!!) but, they would not be clinically significant, if your child had no symptoms.

Oligoclonal bands are markers of autoimmunity & your kid has (had?) them in their CSF! Sounds significant to me.

here is something for you to look at & Dr Dale is a PANS guy, if I am correct :

 

http://www.ncbi.nlm.nih.gov/pubmed/20871402

 

PM'ing you, too.

[JoyBop]

I just pm'ed you something about this.

 

"The myelin basic protein level is elevated during acute exacerbations of MS. Oligoclonal bands (OCBs) are found in 83% to 95% of patients in whom definite MS is eventually diagnosed.

 

OCBs are also seen in 25% to 50% of patients with other inflammatory diseases of the nervous system, including viral, bacterial, and fungal infections and CNS vasculitis. "

 

The fact that his protein was borderline low, it could just be showing what you really want to see, inflammatory disease of the nervous system including viral, bacterial or fungal infection. If he protein was high and he had clinical symptoms I would tend to be more nervous.

 

I suppose you are supposed to call your PCP for a referral to a specialist? IT seems odd they didnt include informaation on who/when to follow up. When they right "information passed on to PCP" they are passing the buck to your pediatrician.

 

I wouldnt worry too much about MS for now, but I can understand your worry. Thats what we moms do.