Anti-inflammatories

[bigmighty]

Anyone have experience with either of these anti-inflammatories? Quercetin is found in grapefruit and Luteolin in olive oil or olive seed oil. Thanks.

[rowingmom]

I decided to use luteolin (Lutimax) only, as some children have issues quercetin. We dose once per day, and we also use curcumin.

 

Here is an article on brain inflammation and the use of another supplement containing both luteolin and quercetin from a site with a lot of good information on brain inflammation.

 

http://www.mastcellmaster.com/documents/brain-health/J-Clin-Psychopharm-2011-Brain-Inflammation.pdf

 

Sorry to say, we have never had instant results with any anti-inflammatory, including advil.

[MomWithOCDSon]

We use quercitin daily . . . have been for a couple of years now. We actually use a SolaRay supplement called "QBC" which contains quercitin, bromelaine and Vitamin C. My understanding is that quercitin acts as a natural antihistamine, actually preventing production of histamine at the T-cell level in the body. Decreasing histamine would, one would think, decrease inflammation. I know that its helped both DS and me with our seasonal and household allergies.

[LNN]

We use quercetin as-needed as an anti-histamine. I love it b/c there's no drowsiness, no spaciness, just relief. The down side is that on high pollen days, we end up dosing every 4 hours. We don't use it as an anti-inflammatory as it doesn't seem to influence/calm down behaviors the way motrin does. Here's a good overview by Theorharides at Tufts http://www.bioxtract.com/plant-based-actives/quercetin/index.html

 

I've read good things about luteolin but never tried it. I've heard mixed reviews on Lutimax.

 

One note to look into in the quercetin if you have Mediterranean heritage. Most commercial quercetin comes from Fava beans, which can be a problem is you have a certain genetic mutation. http://en.wikipedia.org/wiki/Glucose-6-phosphate_dehydrogenase_deficiency But my DD, who is 1/2 Greek, seems to be ok with regular quercetin. If it's a concern, there's this product http://www.algonot.com/neuroprotek.php but it's a lower dose and didn't seem to do much for my DD.

[bigmighty]

Thanks, all. This is very helpful.

[bigmighty]

LLM - what brand of quercetin and from whom do you purchase? Thanks.

[smartyjones]

LLM -- do you build up a level with quercitin before allergy season -- or do you just use as needed?

thanks.

[LNN]

My DD and I use this - mostly during allergy season http://www.amazon.com/Now-Foods-Quercetin-Bromelain-Veg-Capsules/dp/B002JNK8EY/ref=sr_1_3?s=hpc&ie=UTF8&qid=1362332048&sr=1-3&keywords=quercetin but I always have some on hand. As MomWithOCDSon says, bromelain and vitamin C help absorption. But I get the kind w/o Vit C b/c we already supplement with it separately at a higher dose. I generally like NOW Foods because they follow GMP (good mfg practices, which is meant to ensure that quality is consistent) and they routinely inspect their suppliers. But not every single supplement I've gotten from then seems to work "the best" - for instance I don't think their Resveratrol is very effective and I use a different brand for that. I also like Source Naturals, tho they tend to be a little higher priced.

[NancyD]

We've been using Querciplex for many years. Love it! Can't be without it!! DD17 takes 1000 mg quercitin bid.

[LNN]

LLM -- do you build up a level with quercitin before allergy season -- or do you just use as needed?

thanks.

 

We just use as needed, no need to build up or taper down. From April-mid-June, we'll each take one capsule in the morning, then usually another after school. Then a zyrtec at bedtime (which is a 24 hr dose). But we do it more based on symptoms rather than a strict dosing. If it's a rainy day and allergy symptoms are less, we'll back down or even skip the day. We use it for symptomatic relief. DD started sublingual allergy drops last month (stopped allergy shots last yr - too traumatic for DD - 18 mos of shots and her needle phobia got worse and worse). It's remotely possible this season won't be as bad for her but most likely, the drops won't make a difference until next yr.

 

MomWith and NancyD are using it as part of a daily anti-inflammatory regimen, so their dose schedules are different.

[NancyD]

Since we've been using it as part of our daily regimen we have no more need for Zyrtec or other anti-histimines and no need for allergy shots. No more seasonal allergy problems and, when combined with Transfer Factor on a daily basis, colds are non-existent or very short-lived! I used to suffer from chronic bronchitis each year for over 20 years and that is now a thing of the past.

 

P.S. if I had to choose 3 supplements I could never be without....it would be Querciplex, Transfer Factor, and D3!

Edited March 4, 2013 by NancyD

[bigmighty]

Thanks, Nancy.