Need help finding an article

[LNN]

Saw this article in the NYT today but it's very vague. Talks about finding 4 "chemicals" that turn autoimmune diseases "on" or "off" and are tied to the immune system. But the article never mentions the names of those 4 chemicals. Wondering if anyone has access to the full article?

 

The summary is here: http://www.nytimes.com/2013/01/21/health/study-pinpoints-what-activates-disease-causing-genes.html?_r=0

 

In their paper, published Sunday in Nature Biotechnology, the researchers reported measurement techniques that enabled them to sort things out. They found hundreds of chemical tags but only four that seemed truly related to the disease. Those four were in a cluster of genes that controls the immune response and that was known to affect the risk of rheumatoid arthritis, said Dr. Andrew Feinberg of Johns Hopkins, a lead author of the study. In particular, the tags were in a gene called C6orf10 whose function is unknown.

 

The chemical tags may help determine if a person with a gene that increases risk of developing a disease actually gets the disease. There were people in the control group who had gene variations associated with arthritis risk, but they did not have those four chemical tags and did not have the disease.

[tpotter]

Saw this article in the NYT today but it's very vague. Talks about finding 4 "chemicals" that turn autoimmune diseases "on" or "off" and are tied to the immune system. But the article never mentions the names of those 4 chemicals. Wondering if anyone has access to the full article?

 

The summary is here: http://www.nytimes.com/2013/01/21/health/study-pinpoints-what-activates-disease-causing-genes.html?_r=0

 

In their paper, published Sunday in Nature Biotechnology, the researchers reported measurement techniques that enabled them to sort things out. They found hundreds of chemical tags but only four that seemed truly related to the disease. Those four were in a cluster of genes that controls the immune response and that was known to affect the risk of rheumatoid arthritis, said Dr. Andrew Feinberg of Johns Hopkins, a lead author of the study. In particular, the tags were in a gene called C6orf10 whose function is unknown.

 

The chemical tags may help determine if a person with a gene that increases risk of developing a disease actually gets the disease. There were people in the control group who had gene variations associated with arthritis risk, but they did not have those four chemical tags and did not have the disease.

 

 

They might not be mentioning specifics to make sure no one steals their research (I would think this is ongoing research.) Just a thought.

[pr40]

this is as far as I could get, beyond this you go to have subscription

http://www.nature.com/nbt/journal/vaop/ncurrent/full/nbt.2487.html