Insurance covered IgG testing (PPO)

[kim]

My sons also have tics and we recently had IGg testing done through MAYO

labs. As I understand it, they send this testing on to IBT labs. I spoke with

someone at MAYO who said this is Flouroenzyme Immunoassay testing. I'm

wondering if anyone can comment on the reliability of this type testing? My

insurance covered this test so I went for it, but my Pediatrician is unable to help

with the results, as he had no idea what it even was.

 

13 year old son tested positive to wheat, barley, rye, oat

9 yr. old egg, peanut, pork and cow's milk.

 

Under reference range, there was only <2. Most of the results were 5 and

6's except 9 yr. old who is an extremely limited eater had a 13 for peanut

(peanut butter is one of about 4 foods he'll eat).

 

I also had the Organix Dysbiosis Profile done on youngest son through

Metametrix. His D-Arabinitol was 51 which put him in about the 75-80% range? I take

it this means that 75% of the children 12 and under had a lower reading?

Again, I'm wondering how many people have used this test and if you felt the

results were reliable as an indication of a yeast problem. Any comments would

be greatly appreciated.

 

Kim

Reply.........(from another parent)

Dear Kim,

 

The amazing fact is that the body is "believing" that the food is

something bad. When there is a bad digestion process, food molecules

are not well broken (hydrolyzed) and due mainly to its size, the body

can not see those molecules as food but as an bad invader (antigen).

 

Once those big and bad food molecules enters to the body through the

intestinal wall, the body defense mechanism is to put a "flag" on them

in order to indicate to defense cells (leukocytes) that those

molecules shall be destroy.

 

The "flag" to signal the invader molecules is the Antibody called IgG

Immunoglobulin G. So if your test is indicating that you have more

than 2, it means that recently the body has detected some invader

molecules and is having a "lot of flags" circulating around ready to

bind another invader big molecule.

 

IgG test basically means that some of the food molecules that gives

high values were detected in the blood and are being processes as

antigens. So for example, in the case of peanut high value, it

indicates that the body is "processing" the peanut by using the immune

system. Sometimes the body mechanism is to use the enzymes of the

immune system to end digestion of big molecules. It seems to be the

indication of this high value. This is bad because those enzymes are

there for eliminating bacteria, yeasts, virus and bad cells, not for

doing digestion.

 

Oral enzymes are going to help you for two basic points:

 

- Improve hydrolysis of food molecules, in the way the body will not

recognize them as antigen.

 

- Reduce the high values of circulating antibodies.

 

Regards,

 

VICTOR

 

 

> Victor,

>

> Thank you so much for the reply. The high reading for peanut gave

this test

> credibility in my mind because it's one of the things conventional

allergy

> testing showed a mild reaction to, and again, because it's one of

the few

> foods he eats. The pork reaction confused me, because he hasn't

eaten any meat

> of any kind since baby food dinners. I can't imagine where he

would even get

> trace exposure to pork.

>

> One of my main concerns was that this test would miss a sensitivity

to

> something like dairy or wheat (he will eat 1 type of cracker and

pretzels), orange

> juice etc. I would hate to feel ok about giving these things if

this test

> was not as reliable as ELISA or other tests it seems like most have

done.

>

> I was wondering if I could have your permission to post your reply

to

> another group? Since this was a test that my insurance covered, and

I was able to

> get reg. Ped to order it, I thought others on a TS/tic board might

be

> interested too. Again, thank you!

>

> Kim

REPLY

 

Kim,

 

Thanks for your answer. Maybe you do not have to analyze the lab

results in such detailed way. Because, what the antibody flags is

sometimes not so easy to catch. Antibody is very small and can just

bind very small parts on a food molecule. For example it can happens

that as your kid is not eaten meat, then the antibody was confusing

the pork meat because it is having the same molecule part that it

binds elsewere.

 

Anyway, by looking the results what is evident is a framework of

general bad nutrition in which the body is sensing several foods as

antigens (fortunatelly not as allergens). It can be more like a

diagnosis of leaky gut.

 

If you start with enzymes, you will eliminate the bad framework, the

leaky gut and the running antibodies. You can place my message in

other places.

 

Regards,

 

VICTOR

[kim]

If anyone is trying to talk their Dr. into ordering IgG testing, this may help convince them.

 

Gluten Ataxia and Post-Streptococcal Central Nervous System

Syndromes: Emerging Immune-mediated Disorders of the Central Nervous

System?

 

Wills A, Dale R, Giovannoni G.

 

Institute of Neurology, Queen Square, London WC1 3BG, United Kingdom.

G.Giovannoni@ion.ucl.ac.uk.

 

There is an "emerging concept" that central nervous system

dysfunction can be caused by an aberrant immune response triggered by

exogenous antigens such as the food allergen gluten or streptococcal

infection. The hypothesis of a gluten sensitive ataxia remains

unproven, but is worthy of consideration. The data in support of this

hypothesis require critical review before any treatment

recommendations can be formulated. The idea that anti-gliadin

antibody seropositivity per se justifies the term "gluten

sensitivity" is important because it offers potential therapeutic

possibilities, including simple exclusion diets, for patients with

anti-gliadin antibody-associated ataxia. Post-streptococcal basal

ganglia dysfunction has various manifestations, all of which fall

into a relatively well-defined symptom complex or syndrome. Anti-

basal ganglia antibodies that are associated with serologic evidence

of recent streptococcal infection are a potential diagnostic marker

for this group of disorders, which includes Sydenham's chorea (SC) as

the prototype. More recently subjects with pediatric autoimmune

neuropsychiatric disorders associated with streptococcal infection,

Tourette's syndrome, obsessive-compulsive disorder and other movement

disorders have been described in association with anti-basal ganglia

antibodies. The apparent overlap between the clinical phenotype of

SC, pediatric autoimmune neuropsychiatric disorders associated with

streptococcal infections, Tourette's syndrome, and obsessive-

compulsive disorder suggests that they may represent one disease

entity. The current working hypothesis is that antibodies induced in

response to streptococcal infection cross-react with antigenic

determinants in the basal ganglia resulting in basal ganglia

dysfunction. Although the experimental evidence is incomplete, there

is sufficient evidence to support immune-mediated basal ganglia

dysfunction as an emerging clinical entity. This has important

implications for the diagnosis and treatment of subjects with these

disorders. The latter includes the judicious use of antibiotic

prophylaxis and immunomodulatory therapies. Apart from the diagnosis

and management of SC, no consensus exists regarding the diagnosis and

management of the other clinical entities within this group of

disorders.

[Giselle]

Awesome Kim - thanks for posting all this!!!!

Giselle

[kim]

No problem Giselle

 

Your posts have been soooooo helpful. I think so many times we soak up every post and get so much from them, but don't take the time to let the poster know how truly helpful their post was. Yours have been such a wealth of information, so thanks right back to you for many, many wonderful posts!!!!

[kim]

bumping for azhorsegal

 

This is another "main stream" medical article discussing this subject

 

http://scholar.google.com/scholar?hl=en&lr...ent+and+...%22+

 

It has been speculated that the relatively high incidence of adverse reactions to food proteins in infancy, especially to cows’ milk protein, could be the result of an increased gut permeability to large molecules and the immaturity of local and systemic immunological responses.

[azhorsegal]

bumping for azhorsegal

 

This is another "main stream" medical article discussing this subject

 

http://scholar.google.com/scholar?hl=en&lr...ent+and+...%22+

 

It has been speculated that the relatively high incidence of adverse reactions to food proteins in infancy, especially to cows’ milk protein, could be the result of an increased gut permeability to large molecules and the immaturity of local and systemic immunological responses.

 

Thanks Kim, My daughter had her blood drawn today for both the IgA tests, and unlike the one post said my pediatrician new exactly what tests were needed for Celiac, even though he thought my Naturopathic doctor's unconventional ways of testing for allergies was a hoax. He still understood the seriousness of making sure my daughter does not have Celiac. We are also scheduled to see an allergist next week to get blood tests to confirm her food allergies. Should here about the Celiac test sometime next week. Thanks for bumping this post up, gave me some more understanding on how this all works. THANKS!

 

I'm so grateful to everyone here, as this tic disorder that my daugther has been diagnosed with doesn't seem as scary as it did, though I still know things might, and probably will get worse before they get better. At least I don't feel alone and if something happens it's nice to have people to talk with that's already been down this road. Thanks to everyone!

[Guest]

azhorsegal,

 

I bumped up a list of tests that can uncover issues which commonly impact tics that I thought you may be interested in. Often certain labs specialize in certain lab tests.

 

Carolyn

[azhorsegal]

azhorsegal,

 

I bumped up a list of tests that can uncover issues which commonly impact tics that I thought you may be interested in. Often certain labs specialize in certain lab tests.

 

Carolyn

 

THANKS!!!