Hladr4

[Tamistwins]

Can anyone explain to me what hladr4 is and it's relation with Lyme?

Thank you!

[LNN]

Can anyone explain to me what hladr4 is and it's relation with Lyme?

Thank you!

 

Roughly 25% of the population has a genetic predisposition to having problems with handling the toxic load that comes with lyme. This is why the lyme vaccine was only on the market for 2 yrs in 2000-2001. So many people had adverse reactions and actually developed arthritis and other complications from the vaccine because they had the genetic marker of HLA-DR4. Other people have other variants of this gene that makes it difficult for them to handle mold toxins. So they can be in a building with a little mold and struggle when others seem to have no problem.

 

This explains it best:

http://www.survivingmold.com/diagnosis/the-biotoxin-pathway

then go to

lab results

 

this has the same info but I like the way it's presented:

http://www.publichealthalert.org/Articles/scottforsgren/biotoxin%20pathway.html

[Tamistwins]

Can anyone explain to me what hladr4 is and it's relation with Lyme?

Thank you!

 

Roughly 25% of the population has a genetic predisposition to having problems with handling the toxic load that comes with lyme. This is why the lyme vaccine was only on the market for 2 yrs in 2000-2001. So many people had adverse reactions and actually developed arthritis and other complications from the vaccine because they had the genetic marker of HLA-DR4. Other people have other variants of this gene that makes it difficult for them to handle mold toxins. So they can be in a building with a little mold and struggle when others seem to have no problem.

 

This explains it best:

http://www.survivingmold.com/diagnosis/the-biotoxin-pathway

then go to

lab results

 

this has the same info but I like the way it's presented:

http://www.publichealthalert.org/Articles/scottforsgren/biotoxin%20pathway.html

Thank you so much for those informative links. I got this explanation from Dr. Jones office yet I haven't received any specific info to our case.

 

HLA patterning is done on any child diagnosed with tick-borne illness because HLA DR2 and HLA DR4 are associated with an increased tendency to have a Lyme induced autoimmune reaction especially if bands 31 and 34 are present. The results of the HLA patterning can help a lyme dr determine treatment protocol.

 

HLA DR2 and HLA DR4 are each of the thousands of markers(antigens) found on the surface of our cells to denote "self" in immune system recognition. These markers are found in 15% of the population and have no pathological significance unless one has Lyme or other tic borne illness. HLA DR2 and HLA DR4 together with the Lyme Borrelia burgdorferi spirochete 31 or 34 antibodies are associated with the development of an auto-immune process which persists until the Lyme bacterium Borrelia burgdorferi is eradicated. This Lyme induced auto-immune process is rendered less intense by Plaquenil (hydroxychloroquine), an antimalarial antibiotic which also kills spirochetes.

 

In addition, the presence of HLA DR2 and HLA DR4 predisposes a person with LYME disease to have an auto-immune reaction, which explains the possibility of having a high C3d immune complex. A high immune complex indicates one to be making antibodies to their own tissues. A high immune complex indicates one to be making antibodies to their own tissues. A high immune complex result can decrease while Lyme is resolving or has resolved.