New Article

[Mary M]

I don't know if this article has been posted on the forum or not...

 

http://jcn.sagepub.com/content/early/2010/11/17/0883073810378534

 

I can't get the whole article to appear. The above is just the free abstract. If you want to read the entire article email me back at mmcrombez@sbcglobal.net and I will forward the article to you.

Mary

from Michigan

[T_Mom]

I can't help but think that this is a very important article for the cause. Thanks for posting it--

Edited November 29, 2010 by T.Mom

[LNN]

This is a quote from the end of the article (bolding is mine):

 

"To clarify the phenomenology, classification, mechanisms,

and optimal therapy of these conditions, we recommend that

the following be carried out for any child or adolescent presenting

with acute onset of a choreoathetotic, tic, or myoclonic

movement disorder, particularly when combined with

psychiatric features and following a febrile illness: standard

throat culture; blood testing for antistreptolysin O and anti-

DNAse B antibodies; echocardiography; MRI of the brain and

lumbar puncture for examination of glucose; total protein; and

cells and myelin basic protein. Antistreptolysin O and anti-

DNAse B titers should be rechecked after about 6 weeks.

Patients with a movement disorder should be examined by a

movement disorders specialist or at least videotaped for later

review. Patients with chorea and evidence of a recent GABHS

infection (within the prior 6 months) should be treated with

antibiotics for suspected Sydenham chorea as recommended

by the American Heart Association.22,28"

 

 

 

Thanks Mary!

[kimballot]

This is a quote from the end of the article (bolding is mine):

 

"To clarify the phenomenology, classification, mechanisms,

and optimal therapy of these conditions, we recommend that

the following be carried out for any child or adolescent presenting

with acute onset of a choreoathetotic, tic, or myoclonic

movement disorder, particularly when combined with

psychiatric features and following a febrile illness: standard

throat culture; blood testing for antistreptolysin O and anti-

DNAse B antibodies; echocardiography; MRI of the brain and

lumbar puncture for examination of glucose; total protein; and

cells and myelin basic protein. Antistreptolysin O and anti-

DNAse B titers should be rechecked after about 6 weeks.

Patients with a movement disorder should be examined by a

movement disorders specialist or at least videotaped for later

review. Patients with chorea and evidence of a recent GABHS

infection (within the prior 6 months) should be treated with

antibiotics for suspected Sydenham chorea as recommended

by the American Heart Association.22,28"

 

 

 

Thanks Mary!

 

That was in an article by KURLAN??!?? WOW ... something is certainly happening to turn the tide. We go from "I'm sorry.. there is no need to check any further. If you child had strep throat just before tics it does not mean anything. Everyone has strep throat from time to time." to..."do a lumbar puncture and follow up ASO and DNASE B"!! Wow! I wonder what Kurlan is in the works to be printed next month!!

[EAMom]

It is amazing that not 1 of the 4 cases had a GABHS culture done...even the one that was "more classic" PANDAS (the 8 year old and symptoms showing up less than 1 week after infection).

 

(I don't know how to cut and paste the chart without it becoming distorted.)