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I am confused about the 23andme results for my DS's vs. Their OATS or ONE test results. They were both homozygous for COMT suggesting supplementation with hydroxy B12 but their nutrievaluations indicated their levels for B12 are fine. So does that mean I should not supplement or does it mean they need more than the average person? Also, they were both homozygous for the GAD1 gene, indicating high glutamate and low GABA and to supplement with Taurine, The anime, NAC, Glycine, VitaminB3. But when tested, my youngest DS was very high in Taurine already. So I am not sure if that means I should avoid taurine with him or if his body is dumping it and needs more. Also, should a supplement with all suggested supplements or just try each til I find one that works. So confused. I am in SC and no doc's here that really understand the genetic testing.
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FASCINATING case study about a 16 yr. old boy presenting with neuropsych symptoms (severe, with hallucinations) All resolved with H. Pylori treatment and B12 injections. For those of you (like us) with the MTHFR C6677T snp, he had it also, and the psychiatrist noted that that mutation may have been why his symptoms presented differently than normal B12 deficiency signs. Also of note - if we have malabsorption issues, it's important to "bypass the pesky gut". (injections or sublingual...) At least until we can find out what types of gut problems we have, and FIX them! http://evolutionarypsychiatry.blogspot.com/2012/11/b12-deficiency-and-psychosis-case-study.html