Thanks for you prompt reply. I know one of my uncles do have chronic tics and he has still got it. But both I and my husband don't have tics. Neither my parents and my husband's parents. I guess extended family are counted as well. He has no allergy, no vaccine and hardly take any antibiotics ( except twice when he got toothache). He did have a few red lump and hives on its body for a few days before the tics flared up. He couldn't sleep well before he felt so itchy. That is the only thing a bit unusual, otherwise I can't see anything different. I have tried the epsom salt for his bath and still waiting for the natural calm supplement. I am living in uk, so I have to get the supplement shipped to me from USA which will take a few days. I do wish it can help. I also tried Tic Tamer, but it doesn't seem to work. So I stopped using it. Do you know how long this severe head shaking will last?