Report Rheumatic disorders developed after hepatitis B vaccination in PANS / PANDAS (Lyme included) Posted March 25, 2015 This is interesting to me because I got a hep b shot as a requirement for college... That same year at the age of 18 I develped severe joint issues with my fingers on both hands. This was pre the internet and we honestly never made the connection that it could be the hep b shot. instead we were trying to come up with things like stress related, lyme, weather related (it was cold where I went to school but it was cold where I lived before so it didn't make much sense.. and it happens now at any season but more in the winter) My parents took me to a rheumatologist who at the time just said arthritic like conditions.. I can go many years and not have any problems and then all of a sudden out of the blue it starts.. I have seen different rheumatologists.. tested negative for everything they tested for (lyme, lupus and a million other things)... My ds who has pandas did receive the heb b vaccine as a baby..