another titer questions

[KaraM]

HI,

 

My dd7 was diagnosed with OCD in December. At that thime her throat culture was negative.

In March, her ASO was 200-400. Her Anti DNAse B was 450. Both of these are slightly above normal. She did have confirmed strep two years ago.

I understand it is best ot have her titers done again so we can see if there is a change in one direction or another, but when is the best time to do this?

 

We just started Zithromax Tuesday after getting back very high Cunningham test scores. She is on a five day treatement dose and then will be on prophylactic at least until we see another doc in June. (Our pediatrician is not well versed, but I feel thankful he is listening to me, the test results and this board (thanks Buster for the Q&A - I brought it to him and he thought it was very reasonable and well written).

 

Does it make more sense to test her if/when her symptoms are better and expect to see a decrease in the titer levels. Or should I retest if/when her symptoms are exacerbated? Does it matter?

 

Thanks,

Kara

[Joan Pandas Mom]

My son's ASO was 1014 in October. He was tested in Dec. after 7 weeks of 2000 Mg Augmentin XR. They were still up at some # above 800. The lab didn't test higher than 800. He was tested in Feb. they were at 776 and again in March down to 648. Dr. T told me they can take a year to come down. I have been told different things by different people but it seems to me when they are dropping, I see improvements.

 

HI,

 

My dd7 was diagnosed with OCD in December. At that thime her throat culture was negative.

In March, her ASO was 200-400. Her Anti DNAse B was 450. Both of these are slightly above normal. She did have confirmed strep two years ago.

I understand it is best ot have her titers done again so we can see if there is a change in one direction or another, but when is the best time to do this?

 

We just started Zithromax Tuesday after getting back very high Cunningham test scores. She is on a five day treatement dose and then will be on prophylactic at least until we see another doc in June. (Our pediatrician is not well versed, but I feel thankful he is listening to me, the test results and this board (thanks Buster for the Q&A - I brought it to him and he thought it was very reasonable and well written).

 

Does it make more sense to test her if/when her symptoms are better and expect to see a decrease in the titer levels. Or should I retest if/when her symptoms are exacerbated? Does it matter?

 

Thanks,

Kara

[sf_mom]

Anti-DNase-b can be very slow to rise and fall. ASO is indicative of a past strep infection. You could drive yourself a little nuts by retesting because the 'rise and fall rate' also varies from person to person.

 

If you are getting proper treatment and have a good Dr. on board I think its better to look at your daughter symptomatically. Save yourself the worry and your daughter from the additional bloodwork! If you haven't already probably more important to test Subclasses, Mycoplasma pneumonia, Lymes, etc. to discover what the possible source or if there are co-infections to help determine best antibiotic treatment.

 

-Wendy

 

 

HI,

 

My dd7 was diagnosed with OCD in December. At that thime her throat culture was negative.

In March, her ASO was 200-400. Her Anti DNAse B was 450. Both of these are slightly above normal. She did have confirmed strep two years ago.

I understand it is best ot have her titers done again so we can see if there is a change in one direction or another, but when is the best time to do this?

 

We just started Zithromax Tuesday after getting back very high Cunningham test scores. She is on a five day treatement dose and then will be on prophylactic at least until we see another doc in June. (Our pediatrician is not well versed, but I feel thankful he is listening to me, the test results and this board (thanks Buster for the Q&A - I brought it to him and he thought it was very reasonable and well written).

 

Does it make more sense to test her if/when her symptoms are better and expect to see a decrease in the titer levels. Or should I retest if/when her symptoms are exacerbated? Does it matter?

 

Thanks,

Kara

Edited March 31, 2010 by SF Mom

[justinekno]

Is there any significance to the anti-DNase-b rising after being on penicillen for almost two months?Our ASO went down (by a couple of points) but anti-DNase-b rose from 1:170 - 1:240. Not much but I'm curious.

 

Justine

 

Anti-DNase-b can be very slow to rise and fall. ASO is indicative of a past strep infection. You could drive yourself a little nuts by retesting because the 'rise and fall rate' also varies from person to person.

 

If you are getting proper treatment and have a good Dr. on board I think its better to look at your daughter symptomatically. Save yourself the worry and your daughter from the additional bloodwork! If you haven't already probably more important to test Subclasses, Mycoplasma pneumonia, Lymes, etc. to discover what the possible source or if there are co-infections to help determine best antibiotic treatment.

 

-Wendy

Edited March 31, 2010 by justinekno

[LNN]

Kara,

Unless your pediatrician is insisting on it, I wouldn't test titers until you've seen the new doctor. If they fall, the pediatrician might want to pull the prophylactics. Best to let sleeping dogs lie and focus on symptoms. I also second Wendy's post about pursuing other blood work instead (tho this may be part of the blood work that gets ordered with the new doc - might be worth a call to the office to see if the blood draws can be ordered before your first visit so you have some results to discuss as part of the initial visit).

 

Laura