out of sync, pandas, just right ocd -- thoughts?

[marilina]

MomWithOCDSon

you say "deficit of glutamate"......

I read a lot about glutamate as excitotoxin, and about the balance gaba / glutamate, very important for health. also found that children with autism have rather too much glutamate receptors .....

is there something to read about PANDAS-glutamate relation?

thanks

No, actually, the glutamate issue is with respect to OCD, plus I mispoke; it's not a "deficit" of glutamate, but rather a failure to modulate the amount of it overall in the brain. There was a study done at, I believe, Wayne State, in which a series of MRIs performed on OCD kids versus non-OCD kids revealed that OCD kids had higher levels of glutamate active in their brains, and the thought was that these higher levels attributed to an OCD person's greater challenge in "switching off" thoughts rather than perseverating on them and/or circling back to them over and over again. I saw the study referenced and the chief researcher interviewed on a "Dateline" episode about kids with OCD.

 

Then, more recently, one of the other parents here introduced me to the fact that there is a trial currently going on involving a drug called riluzole that might help the modulation.

 

Here are a couple of links I found on the topic:

 

Glutamate-OCD Study

 

"http://www.neuropharmacology.com/rilutek.htm

ok

then corresponds to what I have read. I therefore believe that even children without autism do well in this sense to control the levels of glutamate. avoid aspartate, momo sodium glutamate, reducing or eliminating foods such as tomatoes and peas

[MomWithOCDSon]

ok

then corresponds to what I have read. I therefore believe that even children without autism do well in this sense to control the levels of glutamate. avoid aspartate, momo sodium glutamate, reducing or eliminating foods such as tomatoes and peas

 

Avoiding aspartame and MSG, I get, but why tomatoes and peas? Really? You'd think the "good" in fresh items like that would outweigh the "bad." Anything else on that "to be avoided" list? Do you have a link you could share?