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Very nice indeed, thank you. I am particularly gratified to see discussion of bystander activitation, among other mechanisms, since my personal belief is that the molecular mimicry hypothesis has taken up too much of the stage in PANDAS and there is insufficient appreciation of the importance of bystander activitation. Hopefully other physicians treating PANDAS are reading this article too.

 

For nerds only ...

 

Here is a very recent review article which covers the connection between infection and autoimmunity. This is highly relevant to PANDAS and related disorders.

 

http://www.jleukbio.org/cgi/rapidpdf/jlb.0709517v1

 

Leave the page alone for a few moments and the PDF should appear ....

 

 

Dr. T

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