Behavioral reaction to Benedryl

[mama2alex]

We gave my son Benedryl the other night and he slept like a baby. BUT, the next morning he was extremely agressive and angry. It wasn't exactly a rage, but more like he needed to hit anyone who came near him and was yelling a lot. It wore off in a couple of hours, and was clearly due to the Benedryl.

 

So we were told that he'd be given Benedryl before IVIG to help prevent an allergic reaction. I want them to give him something, because he is very sensitive to lots of things, but not sure it should be Benedryl.

 

Has anyone else seen a similar reaction and is there something you've used in place of Benedryl?

 

Thanks!

[peglem]

I've seen that reaction, but not the next morning. About 1/2 hour after dosing, my daughter has a huge, long rage. Then she falls asleep. Good question about alternatives for that with IVIG.

[mama2alex]

I've seen that reaction, but not the next morning. About 1/2 hour after dosing, my daughter has a huge, long rage. Then she falls asleep. Good question about alternatives for that with IVIG.

 

Thanks so much for your response! Anyone else? I can always ask the doctor or nurse, but I value your collective experiences at least as much.

[BriCanady]

I've seen that reaction, but not the next morning. About 1/2 hour after dosing, my daughter has a huge, long rage. Then she falls asleep. Good question about alternatives for that with IVIG.

 

Thanks so much for your response! Anyone else? I can always ask the doctor or nurse, but I value your collective experiences at least as much.

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My son had an IVIG in November and was given benedryl prior to the IVIG. I had forgotten that as a toddler, he had "rage" episodes with benedryl, and we hadn't given it to him in many years. He had a "burning reaction" the first night and the following nights they "watered down " the benedryl. This helped but it still burned.....just something to think about...

[dabel]

My son just had IVIG last week with Dr.K. Both days he got real surly or edgy at about the same amount of time into the procedure. I think it was because of the Benedryl. I don't know what else you would use but thought I would mention this.

[tantrums]

My son has always gotten very edgy and physically spastic with benadryl - only right after dosing though. If I gave it to him at night, night terrors and thrashing around in his sleep were awful! One time he slammed his head so hard on the headboard that he had a bruise.

 

Claritin made him terribly physically aggressive. Quite scary actually. I think they are different ingredients though?

[Debbie1]

Benadryl always makes my PANDAS son hyper - he is bouncing off the walls, impulsive and whatever PANDAS symptoms he has at the time seem to intensify shortly after taking a dose.