To ShaesMom

[mama2alex]

ShaesMom,

 

In response to your information below (from a previous post) - I spoke to our psychiatrist about this today and I think she finally helped me to understand what you were getting at. (I obviously do not have a scientific mind!) So we looked back at his pneumococcal titers test done in Jan '08 and he was low or extremely low on 5 out of 7 they tested - and he is fully vaxed! Also, they just retested them a month and a half ago (but never told me - I only knew because I got the records to send to Dr. K last week - I thought the blood test was just for allergies). At that point they tested 6 of the original 7 serotypes they had tested in 2008, plus 6 more. They didn't give ref ranges with the recent results, but the new numbers look very low - at least half are .3 or below (plus #26 jumped to 50.7 mcg/ml, which seems very high).

 

Thank you so much for pointing this out to me. It took me a while to catch on, but I am going to call the immunologist in Omaha right away. It's hard to believe his pulmonologist would have seen evidence of an immune deficiency and not told us, but I think it's worth a second opinion.

 

Thanks again!

 

 

 

 

 

My daughter had normal Ig's and Igg subclass results. She failed the Pneumococcal titers vaccine test-she only made antibodies to two of the 14 serotypes. Because she was vaccinated with Prevnar four times between the ages of 2-3 her Immunologist felt she did not need to be revaccinated at this time and started her on monthly IVIG. Our Immunologist is a Clinical Professor at the UCLA School of Medicine and will be there September 23-29 for the Siegel lectures and LA Allergy Society meetings. It also looks like he will be doing some teaching. Get a hold of him somehow and see if he can help find an Immunologist who will test your son's titers without redoing the vaccine and treat. Our Immunologist does not have great bedside manner but he is suppose to be one of the best in the country and is a big wig in with Immune Deficiency Foundation. Roger H. Kobayashi, MD

 

http://allergynebraska.com/index.php?title...3d5d6b601ff9d7a

 

 

Here is a link to the subclass info from the Immune Deficiency Foundation's website. http://www.primaryimmune.org/publications/...pats/e_ch10.pdf

[ShaesMom]

If you look on the lab results there should be a long paragraph explaining the results. It starts out "Note: Serotypes designations.....specific antibody levels of approximately 2.0 mcg/ml were protective against invasive pneumococcal disease."

 

My Immuno doc uses the above 2.0 as his range. Anything below 2.0 is a failure. Diana P's Immuno doc feels anything below a 1.0 is considered a failure. My daughter only scored above 2 of the serotypes. Her immuno also did not feel it was necessary to revax her because she had all the necessary Prevnar vaccines during her regular vaccine schedule.

 

Number 26 (6B) is actually a part of the Prevnar vaccine so I would think a high score would be good.

 

My dd scored <0.3 on seven of the serotypes.

 

your Pulmonogist probably had no clue what it meant.

 

ShaesMom,

 

In response to your information below (from a previous post) - I spoke to our psychiatrist about this today and I think she finally helped me to understand what you were getting at. (I obviously do not have a scientific mind!) So we looked back at his pneumococcal titers test done in Jan '08 and he was low or extremely low on 5 out of 7 they tested - and he is fully vaxed! Also, they just retested them a month and a half ago (but never told me - I only knew because I got the records to send to Dr. K last week - I thought the blood test was just for allergies). At that point they tested 6 of the original 7 serotypes they had tested in 2008, plus 6 more. They didn't give ref ranges with the recent results, but the new numbers look very low - at least half are .3 or below (plus #26 jumped to 50.7 mcg/ml, which seems very high).

 

Thank you so much for pointing this out to me. It took me a while to catch on, but I am going to call the immunologist in Omaha right away. It's hard to believe his pulmonologist would have seen evidence of an immune deficiency and not told us, but I think it's worth a second opinion.

 

Thanks again!

 

 

 

 

 

My daughter had normal Ig's and Igg subclass results. She failed the Pneumococcal titers vaccine test-she only made antibodies to two of the 14 serotypes. Because she was vaccinated with Prevnar four times between the ages of 2-3 her Immunologist felt she did not need to be revaccinated at this time and started her on monthly IVIG. Our Immunologist is a Clinical Professor at the UCLA School of Medicine and will be there September 23-29 for the Siegel lectures and LA Allergy Society meetings. It also looks like he will be doing some teaching. Get a hold of him somehow and see if he can help find an Immunologist who will test your son's titers without redoing the vaccine and treat. Our Immunologist does not have great bedside manner but he is suppose to be one of the best in the country and is a big wig in with Immune Deficiency Foundation. Roger H. Kobayashi, MD

 

http://allergynebraska.com/index.php?title...3d5d6b601ff9d7a

 

 

Here is a link to the subclass info from the Immune Deficiency Foundation's website. http://www.primaryimmune.org/publications/...pats/e_ch10.pdf