article: Bicillin

[jan251]

I don't recall seeing this article posted here though perhaps I missed it:

 

FRI0516 The Largest Cohort of Children and Adolescents with Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus Infection (Pandas): Preliminary Descriptive Analysis

F. Falcini1, A. Meini2, G. Lepri1, D. Rigante3, A. Ferrari2, E. Casalini1, M. Matucci-Cerinic1

Conclusions Our preliminary data in the largest pediatric population with PANDAS ever studied until now show male predominance and familiar recurrence rate over 40%. Clinical onset occurs at a mean age of 8.5±2.9 years with motor tics in 45% of cases. Increased anti-DNase B titer is found in over 30% of patients. Benzathine benzylpenicillin has resulted effective in 3/4 of cases with complete or partial remission of symptoms.

 

It seems to me that's quite a high success rate for Bicillin, no?

[Hrosenkrantz]

our infusion nurse recently mentione this to me. i haven't heard much about bacillin though in the years (!) we have been dealing with thill iillness. Why isn't this treatment discussed/used more?

[Mom23boys]

My boys had 3 months of Bicillin shots. It did nothing. They are IM shots and are extremely painful!!! It is just IM penicillin. Wonder how long these kids were on it and how frequently? We were on the rheumatic fever protocol of once a month.